Recombinant adenovirus-transduced human dendritic cells engineered to secrete interleukin-10 (IL-10) suppress Th1-type responses while selectively activating IL-10-producing CD4 + T cells

Human Immunology

Volumn 65, Issue 11, 2004, Pages 1344-1355

  Rea, Delphine ^a   Laface, Drake ^b   Hutchins, Beth ^b   Kwappenberg, Kitty ^a   Melief, Cornelis J M ^a   Hoeben, Rob C ^a   Offringa, Rienk ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

adenovirus; CD4 + T helper cell; dendritic cell; interleukin 10; tolerance

Indexed keywords

BETA GALACTOSIDASE; CD4 ANTIGEN; INTERLEUKIN 10;

ADENOVIRUS; ARTICLE; CELL CULTURE; CELL MATURATION; CELL PROLIFERATION; CELL SECRETION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; DNA MODIFICATION; GENETIC CODE; GENETIC ENGINEERING; HISTOCOMPATIBILITY COMPLEX; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TISSUE ENGINEERING; UPREGULATION; VIRUS INFECTION; VIRUS RECOMBINANT;

ADENOVIRIDAE; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOKINES; DENDRITIC CELLS; GENETIC VECTORS; HUMANS; INTERLEUKIN-10; LYMPHOCYTE ACTIVATION; TH1 CELLS; TRANSFECTION;

EID: 8844280117     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2004.08.185     Document Type: Article

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