Social motivation is reduced in vasopressin 1b receptor null mice despite normal performance in an olfactory discrimination task

Hormones and Behavior

Volumn 46, Issue 5, 2004, Pages 638-645

  Wersinger, Scott R ^a   R Kelliher, Kevin ^b   Zufall, Frank ^b   Lolait, Stephen J ^c   O'Carroll, Anne Marie ^c   Young III, W Scott ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Aggression; Behavior; Chemosensory; Vasopressin V3 receptor

Indexed keywords

VASOPRESSIN V3 RECEPTOR;

AGGRESSIVENESS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANOSMIA; ARTICLE; ASSOCIATION; CHEMOSENSITIVITY; CONTROLLED STUDY; INSTRUMENTAL CONDITIONING; LATENT PERIOD; MALE; MATING SYSTEM; MOTIVATION; MOUSE; MOUSE STRAIN; NONHUMAN; OLFACTORY DISCRIMINATION; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; SEX DIFFERENCE; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SPECIES COMPARISON; TASK PERFORMANCE;

AGGRESSION; ANIMALS; CONDITIONING, OPERANT; DISCRIMINATION LEARNING; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTIVATION; RANDOM ALLOCATION; RECEPTORS, VASOPRESSIN; SEX FACTORS; SEXUAL BEHAVIOR, ANIMAL; SMELL; SOCIAL BEHAVIOR;

EID: 8844278997     PISSN: 0018506X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yhbeh.2004.07.004     Document Type: Article

References (46)

1. H.E. Albers, and M. Bamshad Role of vasopressin and oxytocin in the control of social behavior in Syrian hamsters (Mesocricetus auratus) Prog. Brain Res. 119 1998 395 408
2. H.E. Albers, J. Pollock, W.H. Simmons, and C.F. Ferris A V1-like receptor mediates vasopressin-induced flank marking behavior in hamster hypothalamus J. Neurosci. 6 1986 2085 2089
3. G. Baird, H. Cass, and V. Slonims Diagnosis of autism Br. Med. J. 327 2003 488 493
4. M. Bamshad, and H.E. Albers Neural circuitry controlling vasopressin-stimulated scent marking in Syrian hamsters (Mesocricetus auratus) J. Comp. Neurol. 369 1996 252 263
5. A.H. Bass, and M.S. Grober Social and neural modulation of sexual plasticity in teleost fish Brain Behav. Evol. 57 2001 293 300
6. N.J. Bean Olfactory and vomeronasal mediation of ultrasonic vocalizations in male mice Physiol. Behav. 28 1982 31 37
7. J.K. Bester-Meredith, and C.A. Marler Vasopressin and aggression in cross-fostered California mice (Peromyscus californicus) and white-footed mice (Peromyscus leucopus) Horm. Behav. 40 2001 51 64
8. I.F. Bielsky, S.B. Hu, K.L. Szegda, H. Westphal, and L.J. Young Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice Neuropsychopharmacology 29 2004 483 494
9. N. Bodyak, and B. Slotnick Performance of mice in an automated olfactometer: odor detection, discrimination and odor memory Chem. Senses 24 1999 637 645
10. A.K. Champlin Strain differences in estrous cycle and mating frequencies after centrally produced anosmia in mice Biol. Reprod. 16 1977 513 516
11. E.F. Coccaro, R.J. Kavoussi, R.L. Hauger, T.B. Cooper, and C.F. Ferris Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects Arch. Gen. Psychiatry 55 1998 708 714
12. J.C. Compaan, R.M. Buijs, C.W. Pool, A.J. De Ruiter, and J.M. Koolhaas Differential lateral septal vasopressin innervation in aggressive and nonaggressive male mice Brain Res. Bull. 30 1993 1 6
13. R. Dantzer Vasopressin, gonadal steroids and social recognition Prog. Brain Res. 119 1998 409 414
14. R. Dantzer, R.M. Bluthe, G.F. Koob, and M. Le Moal Modulation of social memory in male rats by neurohypophyseal peptides Psychopharmacology (Berlin) 91 1987 363 368
15. Y. Delville, K.M. Mansour, and C.F. Ferris Testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus Physiol. Behav. 60 1996 25 29
16. V.H. Denenberg, E. Gaulin-Kremer, R. Gandelman, and M.X. Zarrow The development of standard stimulus animals for mouse (Mus musculus) aggression testing by means of olfactory bulbectomy Anim. Behav. 21 1973 590 598
17. C.F. Ferris, H.E. Albers, S.M. Wesolowski, B.D. Goldman, and S.E. Luman Vasopressin injected into the hypothalamus triggers a stereotypic behavior in golden hamsters Science 224 1984 521 523
18. C.F. Ferris, R.H. Melloni Jr., G. Koppel, K.W. Perry, R.W. Fuller, and Y. Delville Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters J. Neurosci. 17 1997 4331 4340
19. J.L. Goodson, and A.H. Bass Social behavior functions and related anatomical characteristics of vasotocin/vasopressin systems in vertebrates Brain Res. Brain Res. Rev. 35 2001 246 265
20. G. Griebel, J. Simiand, J. Stemmelin, C.S. Gal, and R. Steinberg The vasopressin V1b receptor as a therapeutic target in stress-related disorders Curr. Drug Target CNS Neurol. Disord. 2 2003 191 200
21. E.A. Hammock, and L.J. Young Variation in the vasopressin V1a receptor promoter and expression: implications for inter- and intraspecific variation in social behaviour Eur. J. Neurosci. 16 2002 399 402
22. A. Holmes, M. Heilig, N.M. Rupniak, T. Steckler, and G. Griebel Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders Trends Pharmacol. Sci. 24 2003 580 588
23. T.R. Insel, J.T. Winslow, Z. Wang, and L.J. Young Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation Adv. Exp. Med. Biol. 449 1998 215 224
24. K.R. Kelliher, J. Ziesmann, S.D. Munger, R.R. Reed, and F. Zufall Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice Proc. Natl. Acad. Sci. U. S. A. 100 2003 4299 4304
25. J.P. Kelly, A.S. Wrynn, and B.E. Leonard The olfactory bulbectomized rat as a model of depression: an update Pharmacol. Ther. 74 1997 299 316
26. M.M. Konstantareas, and Y.J. Lunsky Sociosexual knowledge, experience, attitudes, and interests of individuals with autistic disorder and developmental delay J. Autism Dev. Disord. 27 1997 397 413
27. R. Landgraf, E. Frank, J.M. Aldag, I.D. Neumann, C.A. Sharer, X. Ren, E.F. Terwilliger, M. Niwa, A. Wigger, and L.J. Young Viral vector-mediated gene transfer of the vole V1a vasopressin receptor in the rat septum: improved social discrimination and active social behaviour Eur. J. Neurosci. 18 2003 403 411
28. B.G. Leypold, C.R. Yu, T. Leinders-Zufall, M.M. Kim, F. Zufall, and R. Axel Altered sexual and social behaviors in trp2 mutant mice Proc. Natl. Acad. Sci. U. S. A. 99 2002 6376 6381
29. F.L. Moore, and L.J. Miller Arginine vasotocin induces sexual behavior of newts by acting on cells in the brain Peptides 4 1983 97 102
30. C.A. Mossman, and L.C. Drickamer Odor preferences of female house mice (Mus domesticus) in seminatural enclosures J. Comp. Psychol. 110 1996 131 138
31. L.J. Pitkow, C.A. Sharer, X. Ren, T.R. Insel, E.F. Terwilliger, and L.J. Young Facilitation of affiliation and pair-bond formation by vasopressin receptor gene transfer into the ventral forebrain of a monogamous vole J. Neurosci. 21 2001 7392 7396
32. G.M. Realmuto, and L.A. Ruble Sexual behaviors in autism: problems of definition and management J. Autism Dev. Disord. 29 1999 121 127
33. F.A. Rowe, and D.A. Edwards Olfactory bulb removal: influences on the aggressive behaviors of male mice Physiol. Behav. 7 1971 889 892
34. F.A. Rowe, and W.E. Smith Simultaneous and successive olfactory bulb removal: influences on the mating behavior of male mice Physiol. Behav. 10 1973 443 449
35. L.A. Ruble, and N.J. Dalrymple Social/sexual awareness of persons with autism: a parental perspective Arch. Sex. Behav. 22 1993 229 240
36. K. Semsar, F.L. Kandel, and J. Godwin Manipulations of the AVT system shift social status and related courtship and aggressive behavior in the bluehead wrasse Horm. Behav. 40 2001 21 31
37. C. Serradeil-Le Gal, S. Derick, G. Brossard, M. Manning, J. Simiand, R. Gaillard, G. Griebel, and G. Guillon Functional and pharmacological characterization of the first specific agonist and antagonist for the V1b receptor in mammals Stress 6 2003 199 206
38. L. Stowers, T.E. Holy, M. Meister, C. Dulac, and G. Koentges Loss of sex discrimination and male-male aggression in mice deficient for TRP2 Science 295 2002 1493 1500
39. M.L. Terranova, G. Loggi, F. Chiarotti, and G. Laviola Attractivity and social preferences in mice (Mus musculus domesticus): the role of prepubertal sexual segregation and of precocious weaning J. Comp. Psychol. 114 2000 325 334
40. L. Tidmarsh, and F.R. Volkmar Diagnosis and epidemiology of autism spectrum disorders Can. J. Psychiatry 48 2003 517 525
41. R. Tuchman Autism Neurol Clin. 21 2003 915 932 (viii)
42. M.E. Van Bourgondien, N.C. Reichle, and A. Palmer Sexual behavior in adults with autism J. Autism Dev. Disord. 27 1997 113 125
43. S.R. Wersinger, and E.F. Rissman Oestrogen receptor alpha is essential for female-directed chemo-investigatory behaviour but is not required for the pheromone-induced luteinizing hormone surge in male mice J. Neuroendocrinol. 12 2000 103 110
44. S.R. Wersinger, E.I. Ginns, A.M. O'Carroll, S.J. Lolait, and W.S. Young 3rd Vasopressin V1b receptor knockout reduces aggressive behavior in male mice Mol. Psychiatry 7 2002 975 984
45. S.R. Wersinger, M. Christiansen, S.B. Hu, P.W. Gold, and W.S. Young 3rd Aggression is reduced in vasopressin 1b receptor null mice but is elevated in vasopressin 1a receptor null mice Annu. Meet. Soc. Neurosci. 2003
46. L.J. Young, R. Nilsen, K.G. Waymire, G.R. MacGregor, and T.R. Insel Increased affiliative response to vasopressin in mice expressing the V1a receptor from a monogamous vole Nature 400 1999 766 768