The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression

Carcinogenesis

Volumn 25, Issue 11, 2004, Pages 2217-2224

  Caporali, Andrea ^a   Davalli, Pierpaola ^b   Astancolle, Serenella ^b   D'Arca, Domenico ^b   Brausi, Maurizio ^c   Bettuzzi, Saverio ^a   Corti, Arnaldo ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c Nuovo Ospedale S Agostino   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CASPASE; CASPASE 9; CATECHIN; CELL CYCLE PROTEIN; CLUSTERIN; CYSTEINE PROTEINASE; CYTOKERATIN; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; GALLOCATECHIN; GREEN TEA EXTRACT; GROWTH ARREST SPECIFIC PROTEIN 1; HISTONE H3; MESSENGER RNA; PROCASPASE 3; PROCASPASE 8; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VIRUS LARGE T ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; MALE; MALIGNANT TRANSFORMATION; MITOSIS INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROTEIN FUNCTION; TISSUE DISTRIBUTION; TREATMENT FAILURE; TUMOR SUPPRESSOR GENE; UPREGULATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTICARCINOGENIC AGENTS; CATECHIN; CLUSTERIN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; MALE; MICE; MICE, INBRED C57BL; PROSTATIC NEOPLASMS; TEA;

EID: 8844264520     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh235     Document Type: Article

References (30)

1. Huggins,C., Sthephens,R.C. and Hodge,C.V. (1941) Studies on prostatic cancer: 2. The effects of castration on advanced carcinoma of the prostate gland. Arch. Surg., 43, 209.
2. Giovannucci,E. (1995) Epidemiological characteristics of CaP. Cancer, 75, 1766-1777.
3. Liao,S., Kao,Y.H. and Hiipakka,R.A. (2001) Green tea: biochemical and biological basis for health benefits. Vitam. Horm., 62, 1-94.
4. Kao,Y.H., Hiipakka,R.A. and Liao,S. (2000) Modulation of endocrine systems and food intake by green tea epigallocatechin gallate. Endocrinology, 141, 980-987.
5. Liao,S. and Hiipakka,R.A. (1995) Selective inhibition of steroid 5 alpha-reductase isozymes by tea epicatechin-3-gallate and epigallocatechin-3-gallate. Biochem. Biophys. Res. Commun., 214 833-838.
6. Greenberg,N.M., DeMayo,F., Finegold,M.J., Medina,D., Tilley,W.D., Aspinall,J.O., Cunha,G.R., Donjacour,A.A., Matusik,R.J. and Rosen,J.M. (1995) Prostate cancer in a transgenic mouse. Proc. Natl Acad. Sci. USA, 92, 3439-3443.
7. Kaplan-Lefko,P.J., Chen,T.M., Ittmann,M.M., Barrios,R.J., Ayala,G.E., Huss,W.J., Maddison,L.A., Foster,B.A. and Greenberg,N.M. (2003) Pathobiology of autochthonous CaP in a pre-clinical transgenic mouse model. Prostate, 55, 219-237.
8. Gupta,S., Hastak,K., Ahmad,N., Lewin,J.S. and Mukhtar,H. (2001) Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc. Natl Acad. Sci. USA, 98 10350-10355.
9. Bettuzzi,S., Hiipakka,R.A., Gilna,P. and Liao,S. (1989) Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis. Biochem. J., 257, 293-296.
10. Lakins,J., Bennett,S., Chen,J., Arnold,J., Morrissey,C., Wong,P., O'Sullivan,J. and Tenniswood,M. (1998) Clusterin biogenesis is altered during apoptosis in the regressing rat ventral prostate. J. Biol. Chem., 273, 27887-27895.
11. Miyake,H., Nelson,C., Rennie,P. and Gleave,M. (2000) Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in CaP xenograft models. Cancer Res., 60, 2547-2554.
12. Leskov,K.S., Klokov,D.Y., Li,J., Kinsella,T.J. and Boothman,D.A. (2003) Synthesis and functional analysis of the nuclear clusterin: a cell death protein. J. Biol. Chem., 278, 11590-11600.
13. Bettuzzi,S., Davalli,P., Astancolle,S., Caran,C., Madeo,B., Tampieri,A. and Corti,A. (2000) Tumor progression is accompanied by significant changes in the levels of expression of polyamine metabolism regulatory genes and clusterin (sulfated glycoprotein 2) in human CaP specimens. Cancer Res., 60, 28-34.
14. Scaltriti,M., Brausi,M., Amorosi,A., Caporali,A., D'Arca D'Astancolle,S., Corti,A. and Bettuzzi,S. (2004) Clusterin (SGP-2, ApoJ) expression is downregulated in low- and high-grade human prostate cancer. Int. J. Cancer, 108, 23-30.
15. Bettuzzi,S., Scorcioni,F., Astancolle,S., Davalli,P., Scaltriti,M. and Corti,A. (2002) Clusterin (SGP-2) transient overexpression decreases proliferation rate of SV40-immortalised human prostate epithelial cells by slowing down cell cycle progression. Oncogene, 21, 4328-4334.
16. Grassilli,E., Bettuzzi,S., Monti,D., Ingletti,M.C., Franceschi,C. and Corti,A. (1991) Studies on the relationship between cell proliferation and cell death: opposite patterns of SGP-2 and ornithine decarboxylase mRNA accumulation in PHA-stimulated human lymphocytes. Biochem. Biophys. Res. Commun., 180, 59-63.
17. July,L.V., Akbari,M., Zellweger,T., Jones,E.C., Goldenberg,S.L. and Gleave,M.E. (2002) Clusterin expression is significantly enhanced in CaP cells following androgen withdrawal therapy. Prostate, 50, 179-188.
18. Pucci,S., Bonanno,E., Pichiorri,F., Angeloni,C. and Spagnoli,L.G. (2004) Modulation of different Clusterin isoforms in human colon tumorigenesis. Oncogene, 23, 2298-2304.
19. Cussenot,O., Berthon,P., Berger,R., Mowszowicz,I., Faille,A., Hojman,F., Teillac,P., Le Duc,A. and Calvo,F. (1991) Immortalization of human adult normal prostatic epithelial cells by liposomes containing large T-SV40 gene. J. Urol., 146, 881-886.
20. Hollman,P.H.C., Venema,D.P., Khokhar,S. and Arts,I.C.W. (1999) Determination of tea catechins by reverse phase high performance liquid chromatography. Methods Enzymol., 299, 202-206.
21. Gupta,S., Hastak,K., Afaq,F., Ahmad,N. and Mukhtar,H. (2004) Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis. Oncogene, 23, 2507-2522.
22. Gingrich,J.R., Barrios,R.J., Foster,B.A. and Greenberg,N.M. (1999) Pathologic progression of aucthonous prostate cancer in TRAMP model. Prostate Cancer Prostatic Dis., 2, 70-75.
23. Ahmad,N., Feyes,D.K., Nieminen,A.L., Agarwal,R. and Mukhtar,H. (1997) Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J. Natl Cancer Inst., 89, 1881-1886.
24. Egevad,L., Rayford,W., Bergerheim,U., Ekman,P., DeMarzo,A.M., Tibshirani,R., Botstein,D., Brown,P.O., Brooks,J.D. and Pollack,J.R. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc. Natl Acad. Sci. USA, 101, 811-816.
25. Gupta,S., Hussain,T. and Mukhtar,H. (2003) Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells. Arch. Biochem. Biophys. 410, 177-185.
26. Winter,R.N., Kramer,A., Borkowski,A. and Kyprianou,N. (2001) Loss of caspase-1 and caspase-3 protein expression in human prostate cancer. Cancer Res., 61, 1227-1232.
27. 2+ depletion caused nuclear translocation of a 45 kda death-isoform of clusterin and anoikis induction in prostate cells. Cell Death Diff., in press.
28. 2/M-phase arrest and cell death in PC-3 prostate cancer cells. Cancer Res., in press.
29. Hastak,K., Gupta,S., Ahmad,N., Agarwal,M.K., Agarwal,M.L. and Mukhtar,H. (2003) Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. Oncogene 22, 4851-4859.
30. Santilli,G., Aronow,B.J. and Sala,A. (2003) Essential requirement of Apolipoprotein J (clusterin) signalling for IKB expression and regulation of NF-kB activity. J. Biol. Chem., 278, 38214-38219.