IgA antibodies to human tissue transglutaminase: Audit of routine practice confirms high diagnostic accuracy

Scandinavian Journal of Gastroenterology

Volumn 39, Issue 11, 2004, Pages 1078-1082

  Hill, Peter G ^a   Forsyth, J M ^a   Semeraro, D ^a   Holmes, G K T ^a  

^a DERBYSHIRE ROYAL INFIRMARY   (United Kingdom)

Author keywords

Coeliac disease; Endomysial antibodies; Sensitivity and specificity; Tissue transglutaminase antibodies

Indexed keywords

ENDOMYSIUM ANTIBODY; IMMUNOGLOBULIN A ANTIBODY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELIAC DISEASE; CLINICAL PRACTICE; DIAGNOSTIC ACCURACY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MEDICAL AUDIT; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AUTOANTIBODIES; BIOLOGICAL MARKERS; BIOPSY; CELIAC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GTP-BINDING PROTEINS; HUMANS; IMMUNOGLOBULIN A; JEJUNUM; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; TRANSGLUTAMINASES;

EID: 8844263795     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520410008051     Document Type: Article

References (12)

1. Blackwell PJ, Hill PG, Holmes GKT. Autoantibodies to human tissue transglutaminase: Superior predictors of coeliac disease. Scand J Gastroenterol 2002;37:1282-5.
2. Bürgin-Wolff A, Dahlbom I, Hadziselimovic F, Petersson CJ. Antibodies against human tissue transglutaminase and endomysium in diagnosing and monitoring coeliac disease. Scand J Gastroenterol 2002;37:685-91.
3. Mäki M, Mustalahti K, Kokkonen J, Kulmala P, Haapalahti M, Karttunen T, et al. Prevalence of celiac disease among children in Finland. N Engl J Med 2003;348:2517-24.
4. Martini S, Mengozzi G, Aimo G, Giorda L, Pagni R, Guidetti CS. Comparative evaluation of serologic tests for celiac disease diagnosis and follow up. Clin Chem 2002;48:960-3.
5. Bossuyt P, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, et al. Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Br Med J 2003;326:41-4.
6. Oberhuber G, Granditsch G, Vogelsang H. The histopathology of coeliac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol 1999;11:1185-94.
7. Dahele AVM, Aldhous MC, Humphreys K, Ghosh S. Serum IgA tissue transglutaminase antibodies in coeliac disease and other gastrointestinal diseases. Q J Med 2001;94:195-205.
8. West J, Lloyd CA, Hill PG, Holmes GKT. IgA-tissue transglutaminase: validation of a commercial assay for diagnosing coeliac disease. Clin Lab 2002;48:243-6.
9. Feighery C, Abuzakouk M, Jackson J, Clooney A, Dunne J, Willoughby R, et al. Coeliac disease serology: EMA negative disease. In: Cerf-Bensussan N, Brousse N, Caillat-Zucman S, Cellier C, Schmitz J, editors. Proc Xth Int Symp Coeliac Dis. France: John Libbey; 2003. p. 183-90.
10. Bizzaro N, Pasini P, Finco B. False-positive reactions for IgA anti phospholipid and anti B2 glycoprotein I antibodies in patients with IgA monoclonal gammopathy. Clin Chem 1999;45:2007-10.
11. Hill PG, Lloyd A, Holmes GKT. IgA class antibodies to tissue transglutaminase and the detection of selective IgA deficiency [poster abstract 110]. In: Martin SM, editor. Proc Pathol 2000 London: Association of Clinical Biochemists; 2000. p. 138.
12. McMillan SA. Simple method for detecting IgA deficient patients with coeliac disease: preliminary results [poster abstract 20]. In: Proc 11th Int Symp Coeliac Dis, Belfast 2004.