Characterization of functional effects of Z-338, a novel gastroprokinetic agent, on the muscarinic M 1, M 2, and M 3 receptors expressed in Xenopus oocytes

European Journal of Pharmacology

Volumn 505, Issue 1-3, 2004, Pages 31-35

  Doi, Y ^a   Murasaki, O ^a   Kaibara, M ^a   Uezono, Y ^a   Hayashi, H ^a   Yano, K ^a   Taniyama, K ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Gastrokinetic agent; Muscarinic receptor; Z 338

Indexed keywords

ACETYLCHOLINE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; N [2 (DIISOPROPYLAMINO)ETHYL] 2 (2 HYDROXY 4,5 DIMETHOXYBENZAMIDO) 4 THIAZOLECARBOXAMIDE; N [2 (DIISOPROPYLAMINO)ETHYL] 2 [(2 HYDROXY 4,5 DIMETHOXYBENZOYL)AMINO] 1,3 THIAZOLE 4 CARBOXAMIDE; OTENZEPAD; PIRENZEPINE; POTASSIUM CHANNEL; PROKINETIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; IC 50; NONHUMAN; OOCYTE; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ACETYLCHOLINE; ANIMALS; BENZAMIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTROINTESTINAL AGENTS; GENE EXPRESSION; HUMANS; MEMBRANE POTENTIALS; MUSCARINIC ANTAGONISTS; OOCYTES; PIPERIDINES; PIRENZEPINE; POTASSIUM; RATS; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M2; RECEPTOR, MUSCARINIC M3; RECEPTORS, MUSCARINIC; REPRODUCIBILITY OF RESULTS; THIAZOLES; XENOPUS;

EID: 8844258040     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.10.003     Document Type: Article

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