Computational evidence for the enamine mechanism of intramolecular aldol reactions catalyzed by proline

Angewandte Chemie - International Edition

Volumn 43, Issue 43, 2004, Pages 5766-5768

  Clemente, Fernando R ^a   Houk, K N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aldol reaction; Asymmetric catalysis; Density functional calculations; Proline; Reaction mechanisms

Indexed keywords

AMINES; CARBOXYLIC ACIDS; CATALYSIS; COMPUTATIONAL METHODS; CONCENTRATION (PROCESS); PROTONS; REACTION KINETICS;

CYCLIZATION; DENSITY FUNCTIONAL METHODS; INTRAMOLECULAR ALDOL REACTIONS; PROLINE; PROTON TRANSFER;

AMINO ACIDS;

ENAMINE; PROLINE; ALCOHOL DERIVATIVE; ALDEHYDE; AMINE; KETONE; SOLVENT;

ALDOL REACTION; ARTICLE; CALCULATION; CATALYSIS; CATALYST; CHEMICAL BOND; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; DENSITY FUNCTIONAL THEORY; ENANTIOSELECTIVITY; ENERGY; GEOMETRY; MOLECULAR MODEL; PROTON TRANSPORT; REACTION ANALYSIS; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS; BIOLOGY; CHEMICAL MODEL; CHEMISTRY; STEREOISOMERISM;

ALCOHOLS; ALDEHYDES; AMINES; CATALYSIS; COMPUTATIONAL BIOLOGY; CYCLIZATION; KETONES; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PROLINE; SOLVENTS; STEREOISOMERISM;

EID: 8844256133     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200460916     Document Type: Article

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