Management of unresectable stage III non-small cell lung cancer: The role of combined chemoradiation

Seminars in Radiation Oncology

Volumn 14, Issue 4, 2004, Pages 326-334

  Penland, Shannon K ^a,b   Socinski, Mark A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b C AND EN   (United States)

Author keywords

concurrent chemotherapy; consolidation chemotherapy; mediastinoscopy; PET

Indexed keywords

AMIFOSTINE; ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; DOCETAXEL; ETOPOSIDE; GEFITINIB; GEMCITABINE; IRINOTECAN; NAVELBINE; PACLITAXEL; PLATINUM; VINBLASTINE; VINBLASTINE SULFATE;

CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER RESEARCH; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CELL PROTECTION; CLINICAL TRIAL; CLUSTER ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CORRELATION ANALYSIS; CRYOPROTECTION; DATA ANALYSIS; DIAGNOSTIC ACCURACY; DISEASE COURSE; ESOPHAGITIS; GAMMA RADIATION; HEMATOLOGIC DISEASE; HUMAN; LONG TERM CARE; LUNG NON SMALL CELL CANCER; NEUTROPENIA; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; REVIEW; SENSITIVITY ANALYSIS; SIDE EFFECT; STATISTICAL SIGNIFICANCE; THROMBOCYTOPENIA; TOXICITY; TREATMENT PLANNING;

EID: 8844234335     PISSN: 10534296     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semradonc.2004.07.002     Document Type: Article

References (47)

1. American Cancer Society Cancer Facts and Figures 2003 2003 American Cancer Society Atlanta, GA
2. C.F. Mountain Revisions in the international system for staging lung cancer Chest 111 1997 1710 1717
3. F. Andre, D. Grunenwald, J.P. Pignon Survival of patients with resected N2 non-small cell lung cancer evidence for a subclassification and implications J Clin Oncol 18 2000 2981 2989
4. T.C. McLoud, P.M. Bourgouin, P.W. Greenberg Bronchogenic carcinoma analysis of staging in the mediastinum with CT by correlative lymph node mapping and sampling Radiology 182 1992 319 323
5. T. Arita, T. Kuramitsu, M. Kawamura Bronchogenic carcinoma incidence of metastases to normal sized lymph nodes Thorax 50 1995 1267 1269
6. T. Arita, T. Matsumoto, T. Kuramitsu Is it possible to differentiate malignant mediastinal nodes from benign nodes by size? Reevaluation by CT, transesophageal echocardiography and nodal specimen Chest 110 1996 1004 1008
7. E.M. Toloza, L. Harpole, D.C. McCrory Noninvasive staging of non-small cell lung cancer a review of the current evidence Chest 123 suppl 2003 1378S-1346S
8. R.M. Pieterman, J.W. van Putten, J.J. Meuzelarr Preoperative staging of non-small cell lung cancer with positron-emission tomography N Engl J Med 343 2000 254 261
9. M.P. MacManus, R.J. Hicks, D.L. Ball F-18 fluorodeoxyglucose positron emission tomography staging in radical radiotherapy candidates with Non-small cell lung carcinoma powerful correlation with survival and high impact on treatment Cancer 92 2001 886 895
10. M.P. MacManus, R.J. Hicks, J.P. Matthews Positron emission tomography is superior to computed tomography scanning for response-assessment after radical radiotherapy or chemoradiotherapy in patients with non-small cell lung cancer J Clin Oncol 2 2003 1285 1292
11. R.O. Dillman, S.L. Seagren, K.J. Propert A randomized trial of induction chemotherapy plus high-dose radiation vs radiation alone in stage III non-small cell lung cancer N Engl J Med 323 1990 940 945
12. R.O. Dillman, J. Herndon, S.L. Seagren Improved survival in stage III non-small cell lung cancer seven-year follow-up of Cancer and Leukemia Group B (CALGB) 8433 trial J Natl Cancer Inst 88 1996 1210 1215
13. D.H. Johnson, L.H. Einhorn, A. Bartoluccci Thoracic radiotherapy does not prolong survival in patients with locally advanced, unresectable non-small cell lung cancer Ann Intern Med 113 1990 33 38
14. R.F. Morton, J.R. Jett, W.L. McGinnis Thoracic radiation therapy alone compared with combined chemoradiotherapy for locally unresectable non-small cell lung cancer a randomized, phase III trial Ann Intern Med 115 1991 681 686
15. M.G. Trovo, E. Minatel, A. Veronesi Combined radiotherapy and chemotherapy versus radiotherapy alone in locally advanced epidermoid bronchogenic carcinoma a randomized study Cancer 65 1990 400 404
16. J.E. White, T. Chen, R. Reed Limited squamous cell carcinoma of the lung a Southwest Oncology Group randomized study of radiation with or without doxorubicin chemotherapy and with or without levamisole immunotherapy Cancer Treat Rep 66 1982 1113 1120
17. W. Sause, P. Kolesar, S. Taylor Five-year results phase III trial of regionally advanced unresectable non-small cell lung cancer, RTOG 8808, ECOG 4588 SWOG 8992 (abstract 453a) Proc Am Soc Clin Onc 17 1998
18. W.T. Sause, C. Scott, S. Taylor Radiation Therapy Oncology Group (RTOG) 88-08 and Eastern Cooperative Oncology Group (ECOG) 4588 preliminary results of a phase III trial in regionally advanced, unresectable non-small cell lung cancer J Natl Cancer Inst 87 1995 198 205
19. T. Le Chevalier, R. Arriagada, M. Tarayre Significant effect of adjuvant chemotherapy on survival in locally advanced non-small cell lung carcinoma J Natl Cancer Inst 84 1992 58
20. T. Le Chevalier, R. Arriagada, E. Quoix Radiotherapy alone versus combined chemotherapy and radiotherapy in nonresectable non-small cell lung cancer first analysis of a randomized trial in 353 patients J Natl Cancer Inst 83 1991 417 423
21. K. Mattson, L.R. Holsti, P. Holsti Inoperable non-small cell lung cancer radiation with or without chemotherapy Eur J Cancer Clin Oncol 24 1988 477 482
22. T.P. Miller, J.J. Crowley, J. Mira A randomized trial of chemotherapy and radiotherapy for stage III non-small cell lung cancer Cancer Ther 1 1998 229 236
23. C. Blanke, C.B. Ansari, R. Mantravadi Phase III trial of thoracic irradiation with or without cisplatin for locally advanced unresectable non-small cell lung cancer a Hoosier Oncology Group Protocol J Clin Oncol 13 1995 1425 1429
24. C. Schaake-Koning, W. van den Bogaert, O. Dalesio Effects of concomitant cisplatin and radiotherapy on inoperable non-small cell lung cancer N Engl J Med 326 1992 524 530
25. M.G. Trovo, E. Minatel, G. Franchin Radiotherapy versus radiotherapy enhanced by cisplatin in stage III non-small cell lung cancer Int J Radiat Oncol Biol Phys 24 1992 11 15
26. B. Jeremic, Y. Shibamoto, L. Acimovic Hyperfractionated radiation therapy with or without concurrent low-dose daily carboplatin/etoposide for stage III non-small cell lung cancer a randomized study J Clin Oncol 14 1996 1065 1070
27. B. Jeremic, Y. Shibamoto, L. Acimovic Randomized trial of hyperfractionated radiation therapy with or without concurrent chemotherapy for stage III non-small cell lung cancer J Clin Oncol 13 1995 452 458
28. T.A. Hensing, J.S. Halle, M.A. Socinski Chemoradiotherapy for stage IIIA, B non-small cell lung cancer F.C. Detterbeck M.P. Rivera M.A. Socinski Diagnosis and Treatment of Lung Cancer; An Evidence-Based Guide for the Practicing Clinician 2001 W.B. Saunders Company Philadelphia, PA 291 303
29. NSCLC CG Chemotherapy in non-small cell lung cancer a meta-analysis using updated data on individual patients from 52 randomized clinical trials BMJ 311 1995 899 909
30. K. Furuse, M. Fukuoka, M. Kawahara Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine and cisplatin in unresectable stage III non-small cell lung cancer J Clin Oncol 17 1999 2692 2699
31. W.J. Curran, C.B. Scott, C.J. Langer Phase III comparison of sequential vs. concurrent chemoradiation for patients with unresected stage III non-small cell lung cancer (NSCLC) initial report of Radiation Therapy Oncology Group (RTOG) 9410 (abstr 1891) Proc Am Soc Clin Oncol 2000 19
32. W.J. Curran, C.B. Scott, C.J. Langer Long-term benefit is observed in a phase III comparison of sequential vs. concurrent chemo-radiation for patients with unresected stage III nslc RTOG 9410 (abstr 2499) Proc Am Soc Clin Oncol 2003 22
33. H. Choy, W.J. Curran, C.B. Scott Preliminary report of locally advanced multimodality protocol (LAMP): ACR 427: a randomized phase II study of three chemo-radiation regimens with paclitaxel, carboplatin, and thoracic radiation (TRT) for patients with locally advanced non-small cell lung cancer (LA-NSCLC) (abstr 1160) Proc Am Soc Clin Oncol 2002 21
34. F. Pierre, P. Maurice, R. Gilles A randomized phase III trial of sequential chemo-radiotherapy versus concurrent chemo-radiotherapy in locally advanced non-small cell lung cancer (NSCLC) (GLOT-GFPC NPC 95-01 study) (abstr 1246) Proc Am Soc Clin Oncol 2001
35. P. Zatloukal, L. Petruzelka, M. Zemanova Concurrent versus sequential radiochemotherapy with vinorelbine plus cisplatin (V-P) in locally advanced non-small cell lung cancer. A randomized phase II study (abstr 1976) Proc Am Soc Clin Onc 2000
36. E.E. Vokes, J.E. Herndon II, J. Crawford Randomized phase II study of cisplatin with gemcitabine or paclitaxel or vinorelbine as induction chemotherapy followed by concomitant chemoradiotherapy for stage IIIB non-small cell lung cancer cancer and Leukemia Group B Study 9431 J Clin Oncol 20 2002 4191 4198
37. K.S. Albain, J.J. Crowley, At Turrisi Concurrent cisplatin, etoposide plus radiotherapy for pathologic stage IIIB non-small cell lung cancer a Southwest Oncology Group phase II study (S9019) J Clin Oncol 20 2002 3454 3460
38. D.R. Gandara, K. Chansky, K.S. Albain Consolidation Docetaxel after concurrent chemoradiotherapy in stage IIIB non-small cell lung cancer Phase II Southwest Oncology Group Study S9504 J Clin Oncol 21 2003 2004 2010
39. C.A. Perez, K. Stanley, G. Grundy Impact of radiation technique and tumor extent on tumor control and survival of patients with unresectable non-oat cell carcinoma of the lung report by the RTOG Cancer 50 1982 1091 1099
40. R. Arriagada, T. Le Chevalier, E. Quoix GETCB (Groupe d'Etude et Traitemet des Cancers Bronchiques) FCLCC (Federation Nationale des Centres de Lutte contre le Cancer) and the CEBI trialists ASTRO (American Society for Therapeutic Radiology and Oncology) plenary: effect of chemotherapy on locally advanced non-small cell lung carcinoma: a randomized study of 353 patients Int J Radiat Oncol Biol Phys 20 1991 1183 1190
41. M. Saunders, S. Dische, A. Barrett Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer a randomized multicentre trial Lancet 350 1997 161 165
42. C.P. Belani, W. Wang, D.H. Johnson Induction chemotherapy followed by standard thoracic radiotherapy (Std. TRT) vs. hyperfractionated accelerated radiotherapy (HART) for patients with unresectable stage IIIA & B non-small cell lung cancer (NSCLC) phase III study of the Eastern Cooperative Oncology Group (ECOG 2597) Proc Am Soc Clin Oncol 22 2003 622 (abstr 2500)
43. J.A. Hayman, M.K. Martel, R.K. Ten Haken Dose escalation in NSCLC using three-dimensional conformal radiation therapy update of a phase I trial J Clin Oncol 8 1990 1543 1555
44. M.A. Socinski, J.G. Rosenman, J. Halle Dose-escalating conformal thoracic radiation therapy with induction and concurrent carboplatin/paclitaxel in unresectable stage IIIA/B non-small cell lung carcinoma a modified phase I/II trial Cancer 92 2001 1213 1223
45. J.G. Rosenman, J.S. Halle, M.A. Socinski High-dose conformal radiotherapy for treatment of stage IIIA/IIIB non-small cell lung cancer technical issues and results of a phase I/II trial Int J Radiat Oncol Biol Phys 54 2002 348 356
46. M.A. Socinski, A.B. Sandler, L.M. Langdon Phase I trial of the combination of irinotecan, paclitaxel and carboplatin in patients with advanced non-small cell lung cancer J Clin Oncol 19 2001 1078
47. B. Movsas, C. Scott, C. Langer Phase III study of amifostine in patients with locally advanced non-small cell lung cancer (NSCLC) receiving chemotherapy and hyperfractionated radiation (chemo/HFxRT) Radiation Therapy Oncology Group (RTOG) 98-01 (abstr 2559) Proc Am Soc Clin Oncol 2003