A novel deprotection of trichloroacetamide

Tetrahedron Letters

Volumn 45, Issue 51, 2004, Pages 9405-9407

  Urabe, Daisuke ^a   Sugino, Kumi ^a   Nishikawa, Toshio ^a,b   Isobe, Minoru ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Deprotection; Overman rearrangement; Protecting group; Trichloroacetamide

Indexed keywords

CHLOROACETAMIDE; TRICHLOROACETAMIDE; UNCLASSIFIED DRUG;

DEPROTECTION REACTION; SHORT SURVEY;

EID: 8844231767     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.10.099     Document Type: Article

References (20)

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10. 3: C, 68.79; H, 9.02; N, 5.01. Found: C, 68.81; H, 9.01; N, 4.82
11. 3
12. 17 may be captured by the carbonate, giving the amine
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16. 13 and acetylation
17. 18 by trichloroacetylation in pyridine
18. The reaction conditions of these transformations have not been optimized
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