Protection by sustained release of physostigmine and procyclidine of soman poisoning in rats

European Journal of Pharmacology

Volumn 505, Issue 1-3, 2004, Pages 83-91

  Choi, Ehn Kyoung ^a   Park, Dongsun ^a   Yon, Jung Min ^a   Hur, Gyeung Haeng ^b   Ha, Yeon Cheol ^b   Che, Jeong Hwan ^b   Kim, Jongsun ^a   Shin, Sunhee ^a   Jang, Ja Young ^a   Hwang, Seock Yeon ^c   Seong, Yeon Hee ^a   Kim, Dae Joong ^a   Kim, Jong Choon ^d   Kim, Yun Bae ^a  

^a Chungbuk National University   (South Korea)

^b Agency for Defence Development   (South Korea)

^c Chungbuk National University College of Medicine   (South Korea)

^d Chonnam National University   (South Korea)

Author keywords

Brain injury; Memory impairment; Physostigmine; Procyclidine; Prophylactic; Soman

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ORGANOPHOSPHATE; PHYSOSTIGMINE; PROCYCLIDINE; SOMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICHOLINERGIC EFFECT; ARTICLE; BLOOD ANALYSIS; BLOOD BRAIN BARRIER; BRAIN INJURY; CONTROLLED STUDY; CONVULSION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; HEMOCONCENTRATION; INTERMETHOD COMPARISON; INTOXICATION; LEARNING; LETHALITY; MEMORY DISORDER; MORTALITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OSMOTIC MINIPUMP; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROPHYLAXIS; RAT; TASK PERFORMANCE;

ANIMALS; AVOIDANCE LEARNING; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARY PERMEABILITY; CHOLINESTERASE INHIBITORS; DELAYED-ACTION PREPARATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; INFUSION PUMPS; MALE; MEMORY; MUSCARINIC ANTAGONISTS; PHYSOSTIGMINE; PROCYCLIDINE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SOMAN; SPECIFIC PATHOGEN-FREE ORGANISMS; TIME FACTORS;

EID: 8844231017     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.10.034     Document Type: Article

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