Biodegradation behavior of gellan gum in simulated colonic media

Pharmaceutical Development and Technology

Volumn 9, Issue 4, 2004, Pages 399-407

  Singh, Brahma N ^a,b   Trombetta, Louis D ^a   Kim, Kwon H ^a  

^a ST JOHN'S UNIVERSITY   (United States)

^b Emisphere Technologies Inc   (United States)

Author keywords

Beads; Biodegradation; Controlled colonic delivery; Galactomannanase; Gellan gum; Ionotropic gelation

Indexed keywords

AZATHIOPRINE; BETA MANNOSIDASE; CALCIUM ION; EUDRAGIT; GALACTOMANNANASE; GELLAN; POLYMER; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; COLON; DEACETYLATION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME MECHANISM; FLOW KINETICS; GELATION; IN VITRO STUDY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SIMULATION; TIMED DRUG RELEASE; VISCOSITY;

AZATHIOPRINE; BIODEGRADATION, ENVIRONMENTAL; CHEMISTRY, PHARMACEUTICAL; COLON; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG EVALUATION, PRECLINICAL; GASTRIC JUICE; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MANNOSIDASES; MICROSCOPY, ELECTRON, SCANNING; POLYMETHACRYLIC ACIDS; POLYSACCHARIDES; POLYSACCHARIDES, BACTERIAL; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; VISCOSITY;

EID: 8744315407     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-200035793     Document Type: Article

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