Olfactory learning-induced increase in spine density along the apical dendrites of CA1 hippocampal neurons

Hippocampus

Volumn 14, Issue 7, 2004, Pages 819-825

  Knafo, Shira ^a   Ariav, Gal ^b   Barkai, Edi ^c   Libersat, Frederic ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c UNIVERSITY OF HAIFA   (Israel)

Author keywords

Plasticity; Pyramidal neurons; Rule learning; Synaptic connections

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BRAIN FUNCTION; BRAIN NERVE CELL; CELL DENSITY; CELL STRUCTURE; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; DISCRIMINATION LEARNING; GOLGI STAIN; HIPPOCAMPUS; MALE; MICROSCOPY; NERVE CELL STIMULATION; NONHUMAN; OLFACTORY DISCRIMINATION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; REWARD; STATE DEPENDENT LEARNING; SYNAPSE;

ANIMALS; COLORING AGENTS; CUES; DENDRITES; HIPPOCAMPUS; LEARNING; MALE; NEURAL PATHWAYS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SMELL; TISSUE FIXATION;

EID: 8744303813     PISSN: 10509631     EISSN: None     Source Type: Journal    
DOI: 10.1002/hipo.10219     Document Type: Article

References (31)

1. Alvarez P, Eichenbaum H. 2002. Representations of odors in the rat orbitofrontal cortex change during and after learning. Behav Neurosci 116:421-433.
2. Bunsey M, Eichenbaum H. 1996. Conservation of hippocampal memory function in rats and humans. Nature 379:255-257.
3. Dusek JA, Eichenbaum H. 1997. The hippocampus and memory for orderly stimulus relations. Proc Natl Acad Sci USA 94:7109-7114.
4. Eichenbaum H. 1998. Using olfaction to study memory. Ann NY Acad Sci 855:657-669.
5. Fiala JC, Harris KM. 1999. Dendrite structure. In: Stuart G, Spruston N, Hausser M, editors. Dendrites. Oxford UK: Oxford University Press.
6. Fiala JC, Feinberg M, Popov V, Harris KM. 1998. Synaptogenesis via dendritic filopodia in developing hippocampal area CA1. J Neurosci 18:8900-8911.
7. Geinisman Y, Berry RW, Disterhoft JF, Power JM, Van der Zee EA. 2001. Associative learning elicits the formation of multiple-synapse boutons. J Neurosci 21:5568-5573.
8. Guzowski JF. 2002. Insights into immediate-early gene function in hippocampal memory consolidation using antisense oligonucleotide and fluorescent imaging approaches. Hippocampus 12:86-104.
9. Haberly LB. 2001. Parallel-distributed processing in olfactory cortex: new insights from morphological and physiological analysis of neuronal circuitry. Chem Senses 26:551-576.
10. Hebb D. 1949. The organization of behavior. New York: John Wiley.
11. Hess US, Lynch G, Gall CM. 1995a. Regional patterns of c-fos mRNA expression in rat hippocampus following exploration of a novel environment versus performance of a well-learned discrimination. J Neurosci 15:7796-7809.
12. Hess US, Lynch G, Gall CM. 1995b. Changes in c-fos mRNA expression in rat brain during odor discrimination learning: differential involvement of hippocampal subfields CA1 and CA3. J Neurosci 15(7 Pt 1):4786-4795.
13. Kirov SA, Sorra KE, Harris KM. 1999. Slices have more synapses than perfusion-fixed hippocampus from both young and mature rats. J Neurosci 19:2876-2886.
14. Knafo S, Grossman Y, Barkai E, Benshalom G. 2001. Olfactory learning is associated with increased spine density along apical dendrites of pyramidal neurons in the rat piriform cortex. Eur J Neurosci 13:633-638.
15. Leuner B, Falduto J, Shors TJ. 2003. Associative memory formation increases the observation of dendritic spines in the hippocampus. J Neurosci 23:659-665.
16. Moser MB, Trommald M, Andersen P. 1994. An increase in dendritic spine density on hippocampal CA1 pyramidal cells following spatial learning in adult rats suggests the formation of new synapses. Proc Natl Acad Sci USA 91:12673-12675.
17. Moser MB, Trommald M, Egeland T, Andersen P. 1997. Spatial training in a complex environment and isolation alter the spine distribution differently in rat CA1 pyramidal cells. J Comp Neurol 380: 373-381.
18. O'Malley A, O'Connell C, Regan CM. 1998. Ultrastructural analysis reveals avoidance conditioning to induce a transient increase in hippocampal dentate spine density in the 6 hour post-training period of consolidation. Neuroscience 87:607-613.
19. O'Malley A, O'Connell C, Murphy KJ, Regan CM. 2000. Transient spine density increases in the mid-molecular layer of hippocampal dentate gyrus accompany consolidation of a spatial learning task in the rodent. Neuroscience 99:229-232.
20. Otmakhova NA, Otmakhov N, Lisman JE. 2002. Pathway-specific properties of AMPA and NMDA-mediated transmission in CA1 hippocampal pyramidal cells. J Neurosci 22:1199-1207.
21. Robinson TE, Gorny G, Savage VR, Kolb B. 2002. Widespread but regionally specific effects of experimenter- versus self-administered morphine on dendritic spines in the nucleus accumbens, hippocampus, and neocortex of adult rats. Synapse 46:271-279.
22. Saar D, Grossman Y, Barkai E. 1998. Reduced after-hyperpolarization in rat piriform cortex pyramidal neurons is associated with increased learning capability during operant conditioning. Eur J Neurosci 10: 1518-1523.
23. Saar D, Grossman Y, Barkai E. 1999. Reduced synaptic facilitation between pyramidal neurons in the piriform cortex after odor learning. J Neurosci 19:8616-8622.
24. Saar D, Grossman Y, Barkai E. 2001. Long-lasting cholinergic modulation underlies rule learning in rats. J Neurosci 21:1385-1392.
25. Saar D, Grossman Y, Barkai E. 2002. Learning-induced enhancement of postsynaptic potentials in pyramidal neurons. J Neurophysiol 87:2358-2363.
26. Shankaranarayana Rao BS, Raju TR, Meti BL. 1999. Self-stimulation rewarding experience induced alterations in dendritic spine density in CA3 hippocampal and layer V motor cortical pyramidal neurons. Neuroscience 89:1067-1077.
27. Sorra KE, Harris KM. 2000. Overview on the structure, composition, function, development, and plasticity of hippocampal dendritic spines. Hippocampus 10:501-511.
28. Squire LR. 1992. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol Rev 99:195-231.
29. Staubli U, Fraser D, Faraday R, Lynch G. 1987. Olfaction and the "data" memory system in rats. Behav Neurosci 101:757-765.
30. Trommald M, Jensen V, Andersen P. 1995. Analysis of dendritic spines in rat CA1 pyramidal cells intracellularly filled with a fluorescent dye. J Comp Neurol 353:260-274.
31. Valverde F. 1970. The Golgi method. A tool for comparative structural analyses. In: Nauta WJH, Ebbesson SOE, editors. Contemporary research methods in neuroanatomy. New York: Springer-Verlag. p 12-31.