Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase

Journal of Medicinal Chemistry

Volumn 47, Issue 24, 2004, Pages 5860-5871

  Rosen, Thomas C ^a   Yoshida, Shinichi ^b,c   Fröhlich, Roland ^a   Kirk, Kenneth L ^b   Haufe, Günter ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c Industrial Research Institute   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 FLUORO 2 PHENYLCYCLOPROPYLAMINE; AMINE OXIDASE (FLAVIN CONTAINING); MONOAMINE OXIDASE INHIBITOR; TRANYLCYPROMINE; UNCLASSIFIED DRUG;

ARTHROBACTER; ARTICLE; CIS TRANS ISOMERISM; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIASTEREOISOMER; DRUG CONFORMATION; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; ELECTRON TRANSPORT; ENANTIOMER; ENZYME INHIBITION; IC 50; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ARTHROBACTER; CRYSTALLOGRAPHY, X-RAY; MOLECULAR STRUCTURE; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PROPYLAMINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANYLCYPROMINE;

EID: 8644286277     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049957t     Document Type: Article

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