Should etomidate be the induction agent of choice for rapid sequence intubation in the emergency department?

Emergency Medicine Journal

Volumn 21, Issue 6, 2004, Pages 655-659

  Oglesby, Angela J ^a  

^a ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CORTICOSTEROID DERIVATIVE; ETOMIDATE; FENTANYL; HYDROCORTISONE; KETAMINE; LIDOCAINE; MIDAZOLAM; OPIATE DERIVATIVE; PROPOFOL; SUXAMETHONIUM; TETRACOSACTIDE; THIOPENTAL; TUBOCURARINE CHLORIDE; VECURONIUM;

ADRENAL CORTEX DISEASE; ADRENAL CORTEX FUNCTION; ADRENAL DISEASE; ADRENAL INSUFFICIENCY; ANESTHESIA; ANESTHESIA INDUCTION; BREATHING DISORDER; CARDIOVASCULAR DISEASE; CLINICAL OBSERVATION; CLINICAL STUDY; CLINICAL TRIAL; COCHRANE LIBRARY; DOSE RESPONSE; DRUG FATALITY; EMBASE; EMERGENCY HEALTH SERVICE; EMERGENCY MEDICINE; EMERGENCY WARD; ENDOTRACHEAL INTUBATION; HEMODYNAMICS; HUMAN; HYPERTENSION; HYPOTENSION; HYPOVOLEMIA; INJECTION PAIN; MEDICAL LITERATURE; MEDICAL RESEARCH; MEDLINE; MYOCLONUS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; SOMNOLENCE; TACHYCARDIA;

ADRENAL CORTEX HORMONES; ANESTHETICS, INTRAVENOUS; CEREBROVASCULAR CIRCULATION; EMERGENCIES; EMERGENCY TREATMENT; ETOMIDATE; HEMODYNAMIC PROCESSES; HUMANS; INTUBATION, INTRATRACHEAL;

EID: 8644281114     PISSN: 14720205     EISSN: None     Source Type: Journal    
DOI: 10.1136/emj.2003.009043     Document Type: Review

References (54)

1. Walls RM. Rapid sequence intubation. In: Walls RM, Luten RC, Murphy MF, et al, eds, Manual of emergency airway management. Philadelphia: Lippincott, Williams and Wilkins, 2000:8-15.
2. Walls RM, Vissers RJ, Sagarin MJ, et al. Emergency department intubations-final report of the National Emergency Airway Registry Pilot Project. [Abstract]. J Accid Emerg Med 1998;15:392.
3. Sakles JC, Laurin EG, Rantapaa AA, et al. Airway management in the emergency department: a one-year study of 610 tracheal intubations. Ann Emerg Med 1998;31:325-32.
4. Dufour DG, Larose DL, Clement SC. Rapid sequence intubation in the emergency department. J Emerg Med 1995;13 705-10.
5. Tayal VS, Riggs RW, Marx JA, et al. Rapid-sequence intubation at an emergency medicine registry: success rate and adverse events during a two year period. Acad Emerg Med 1999; 6:31-7.
6. Ligier BL, Buchman TG, Breslow MJ, et al. The role of anestheic induction agents and neuromuscular blockade in the endotracheal intubation of trauma patients. Surg Gynecol Obstetr 1991;173:477-81.
7. Li J, Murphy-Lavoie H, Bugas C, et al. Complications of emergency intubation with and without paralysis. Am J Emerg Med 1999;17:141-3.
8. Graham CA, Beard D, Oglesby AJ, et al. Rapid sequence intubation in Scottish urban emergency departments. Emerg Med J 2003;20:3-5.
9. Morris J, Cook TM. Rapid sequence induction: a national survey of practice. Anaesthesia 2001;56:1090-15.
10. Wadbrook PS. Advances in airway pharmacology - emerging trends and evolving controversy. Emerg Med Clin N Am 2000; 18 767-88.
11. Clarke RSJ. Intravenous anaesthetic agents. In: Healy EJ, Cohen PJ, eds. A practice of anaesthesia. London: Wylie and Churchill-Davidson, 1995:169-83.
12. Schneider RE. Sedatives and induction agents. In: Walls RM, Luten RC, Murphy MF, et al. eds. Manual of emergency airway management. Philadelphia: Lippincott, Williams and Wilkins, 2000:129-34.
13. Talucci RC, Shaikh KA, Schwab CW. Rapid sequence induction with oral endotracheal intubation in the multiply injured patient. Am Surg 1988;54:185-7.
14. Ampel L, Hott KA, Sielaff GW, et al. An approach to airway management in the acutely head-injured patient. J Emerg Med 1988;6:1-7.
15. Vohra A, Thomas AN, Harper NJ, et al. Non-invasive measurement of cardiac output during induction of anaesthesia and tracheal intubation. Thiopentone and propofol compared. Br J Anaesth 1991;67:64-8.
16. Splinter WM, Cervenko F. Haemodynamic responses to laryngoscopy and tracheal intubation in geriatric patients: Effects of fentanyl, lidocaine and thiopentone. Can J Anaesth 1989;36 370-6.
17. Rotondo MF, McGonigal MD, Schwab CW, et al. Urgent paralysis and intubation of trauma patients: Is it safe? J Trauma 1993;34:242-6.
18. Harsten A, Gillberg L. Intubating conditions provided by propofol and alfentanil - acceptable, but not ideal. Acta Anaesth Scand 1997;41:985-7.
19. Kazama T, Ikeda K, Morita K, et al. Propofol concentration required for endotracheal intubation with a laryngoscope or fiberscope and its interaction with fentanyl. Anesth Analg 1998; 86:872-9.
20. Skinner HJ, Biswas A, Mahajan RP. Evaluation of intubating conditions with rocuronium and either propofol or etomidate for rapid sequence induction. Anaesthesia 1998;53:702-10.
21. Wong AK, Teoh GS. Intubation without muscle relaxant: an alternative technique for rapid tracheal intubation. Anaesth Intensive Care 1996;24:224-30.
22. El-Beheiry H, Milne B, Seegobin R. Prophylaxis against the systemic hypotension induced by propofol during rapid-sequence intubation. Can J Anaesth 1995;42:875-8.
23. Gooding JM, Weng JT, Smith RA, et al. Cardiovascular and pulmonary responses following etomidate induction of anesthesia in patients with demonstrated cardiac disease. Anesth Analg 1979;58:40-1.
24. Moss E, Powell D, Gibson RM, et al. Effect of etomidate on intracranial pressure and cerebral perfusion pressure. Br J Anaesth 1979;51:347-52.
25. Wagner RL, White PF, Kan PB, et al. Inhibition of adrenal steroidogenesis by the anesthetic etomidate. N Engl J Med 1984;310:1415-21.
26. Fellows IW, Bastow MD, Byrne AJ, et al. Adrenocortical suppression in multiply injured patients: a complication of etomidate treatment. BMJ 1983;287:1835-7.
27. Smith DC, Smithline HA. Intubation practice in US EDs. Ann Emerg Med 1997;30:401.
28. Smith DC, Bergen JM, Smithline H, et al. A trial of etomidate for rapid sequence intubation in the emergency department. J Emerg Med 2000;18:13-16.
29. Swanson ER, Fosnocht DE, Renee J, et al. The use of etomidate for rapid sequence intubation in the air medical setting. Prehosp Emerg Care 2001;5:142-6.
30. Sokolove PE. The safety of etomidate for emergency rapid sequence intubation of pediatric patients. Pediatr Emerg Care 2000;16:18-21.
31. Schenarts CL, Burton JH, Riker RR. Adrenocortical dysfunction following etomidate induction in emergency department patients. Acad Emerg Med 2001;8:1-7.
32. Sivilotti MLA, Ducharme J. Randomised, double-blind study on sedatives and hemodynamics during rapid-sequence intubation in the emergency department: the SHRED study. Ann Emerg Med 1998; 31 313-23.
33. Woodward LL, Wolfson AB, lorg EC, et al. Hemodynamic effects of etomidate for rapid sequence intubation in emergency department trauma patients. [Abstract]. Acad Emerg Med 1995;2:406-7.
34. Johnson DM, King RW, Bohnett M. The safety and efficacy of etomidate as an adjunct to endotracheal intubation in the emergency department. [Abstract]. Acad Emerg Med 1994;1:318-19.
35. Laurin EG, Sackles JC, Prosser B, et al. The safety of etomidate for rapid-sequence intubation. [Abstract]. Acad Emerg Med 1996;3:527.
36. Plewa MC, King R, Johnson D, et al. Etomidate use during emergency intubation of trauma patients. Am J Emerg Med 1997;15:98-9.
37. Choi YF, Wong TW, Lau CC. Midazolam is more likely to cause hypotension than etomidate when used as induction agent for emergency rapid sequence intubation. [Abstract]. Emerg Med J 2002;19(suppl I):A21.
38. Bergen JM, Smith DC. A review of etomidate for rapid sequence intubation in the emergency department. J Emerg Med 1997;15:221-30.
39. Reves JG, Glass PSA, Lubarsky DA. Non-barbiturate intravenous anesthetics. In: Miller RD, ed. Anesthesia. New York: Churchill Livingstone, 2000:247-89.
40. Fuchs-Buder T, Sparr HJ, Ziegenfuss T. Thiopental or etomidate for rapid sequence induction with rocuronium. Br J Anaesth 1998;80:504-6.
41. Weiss-Bloom LJ, Reich DL. Haemodynamic responses to tracheal intubation following etomidate and fentanyl for anaesthetic induction. Can J Anaesth 1992;39:780-5.
42. Gooding JM, Corssen G. Etomidate: an ultrashort-acting non barbiturate agent for anesthesia induction. Anesth Analg 1976;55:286-9.
43. McCollum JS, Dundee JW. Comparison of induction characteristics of four intravenous anaesthetic agents. Anaesthesia 1986;41:995-1000.
44. Harris CE, Murray AM, Anderson JM, et al. Effects of thiopental, etomidate and propofol on the haemodynamic response to tracheal intubation. Anaesthesia 1988;43(suppl):32-6.
45. Waterman PM, Bjerke R. Rapid-sequence induction technique in patients with severe ventricular dysfunction. J Cardiothorac Anesth 1988;2:602-6.
46. Schulte AM, Esch J, Pfeifer G, et al. Effects of etomidate and thiopentone on the primarily elevated intracranial pressure (ICP). Anaesthetist 1978;27:71-5.
47. Cunitz G, Danhauser I, Wickbold J. Comparative investigations of the influence of etomidate, thiopentone and methohexitone on the intracranial pressure of the patient. Anaesthetist 1978;27:64-70.
48. Ledingham IM, Watt I. Influence of sedation on mortality in critically ill trauma patients. [Letter]. Lancet 1983;i:1270.
49. Ledingham IM, Finlay WE, Watt I, et al. Etomidate and adrenocortical function. [Letter]. Lancet 1983;i:1434.
50. Duthie D, Fraser R, Nimmo W. Effect of induction of anaesthesia with etomidate on coricosteroid synthesis in man. Br J Anaesth 1985;57:156-9.
51. Sebel PS, Verghese C, Makin HLJ. Effect on plasma cortisol concentrations of a single induction dose of etomidate or thiopentone. Lancet 1983;ii:625.
52. Fragen RJ, Shanks CA, Molteni A. Effect on plasma cortisol concentrations of a single induction dose of etomidate or thiopentone. Lancet 1983;ii:625-6.
53. Holdcroft A, Morgan M, Whitman JG, et al. Effect of dose and premedication on induction complications with etomidate. Br J Anaesth 1976;48:199-205.
54. Scottish Intercollegiate Guidelines Network. Levels of evidence. http://www.sign.ac.uk (accessed 1 Aug 2002).