Altered inactivation of Ca2- current and Ca2+ release in mouse muscle fibers deficient in the DHP receptor γ1 subunit

Journal of General Physiology

Volumn 124, Issue 5, 2004, Pages 605-618

  Ursu, Daniel ^a   Schuhmeier, Ralph Peter ^a   Freichel, Marc ^b   Flockerzi, Veit ^b   Melzer, Werner ^a  

^a UNIVERSITY OF ULM   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Accessory subunits; Excitation contraction coupling; Knockout mouse; Mammalian skeletal muscle; Voltage dependent inactivation

Indexed keywords

1,4 DIHYDROPYRIDINE RECEPTOR; CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM ION; DIHYDROPYRIDINE RECEPTOR GAMMA1; POLYPEPTIDE; POTASSIUM; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; CALCIUM; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); ELECTRIC POTENTIAL; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MOUSE; MUSCLE CELL; MUSCLE FORCE; MYOTUBE; NONHUMAN; PROTEIN EXPRESSION; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; VOLTAGE CLAMP; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; DRUG EFFECT; MECHANICAL STRESS; METABOLISM; MOUSE MUTANT; MUSCLE CONTRACTION; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; ION CHANNEL GATING; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MUSCLE CONTRACTION; MUSCLE FIBERS; MUSCLE, SKELETAL; POTASSIUM; PROTEIN SUBUNITS; SARCOPLASMIC RETICULUM; STRESS, MECHANICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 8644269579     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409168     Document Type: Article

References (57)

1. 2+ release by the γ1 subunit of the dihydropyridine receptor of skeletal muscle. BMC Physiol. 1:8.
2. Arikkath, J., and K.P. Campbell. 2003. Auxiliary subunits: essential components of the voltage-gated calcium channel complex. Curr. Opin. Neurobiol. 13:298-307.
3. Baylor, S.M., W.K. Chandler, and M.W. Marshall. 1983. Sarcoplasmic reticulum calcium release in frog skeletal muscle fibres estimated from Arsenazo III calcium transients. J. Physiol. 344:625-666.
4. Baylor, S.M., and S. Hollingworth. 2003. Sarcoplasmic reticulum calcium release compared in slow-twitch and fast-twitch fibres of mouse muscle. J. Physiol. 551:125-138.
5. Bers, D.M. 2001. Excitation-Contraction Coupling and Cardiac Contractile Force. Kluver Academic Publishers, Dordrecht, The Netherlands. 427 pp.
6. Berwe, D., G. Gottschalk, and H.C. Lüttgau. 1987. Effects of the calcium antagonist gallopamil (D600) upon excitation-contraction coupling in toe muscle fibres of the frog. J. Physiol. 385:693-707.
7. Biel, M., R. Hullin, S. Freundner, D. Singer, N. Dascal, V. Flockerzi, and F. Hofmann. 1991. Tissue-specific expression of high-voltage-activated dihydropyridine-sensitive L-type calcium channels. Eur. J. Biochem. 200:81-88.
8. Bosse, E., S. Regulla, M. Biel, P. Ruth, H.E. Meyer, V. Flockerzi, and F. Hofmann. 1990. The cDNA and deduced amino acid sequence of the γ subunit of the L-type calcium channel from rabbit skeletal muscle. FEBS Lett. 267:153-156.
9. Brum, G., E. Rios, and E. Stefani. 1988. Effects of extracellular calcium on calcium movements of excitation-contraction coupling in frog skeletal muscle fibres. J. Physiol. 398:441-473.
10. Caputo, C., and P. Bolanos. 1987. Contractile inactivation in frog skeletal muscle fibers. The effects of low calcium, tetracaine, dantrolene, D-600, and nifedipine. J. Gen. Physiol. 89:421-442.
11. Caputo, C., and B. Fernandez. 1979. Membrane potential, contractile activation and relaxation rates in voltage clamped short muscle fibres of the frog. J. Physiol. 289:175-189.
12. Chen, L., D.M. Chetkovich, R.S. Petralia, N.T. Sweeney, Y. Kawasaki, R.J. Wenthold, D.S. Bredt, and R.A. Nicoll. 2000. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature. 408:936-943.
13. Cheung, A., J.A. Dantzig, S. Hollingworth, S.M. Baylor, Y.E. Goldman, T.J. Mitchison, and A.F. Straight. 2002. A small-molecule inhibitor of skeletal muscle myosin II. Nat. Cell Biol. 4:83-88.
14. Chua, M., and A.F. Dulhunty. 1988. Inactivation of excitation-contraction coupling in rat extensor digitorum longus and soleus muscles. J. Gen. Physiol. 91:737-757.
15. Chua, M., and A.F. Dulhunty. 1989. Noninactivating tension in rat skeletal muscle. Effects of thyroid hormone. J. Gen. Physiol. 94:183-203.
16. Csernoch, L., P. Szentesi, and L. Kovacs. 1999a. Differential effects of caffeine and perchlorate on excitation-contraction coupling in mammalian skeletal muscle. J. Physiol. 520:217-230.
17. Csernoch, L., P. Szentesi, S. Sarkozi, C. Szegedi, I. Jona, and L. Kovacs. 1999b. Effects of tetracaine on sarcoplasmic calcium release in mammalian skeletal muscle fibres. J. Physiol. 515:843-857.
18. Dirksen, R.T. 2002. Bi-directional coupling between dihydropyridine receptors and ryanodine receptors. Front. Biosci. 7:d659-d670.
19. Dulhunty, A.F. 1991. Activation and inactivation of excitation- contraction coupling in rat soleus muscle. J. Physiol. 439:605-626.
20. Eberst, R., S. Dai, N. Klugbauer, and F. Hofmann. 1997. Identification and functional characterization of a calcium channel γ subunit. Pflügers Arch. 433:633-637.
21. 2+ current in isolated frog skeletal muscle fibres. J. Physiol. 413:521-541.
22. Feldmeyer, D., W. Melzer, and B. Pohl. 1990. Effects of gallopamil on calcium release and intramembrane charge movements in frog skeletal muscle fibres. J. Physiol. 421:343-362.
23. 2+ currents and alters channel inactivation properties. J. Biol. Chem. 275:14476-14481.
24. Garcia, J., and M.F. Schneider. 1993. Calcium transients and calcium release in rat fast-twitch skeletal muscle fibres. J. Physiol. 463:709-728.
25. Gonzalez, A., and E. Rios. 1993. Perchlorate enhances transmission in skeletal muscle excitation-contraction coupling. J. Gen. Physiol. 102:373-421.
26. 2+ current modulation in γ1-deficient and wildtype murine myotubes by the γ1 subunit and cAMP. J. Physiol. 539:459-468.
27. Jacquemond, V. 1997. Indo-1 fluorescence signals elicited by membrane depolarization in enzymatically isolated mouse skeletal muscle fibers. Biophys. J. 73:920-928.
28. Jay, S.D., S.B. Ellis, A.F. McCue, M.E. Williams, T.S. Vedvick, M.M. Harpold, and K.P. Campbell. 1990. Primary structure of the γ subunit of the DHP-sensitive calcium channel from skeletal muscle. Science. 248:490-492.
29. Jong, D.S., P.C. Pape, W.K. Chandler, and S.M. Baylor. 1993. Reduction of calcium inactivation of sarcoplasmic reticulum calcium release by fura-2 in voltage-clamped cut twitch fibers from frog muscle. J. Gen. Physiol. 102:333-370.
30. Joumaa, W.H., and C. Leoty. 2002. A comparative analysis of the effects of exercise training on contractile responses in fast- and slow-twitch rat skeletal muscles. J. Comp. Physiol. [B] 172:329-338.
31. Klein, M.G., B.J. Simon, G. Szücs, and M.F. Schneider. 1988. Simultaneous recording of calcium transients in skeletal muscle using high- and low-affinity calcium indicators. Biophys. J. 53:971-988.
32. Lamb, G.D. 1992. DHP receptors and excitation-contraction coupling. J. Muscle Res. Cell Motil. 13:394-405.
33. Lerche, H., N. Klugbauer, F. Lehmann-Horn, F. Hofmann, and W. Melzer. 1996. Expression and functional characterization of the cardiac L-type calcium channel carrying a skeletal muscle DHP-receptor mutation causing hypokalaemic periodic paralysis. Pflügers Arch. 431:461-463.
34. Melzer, W., E. Rios, and M.F. Schneider. 1984. Time course of calcium release and removal in skeletal muscle fibers. Biophys. J. 45:637-641.
35. Melzer, W., E. Ríos, and M.F. Schneider. 1986. The removal of myoplasmic free calcium following calcium release in frog skeletal muscle. J. Physiol. 372:261-292.
36. Melzer, W., E. Ríos, and M.F. Schneider. 1987. A general procedure for determining the rate of calcium release from the sarcoplasmic reticulum in skeletal muscle fibers. Biophys. J. 51:849-863.
37. 2+ ions in excitation-contraction coupling of skeletal muscle fibres. Biochim. Biophys. Acta. 1241:59-116.
38. 2+ current in frog skeletal muscle fibres. J. Physiol. 427:187-209.
39. 2+ channels. In The Calcium Channel, Structure, Function, and Implications. M. Morad, W. Nayler, S. Kazda, and M. Schramm, editors. Springer Verlag, Berlin. 138-158.
40. 2+ channel (CACNLG), cDNA sequence, gene structure, and chromosomal location. J. Biol. Chem. 268:9275-9279.
41. Ríos, E., and G. Brum. 1987. Involvement of dihydropyridine receptors in excitation-contraction coupling in skeletal muscle. Nature. 325:717-720.
42. Ríos, E., and G. Pizarro. 1991. Voltage sensor of excitation-contraction coupling in skeletal muscle. Physiol. Rev. 71:849-908.
43. Schneider, M.F., and B.J. Simon. 1988. Inactivation of calcium release from the sarcoplasmic reticulum in frog skeletal muscle. J. Physiol. 405:727-745.
44. Schneider, M.F., B.J. Simon, and G. Szücs. 1987. Depletion of calcium from the sarcoplasmic reticulum during calcium release in_ frog skeletal muscle. J. Physiol. 392:167-192.
45. Schnier, A., H.C. Lüttgau, and W. Melzer. 1993. Role of extracellular metal cations in the potential dependence of force inactivation qin skeletal muscle fibres. J. Muscle Res. Cell Motil. 14:565-572.
46. 2+ fluxes in skeletal myotubes determined using a removal model analysis. J. Gen. Physiol. 123:33-51.
47. Schuhmeier, R.P., B. Dietze, D. Ursu, F. Lehmann-Horn, and W. Melzer. 2003. Voltage-activated calcium signals in myotubes loaded with high concentrations of EGTA. Biophys. J. 84:1065-1078.
48. Shaw, M.A., E.M. Ostap, and Y.E. Goldman. 2003. Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluene-sulfonamide. Biochemistry. 42:6128-6135.
49. 2+ release from the sarcoplasmic reticulum compared in amphibian and mammalian skeletal muscle. J. Gen. Physiol. 107:1-18.
50. Simon, B.J., M.G. Klein, and M.F. Schneider. 1991. Calcium dependence of inactivation of calcium release from the sarcoplasmic reticulum in skeletal muscle fibers. J. Gen. Physiol. 97:437-471.
51. Singer, D., M. Biel, I. Lotan, V. Flockerzi, F. Hofmann, and N. Dascal. 1991. The roles of the subunits in the function of the calcium channel. Science. 253:1553-1557.
52. 2+ channels. Pflügers Arch. 439:691-699.
53. 2+ transients in skeletal muscle deficient in dihydropyridine receptor β1 subunit. Biophys. J. 71:2531-2543.
54. Ursu, D., S. Sebille, B. Dietze, D. Freise, V. Flockerzi, and W. Melzer. 2001. Excitation-contraction coupling in skeletal muscle of a mouse lacking the dihydropyridine receptor subunit γ1. J. Physiol. 533:367-377.
55. 2+ channels: role in channel function. Trends Neurosci. 21:148-154.
56. 2+ channels. J. Biol. Chem. 266:21943-21947.
57. Wissenbach, U., E. Bosse-Doenecke, D. Freise, A. Ludwig, M. Murakami, F. Hofmann, and V. Flockerzi. 1998. The structure of the murine calcium channel γ-subunit gene and protein. Biol. Chem. 379:45-50.