Synthesis of C-13 oxidised cuparene and herbertane sesquiterpenes via a Paternò-Büchi photocyclisation-oxetane fragmentation strategy: Total synthesis of 1,13-herbertenediol

Synlett

Volumn , Issue 13, 2004, Pages 2379-2381

  Boxall, Richard J ^a   Ferris, Leigh ^b   Grainger, Richard S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Fused ring systems; Photochemistry; Reduction; Ring opening; Terpenoids

Indexed keywords

1,13 HERBERTENEDIOL; CUPARENE; CYCLOPENTANE; HERBERTANE; METHYL GROUP; OXETANE DERIVATIVE; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; CYCLIZATION; PATERNO BUCHI REACTION; PHOTOCHEMISTRY; SYNTHESIS;

EID: 8644243047     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-832813     Document Type: Article

References (29)

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29. 4 and concentrated in vacuo to furnish a pale yellow oil. The crude product was purified by column chromatography (hexane-EtOAc 9:1) to afford 1,13-herbertenediol as a colourless oil (29 mg, 77%). Analytic data agree with those reported in the literature.