Glomerular endothelial dysfunction, altered hemorheology and hemodynamic maladjustment in nephrosis with focal segmental glomerulosclerosis

Hong Kong Journal of Nephrology

Volumn 6, Issue 2, 2004, Pages 69-73

  Futrakul, Narisa ^a   Sitprija, Visith ^a   Siriviriyaku, Prasong ^a   Futrakul, Prasit ^a  

^a KING CHULALONGKORN MEMORIAL HOSPITAL   (Thailand)

Author keywords

Glomerular endothelial dysfunction; Hemodynamic maladjustment; Immunocirculatory disturbance; Renal perfusion; Vasodilators

Indexed keywords

ANTITHROMBOCYTIC AGENT; VASCULOTROPIN; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

ANTICOAGULATION; ARTERIOLE; ARTERY CONSTRICTION; BASEMENT MEMBRANE; BLOOD RHEOLOGY; CAPILLARY FLOW; DISEASE COURSE; DISEASE EXACERBATION; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; FIBROGENESIS; FOCAL GLOMERULOSCLEROSIS; GLOMERULUS EPITHELIUM; GLOMERULUS FILTRATION RATE; HUMAN; HYDROSTATIC PRESSURE; HYPERCOAGULABILITY; HYPERVISCOSITY SYNDROME; ISCHEMIA; KIDNEY BLOOD FLOW; KIDNEY FIBROSIS; KIDNEY FUNCTION; NEPHROSIS; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PODOCYTE; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEINURIA; REVIEW; ULTRAFILTRATION; VASODILATATION;

EID: 8644240162     PISSN: 15615413     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1561-5413(09)60161-7     Document Type: Review

References (53)

1. Laflam PF, Haraguchi S, Garin EH. Cytokine mRNA profile in lipoid nephrosis: evidence for increased IL-18 mRNA stability. Nephron 2002;91:620-6.
2. Matsumoto K, Kanmatsuse K. Augmented interleukin-18 production by peripheral monocytes in patients with minimal-change nephrotic syndrome. Am J Nephrol 2001;21:20-7.
3. Futrakul N, Butthep P, Patumraj S, Tipprukmas N, Futrakul P. Enhanced tumor necrosis factor in the serum and renal hypoperfusion in nephrosis associated with focal segmental glomerulosclerosis. Ren Fail 2000;22:213-7.
4. Lama G, Luongo I, Tirino G, Borriello A, Carangio C, Salsano ME. T-lymphocyte populations and cytokines in childhood nephrotic syndrome. Am J Kidney Dis 2002;39:958-65.
5. Matsumoto K, Kanmatsuse K. Interleukin-18 and interleukin-12 synergize to stimulate the production of vascular permeability factor by T-lymphocytes in normal subjects and in patients with minimal-change nephrotic syndrome. Nephron 2000;85:127-33.
6. Matsumoto K, Kanmatsuse K. Interleukin-15 and interleukin-12 have an additive effect on the release of vascular permeability factor by peripheral blood mononuclear cells in normals and in patients with nephrotic syndrome. Clin Nephrol 1999; 52:8-10.
7. Sahali D, Pawlak A, Le-Gouvello S, Lang P, Valanciute A, Remy P, et al. Transcriptional and post-transcriptional alterations of IkappaBalpha in active minimal-change nephrotic syndrome. J Am Soc Nephrol 2001;12:1648-58.
8. Futrakul N, Tosukhowong P, Valyapongpichit Y, Tipprukmas N, Futrakul P, Patumraj S. Oxidative stress and hemodynamic maladjustment in chronic renal disease: a therapeutic implication. Ren Fail 2002;24:433-45.
9. Naga M, Honda N, Yoshitoshi Y. Effect of dipyridamole on glomerular negative charge in nephrotic rats induced by aminonucleoside. VIII International Congress of Nephrology, Athens, June 1981, Abstract book:239.
10. Futrakul P, Poshyachinda M, Mitrakul C. Hypercoagulability in the nephrotic syndrome: use of anticoagulant. In: Zurukzoglu W, Papadimitrio M, Pyrpasopoulos M, Sion M, Zamboulis C (eds). Advances in Basic Nephrology: Proceedings of the 8th International Congress of Nephrology, Athens. Basel: Karger, 1981:297-301.
11. Futrakul P, Poshyachinda M, Mitrakul C. Focal sclerosing glomerulonephritis: a kinetic evaluation of hemostasis and the effect of anticoagulant therapy: a controlled study. Clin Nephrol 1978;10:180-6.
12. Adhikari M, Coovadia HM, Greig HB, Christensen S. Factor VIII procoagulant activity in children with nephrotic syndrome and poststreptococcal glomerulonephritis. Nephron 1978;22:301-5.
13. Llach F. Hypercoagulability, renal vein thrombosis and other thrombotic complications of nephrotic syndrome. Kidney Int 1985;28:429-39.
14. Futrakul P, Poshyachinda V, Poshyachinda M, Sitprija V, Mitrakul C, Kankeerati V. Nephrotic syndrome: a kinetic evaluation of hemostasis and anticoagulant therapy in children. J Med Assoc Thai 1978;61:309-18.
15. Duffy JL, Cinque T, Grishman E, Churg J. Intraglomerular fibrin, platelet aggregation and subendothelial deposit in lipoid nephrosis. J Clin Invest 1970;49:251-6.
16. Futrakul P, Surichamorn P, Cherdboonchart V. Serum and urinary fibrin degradation product in Thai renal patients. J Med Assoc Thai 1974;57:346-50.
17. Stiehm ER, Kuplic LS, Nehling DT. Urinary fibrin split products in human renal disease. J Lab Clin Med 1971;77:843-7.
18. Cechin E, De Marchi S, Panarello G, De Augelio V. Rheological abnormalities of erythrocyte deformability and increased glycosylation of hemoglobin in the nephrotic syndrome. Am J Nephrol 1987;7:18-21.
19. Zwaginga JJ, Koomans HA, Sixma JJ, Rabelink AJ. Thrombus formation and platelet vessel wall interaction in the nephrotic syndrome and flow conditions. J Clin Invest 1994;93:204-11.
20. Futrakul N, Futrakul P, Poshyachinda M, Apaiwong S, Sensirivatana R, Thamaree S, et al. Intrarenal hemodynamic alteration in mesangial proliferative nephrotic syndrome with steroid resistance: effects of vasodilators. Nephron 1994;66:366-7.
21. Futrakul P, Sitprija V, Yenrudi S, Poshyachinda M, Sensirivatana R, Watana D, et al. Glomerular endothelial dysfunction determines disease progression: a hypothesis. Am J Nephrol 1997;17:533-40.
22. Futrakul P, Poshyachinda M, Yenrudi S, Saleekul P, Sensirivatana R, Futrakul N, et al. Intrarenal hemodynamic abnormality in severe form of glomerulonephritis: therapeutic benefit with vasodilators. J Med Assoc Thai 1992;75:375-85.
23. Futrakul N, Panichakul T, Chaisuriya P, Sirisinha S, Patumraj S, Futrakul P. Endothelial cell cytotoxicity and renal hypoperfusion in idiopathic nephrotic syndrome. Nephron 2000;86:241-2.
24. Kriz W, Elger M, Nagata M, Kretzler M, Uiker S, Koeppen-Hageman I, et al. The role of podocytes in the development of glomerulosclerosis. Kidney Int Suppl 1994;45:64-72.
25. Rennke HG. How does glomerular epithelial cell injury contribute to progressive glomerular damage? Kidney Int Suppl 1994;45:58-63.
26. Fan L, Wakayama T, Yokoyama S, Amano O, Iseki S. Downregulation of vascular endothelial growth factor and its receptors in the kidney in rats with puromycin aminonucleoside nephrosis. Nephron 2002;90:95-102.
27. Kang DH, Kanellis J, Hugo C, Truong L, Anderson S, Kerjaschki D, et al. Role of microvascular endothelium in progressive renal disease. J Am Soc Nephrol 2002;13:806-16.
28. Kang DH, Joly AH, Oh SE, Hugo C, Kerjaschki D, Gordon KL, et al. Impaired angiogenesis in the remnant kidney model: I. Potential role of vascular endothelial growth factor and thrombospondin-1. J Am Soc Nephrol 2001;12:1434-47.
29. Futrakul N, Kittikowit W, Yenrudi S. Reduced endothelial factor VIII staining in renal microcirculation correlates with hemodynamic alteration in nephrosis. Ren Fail 2003;25:759-64.
30. Wei Z, Costa K, Al-Medhi AB, Dodia C, Muzykantor V, Fisher AB. Simulated ischemia in flow-adapted endothelial cells leads to generation of reactive oxygen species and cell signaling. Circ Res 1999;85:682-9.
31. Malek AM, Gibbons GH, Dzau VJ, Izumo S. Fluid shear stress differentially modulates expression of gene encoding basic fibroblast growth factor and platelet derived growth factor B-chain in vascular endothelium. J Clin Invest 1993;92:2013-21.
32. Nagel T, Resnick N, Atkinson WJ, Dewey CF, Gimbrone MA Jr. Shear stress upregulates functional ICAM-1 expression in cultured vascular endothelial cells. FASEB J 1993;7:A2. (Abstract)
33. Malek AM, Izumo J. Molecular aspects of signal transduction of shear stress in the endothelial cell. J Hypertens 1994;12:989-1000.
34. Frangos JA, Estain SG, McIntire LV, Ives CL. Flow effects on prostacyclin production by cultured human endothelial cells. Science 1984;227:1477-9.
35. Bottinger EP, Bitzer M. TGF-beta signaling in renal disease. J Am Soc Nephrol 2002;13:2600-10.
36. Futrakul N, Yenrudi S, Sensirivatana R, Watana D, Laohapaibul A, Watanapenphaibul K, et al. Peritubular capillary flow determines tubulointerstitial disease in idiopathic nephrotic syndrome. Ren Fail 2000;22:329-35.
37. Fogo A. Nephrotic syndrome: molecular and genetic basis. Nephron 2000;85:8-13.
38. Futrakul P, Futrakul N, Sitprija V. Enhanced renal perfusion improves function in severe nephrosis with focal segmental glomerulosclerosis. Nephrology 1994;1:51-7.
39. Marinides GN, Grogged GC, Cohen AH, Border WA. Enalapril and low protein reverse chronic puromycin aminonucleoside nephropathy. Kidney Int 1990;37:749-57.
40. Anderson S, Rennke HG, Brenner BM. Therapeutic advantage of converting enzyme inhibitors arresting progressive renal disease associated with systemic hypertension in the rat. J Clin Invest 1986;77:1993-2000.
41. Stefanski A, Amann K, Ritz E. To prevent progression: ACE inhibitors, calcium antagonists or both? Nephrol Dial Transplant 1995;10:151-2.
42. Remuzzi A, Benigni A, Malanchini B, Bruzzi I, Foglieni C, Remuzzi G. ACE inhibition prevents renal failure and death in uninephrectomized MWF/Ztm rats. Kidney Int 1995;47:1319-26.
43. . Futrakul N, Boonyen M, Patumraj S, Siriviriyakul P, Tosukhowong P, Futrakul P. Treatment of glomerular endothelial dysfunction in steroid-resistant nephrosis with Ganoderma lucidum, vitamins C, E and vasodilators. Clin Hemorheol Microcirc 2003;29:205-10.
44. Ito S, Yasaki T. Effect of dipyridamole treatment on proteinuria in pediatric renal disease. Nephron 1980;44:174-9.
45. Woo KT, Whitworth JA, Kincaid-Smith P. Effect of antiplatelet agents on circulating platelet aggregates in patients with glomerulonephritis. Thromb Res 1980;20:663-8.
46. Taddei S, Virdis A, Ghiadoni L, Magagna A, Salvetti A. Vitamin C improves endothelium dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation 1998;97:2222-9.
47. Lee HS, Jeong JY, Kim BC, Kim YS, Zhang YZ, Chung HK. Dietary antioxidant inhibits lipoprotein oxidation and renal injury in experimental focal segmental glomerulosclerosis. Kidney Int 1997;51:1151-9.
48. Trachtman H, Schwob N, Maesaka J, Valderrama E. Dietary vitamin E supplementation ameliorates renal injury in chronic puromycin aminonucleoside nephropathy. J Am Soc Nephrol 1995;5:1811-9.
49. Futrakul N, Boongen M, Tosukhowong P, Patumraj S, Futrakul P. Treatment with vasodilators and crude extract of Ganoderma lucidum suppresses proteinuria in nephrosis with focal segmental glomerulosclerosis. Nephron 2002;92:719-20.
50. Futrakul P, Yenrudi S, Futrakul N, Sensirivatana R, Kingwatanakul P, Jungthirapanich J, et al. Tubular function and tubulointerstitial disease. Am J Kidney Dis 1999;33:886-91.
51. Futrakul N, Yenrudi S, Sensirivatana R, Cherdkiadtikul T, Laohapaibul A, Futrakul S, et al. Peritubular capillary flow and tubular function in idiopathic nephrotic syndrome. Nephron 2000;85:181-2.
52. Komine N, Khang S, Wead LM, Blantz RC, Gabbar FB. Effect of combining an ACE inhibitor and an angiotensin II receptor blocker on plasma and kidney tissue angiotensin II levels. Am J Kidney Dis 2002;39:159-64.
53. Remuzzi A, Gagliardini E, Donadino C, Fassi A, Sangalli F, Lepre MS, et al. Effect of angiotensin II antagonism on the regression of kidney disease in the rat. Kidney Int 2002;62:885-94.