Chimerism and tolerance post-in utero transplantation with embryonic stem cells

Transplantation

Volumn 78, Issue 9, 2004, Pages 1274-1282

  Moustafa, Mohamed E ^a,b   Srivastava, Anand S ^b   Nedelcu, Elena ^b   Donahue, Jody ^b   Gueorguieva, Ivelina ^b   Shenouda, Steve S ^b   Minev, Boris ^b   Carrier, Ewa ^b,c  

^a Alexandria University Faculty Of Science   (Egypt)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Embryonic stem cells; Immunity; In utero transplantation; Tolerance; Transplantation

Indexed keywords

CYTOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; EMBRYO CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MAJOR HISTOCOMPATIBILITY COMPLEX; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; TH1 CELL; TH2 CELL; TRANSPLANTATION TOLERANCE;

ANIMALS; CHIMERISM; CYTOKINES; FEMALE; FETUS; IMMUNE TOLERANCE; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; STEM CELL TRANSPLANTATION;

EID: 8644226034     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000137267.17002.B5     Document Type: Article

References (30)

1. Andreani M, Manna M, Lucarelli G, et al. Persistence of mixed chimerism in patients transplanted for the treatment of thalassemia. Blood 1996; 87: 3494.
2. Carrier E, Gilpin E, Lee TH, et al. Microchimerism does not induce tolerance after in utero transplantation and may lead to the development of alloreactivity. J Lab Clin Med 2000; 136: 224.
3. Flake AW, Roncarolo MG, Puck JM, et al. Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow. N Engl J Med 1996; 335: 1806.
4. Gil J, Porta F, Bartolome J, et al. Immune reconstitution after in utero bone marrow transplantation in a fetus with severe combined immunodeficiency with natural killer cells. Transplant Proc 1999; 31: 2581.
5. Wengler GS, Lanfranchi A, Frusca T, et al. In-utero transplantation of parental CD34 haematopoietic progenitor cells in a patient with X-linked severe combined immunodeficiency (SCIDXI). Lancet 1996; 348: 1484.
6. Westgren M, Ringden O, Bartmann P, et al. Prenatal T-cell reconstitution after in utero transplantation with fetal liver cells in a patient with X-linked severe combined immunodeficiency. Am J Obstet Gynecol 2002; 187: 475.
7. Flake AW, Zanjani ED. In utero transplantation for thalassemia. Ann N Y Acad Sci 1998; 850: 300.
8. Westgren M, Ringden O, Eik-Nes S, et al. Lack of evidence of permanent engraftment after in utero fetal stem cell transplantation in congenital hemoglobinopathies. Transplantation 1996; 61: 1176.
9. Sefrioui H, Donahue J, Srivastava AS, et al. Alloreactivity following in utero transplantation of cytokine-stimulated hematopoietic stem cells: the role of recipient CD4(-) cells. Exp Hematol 2002; 30: 617.
10. Donahue J, Gilpin E, Lee TH, et al. Microchimerism does not induce tolerance and sustains immunity after in utero transplantation. Transplantation 2001; 71: 359.
11. Donahue J, Gilpin E, Young D, et al. Postnatal cytokines and boosts improve chimerism and hematological parameters in beta-thalassemic mice transplanted in utero. Transplantation 2001; 71: 1491.
12. Carrier E, Lee TH, Busch MP, et al. Induction of tolerance in nondefective mice after in utero transplantation of major histocompatibility complex-mismatched fetal hematopoietic stem cells. Blood 1995; 86: 4681.
13. Daffos F, Forestier F, Grangeot-Keros L, et al. Prenatal diagnosis of congenital rubella. Lancet 1984; 2: 1.
14. Sharma S, Pati HP, Ahuja RK, et al. Haemopoietic cell composition of human fetal liver, spleen and thymus. Med Oncol 1997; 14: 99.
15. Nagy A, Rossant J, Nagy R, et al. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A 1993; 90: 8424.
16. Carrier E, Lee TH, Busch MP, et al. Recruitment of engrafted donor cells postnataly into the blood with cytokines after in utero transplantation in mice. Transplantation 1997; 64: 627.
17. Croft M, Swain SL. Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines. J Immunol 1995; 154: 4269.
18. Kim HB, Shaaban AF, Yang EY, et al. Microchimerism and tolerance after in utero bone marrow transplantation in mice. J Surg Res 1998; 77: 1.
19. Howson-Jan K, Matloub YH, Vallera DA, et al. In utero engraftment of fully H-2-incompatible versus congenic adult bone marrow transferred into nonanemic or anemic murine fetal recipients. Transplantation 1993; 56: 709.
20. Takeuchi T, Lowry RP, Konieczny B. Heart allografts in murine systems. The differential activation of Th2-like effector cells in peripheral tolerance. Transplantation 1992; 53: 1281.
21. Sefrioui H, Donahue J, Gilpin EA, et al. Tolerance and immunity following in utero transplantation of allogeneic fetal liver cells: the cytokine shift. Cell Transplant 2003; 12: 75.
22. Gill TJ III, Repetti CF, Metlay LA, et al. Transplacental immunization of the human fetus to tetanus by immunization of the mother. J Clin Invest 1983; 72: 987.
23. Watts AM, Stanley JR, Shearer MH, et al. Fetal immunization of baboons induces a fetal-specific antibody response. Transplantation 1992; 53:1281.
24. Kawamoto H, Ikawa T, Ohmura K, et al. T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver. Immunity 2000; 12: 441.
25. Delassus S, Darche S, Kourilsky P, et al. Ontogeny of the heavy chain immunoglobulin repertoire in fetal liver and bone marrow. J Immunol 1998; 160: 3274.
26. Owen JJ, Ritter MA. Tissue interaction in the development of thymus lymphocytes. J Exp Med 1969; 129: 431.
27. Metcalf D, Moore MS. Hematopoietic cells. In: Neuberger A, Tatum EL, eds. Frontiers in Biology. North-Holland, Amsterdam, 1971: 173.
28. Drukker M, Katz G, Urbach A, et al. Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci U S A 2002; 99: 9864.
29. Lee RS, Grusby MJ, Laufer TM, et al. CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts. Transplantation 1997; 63: 1123.
30. Paul LC, Baldwin WM III. Humoral rejection mechanisms and ABO incompatibility in renal transplantation. Transplant Proc 1987; 19: 4463.