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27944474940
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note
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3) for 1 (and 2) was found to be overlapped with two methyl signals by measurement of the signal intensity.
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15
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0007555632
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27944501292
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note
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In order to confirm compounds 1 and 2 to be natural products or artifi-cial products from peridinin (3) through the isolation process, the following experiments were conducted. A solution of peridinin (3) was kept at room temperature for 3 d in the presence of Sephadex LH-20 in MeOH or silica gel in EtOAc. The formation of 1 and 2 was not observed. Therefore, compounds 1 and 2 may be the first fully characterized natural products. A compound having the same gross structure of peridinin-5,8-furanoxide as that of 1 and 2 was described to be obtained from the dinoflagellate Procentrum lima in the preceding papers for 7th Int. Symp. on Marine Natural Products (Capri, 1992) by Gonzalez and coworkers. However, the stereochemistry as well as the spectral data for the compound were not shown in the preceding paper, and subsequent publication regarding the compound has not been found so far.
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18
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27944481932
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