Immunomagnetic selection of CD34+ peripheral blood stem cells for autografting in patients with breast cancer

British Journal of Haematology

Volumn 97, Issue 4, 1997, Pages 881-888

  Hohaus, Stefan ^a   Pförsich, Margit ^a   Murea, Simona ^a   Abdallah, Alhossain ^a   Lin, Yung Sheng ^a   Funk, Liane ^a   Voso, Maria Teresa ^a   Kaul, Sepp ^a   Schmid, Hans ^a   Wallwiener, Diethelm ^a   Haas, Rainer ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Autologous transplantation; Breast cancer; CD34+ cells; Positive selection

Indexed keywords

ADULT; AGED; ANTIBODY SPECIFICITY; ARTICLE; AUTOGRAFT; BREAST CANCER; CANCER STAGING; CANCER SURVIVAL; CELL TRANSPLANTATION; CLINICAL ARTICLE; EPITHELIUM CELL; FEMALE; HIGH RISK POPULATION; HUMAN; LEUKAPHERESIS; LYMPHOCYTE SUBPOPULATION; PRIORITY JOURNAL; STEM CELL; THROMBOCYTE COUNT;

EID: 8544274429     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.1272941.x     Document Type: Article

References (22)

1. Alcorn, M.J., Holyoake, T.L., Richmond, L., Pearson, C., Farrell, E., Kyle, B., Dunlop, D.J., Fitzsimons, E., Steward, W.P., Pragnell, I.B. & Franklin, I.M. (1996) CD34-positive cells isolated from cryopreserved peripheral-blood progenitor cells can he expanded ex vivo and used for transplantation with little or no toxicity. Journal of Clinical Oncology, 14, 1839-1847.
2. + marrow cells in patients with breast cancer or neuroblastoma. Blood, 77, 1717-1722.
3. Bezwoda, W.R., Seymour, L. & Dansey, R.D. (1995) High-dose chemotherapy with hematopoietic rescue as primary treatment for metastatic breast cancer: a randomized trial. Journal of Clinical Oncology, 13, 2483-2489.
4. Brenner, M.K., Rill, D.R., Moen, R.C., Krance, R.A., Mirro, J., Jr. Anderson, W.F. & Ihle, J.N. (1993) Gene marking to trace origin of relapse after autologous bone marrow transplantation. Lancet, 341, 85-86.
5. Brugger, W., Heimfeld, S., Berenson, R.J., Mertelsmann, R. & Kanz, L. (1995) Reconstitution of hematopoiesis after high-dose chemotherapy by autologous progenitor cells generated ex vivo. New England Journal of Medicine, 333, 283-287.
6. + cells and unseparated peripheral blood progenitor cells mediate identical hematopoietic engraftment after high-dose VP16, ifosfamide, carboplatin, and epirubicin. Blood, 84, 1421-1426.
7. Civin, C.I., Trischmann, T., Kadan, N.S., Davis, J., Noga, S., Cohen, K., Duffy, B., Groenewegen, I., Wiley, J., Law, P., Hardwick, A., Oldham, F. & Gee, A. (1996) Highly purified CD34-positive cells reconstitute hematopoiesis. Journal of Clinical Oncology, 14, 2224-2233.
8. + cells predict a rapid platelet recovery after peripheral blood stem cell transplantation. Blood, 85, 3313-3319.
9. + bone marrow progenitor cells in patients with non-Hodgkin's lymphoma. Blood, 85, 1647-1654.
10. Gribben, J.G., Neuberg, D., Freedman, A.S., Gimmi, C.D., Pesek, K.W., Barber, M., Saporito, L., Wood, S.D., Coral, F., Spector, N., Rabinowe, S.N., Grossbard, M.L., Ritz, J. & Nadler, L.M. (1993) Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation. Blood, 81, 3449-3457.
11. Haas, R., Möhle, R., Frühauf, S., Goldschmidt, H., Witt, B., Flentje, M., Wannenmacher M. & Hunstein, W. (1994) Patient characteristics associated with successful mobilizing and autografting of peripheral blood progenitor cells in malignant lymphoma. Blood, 83, 3787-3794.
12. Haas, R., Schmid, H., Hahn, U., Hohaus, S., Goldschmidt, H., Murea, S., Kaufmann, M., Wannenmacher, M., Wallwiener, D., Bastert, G. & Hunstein, W. (1997) Tandem high-dose therapy with ifosfamide, epirubicin, carboplatin and peripheral blood stem cell support is an effective adjuvant treatment for high-risk primary breast cancer. European Journal of Cancer, 33, 372- 378.
13. Hardwick, R.A., Kulcinski, D., Mansour, V., Ishizawa, L., Law, P. & Gee, A.P. (1992) Design of large-scale separation systems for positive and negative immunomagnetic selection of cells using superparamagnetic microspheres. Journal of Hematotherapy, 1, 379-386.
14. Hohaus, S., Goldschmidt, H., Ehrhardt, R. & Haas, R. (1993) Successful autografting following myeloablative conditioning therapy with blood stem cells mobilized by chemotherapy plus rhG-CSF. Experimental Hematology, 21, 508-514.
15. Lane, T.A., Law, P., Maruyama, M., Young, D., Burgess, J., Mullen, M., Mealiffe, M., Terstappen, L.W.M.M., Hardwick, A., Moubayed, M., Oldham, F., Corringham, R.E.T. & Ho, A.D. (1995) Harvesting and enrichment of hematopoietic progenitor cells mobilized into the peripheral blood of normal donors by granulocyte-macrophage colony-stimulating factor (GM-CSF) or G-CSF: potential role in allogeneic marrow transplantation. Blood, 85, 275-282.
16. + cells purified from peripheral blood of breast cancer patients primed with chemotherapy and granulocyte-macrophage colony-stimulated factor. Human Gene Therapy 5, 203-208.
17. + cells for positive selection in newly diagnosed patients with myeloma and lymphoma. British Journal of Haematology, 92, 263-268.
18. + cells from leukapheresis products in breast cancer patients: comparison of immunocytochemical tumour cell staining and reverse manuscriptase-polymerase chain reaction. Blood, 89, 337-344.
19. Murea, S., Goldschmidt, H., Hahn, U., Pförsich, M., Moos, M. & Haas, R. (1996) Successful collection and transplantation of peripheral blood stem cells in cancer patients using large-volume leukaphereses. Journal of Clinical Apheresis, 11, 185-194.
20. Peters, W., Ross, M. & Vredenburgh, J.J. (1995) High-dose chemotherapy and autologous bone marrow support as consolidation after standard-dose adjuvant therapy for high-risk primary breast cancer. Journal of Clinical Oncology 11, 1132-1143.
21. 34-positive peripheral-blood progenitors and growth factors on engraftment. Journal of Clinical Oncology 12, 28-36.
22. + cells in autologous stem cell transplantation for breast cancer. Blood, 87, 1687-1691.