Existence of an abnormal nitric oxide metabolism seen in glomeruli and inner medullary collecting duct in diabetic rat

Chinese Medical Journal

Volumn 110, Issue 7, 1997, Pages 515-519

  Lin, Shanyan ^a   Chen, Jing ^a   Sun, Jianhua ^a   Zhu, Weiyu ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ARGININE; CYCLIC GMP; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DIABETIC NEPHROPATHY; GLOMERULUS BASEMENT MEMBRANE; KIDNEY BLOOD FLOW; KIDNEY COLLECTING TUBULE; MALE; NONHUMAN; RAT;

ANIMALS; CYCLIC GMP; DIABETES MELLITUS, EXPERIMENTAL; KIDNEY GLOMERULUS; KIDNEY TUBULES, COLLECTING; MALE; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 8544250642     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Mogensen CE, Christensen CK. Predicting diabetic nephropathy in insulin-dependent patients. N Engl J Med 1984; 311:89.
2. Tolins JP, Palmer RMJ, Moncada S, et al. Role of endothelium-derived relaxing factor in regulation of renal hemodynaraic responses. Am J Physiol 1990; 258:H655.
3. Craven PA, Dekubertis FR. Protein kinase C is activated in glomeruli from streptozotocin diabetic rats: possible mediation by glucose. J Clin Invest 1989; 83:1667.
4. Markewitz BA, Michael JR, Kohan DE. Cytokine-induced expression of a nitric oxide synthase in rat renal tuble cells. J Clin Invest 1993; 91:2138.
5. Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginme. Nature 1988; 333:664.
6. Vargas HM, Cuevas JM, Igrarro LJ, et al. Comparisions of the inhibitory potencies of NG-methyl-, NG-nitro- and NG-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release. J Pharmacol Exp Ther 1991; 257:1208.
7. Komers R, Allen TJ, Cooper ME. Role of endothelium-derived nitric oxide in the pathogenesis of the renal hemodynamic changes of experimental diabetes. Diabetes 1994; 43:1190.
8. Bank N, Aynedjian HS. Role of EDRF (nitric oxide) in diabetic renal hyperfiltration. Kidney Int 1993; 43:1306.
9. Mei D, Langenstoer P, O'Rourke ST, et al. Quantitative evaluation of endothelium-derived relaxing factor released from diabetic rat aorta (Abstract). FASEB J 1992; 6:A1256.
10. Wang YX, Brooks DP, Edwards RM. Attenuated glomerular cGMP production and renal vasodilation in streptozotocin-induced diabetic rats. Am J Physiol 1993; 264:R952.