Enolase and glycolytic flux play a role in the regulation of the glucose permease gene RAG1 of Kluyveromyces lactis

Genetics

Volumn 168, Issue 2, 2004, Pages 723-731

  Lemaire, Marc ^a   Wésolowski Louvel, Micheline ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENOLASE; ENOLASE 1; ENOLASE 2; GLUCOSE; GLUCOSE PERMEASE; HEXOKINASE; PERMEASE; PHOSPHOGLYCERATE KINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVITY; FUNGAL GENE; FUNGUS GROWTH; FUNGUS MUTANT; GENE EXPRESSION; GENE IDENTIFICATION; GENE ISOLATION; GLUCONEOGENESIS; GLUCOSE PERMEASE GENE; GLUCOSE TRANSPORT SYSTEM; GLYCOLYSIS; KLUYVEROMYCES; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAG1 GENE; SACCHAROMYCES CEREVISIAE;

GENE EXPRESSION REGULATION, FUNGAL; GENES, RAG-1; GLUCONEOGENESIS; GLUCOSE; GLYCOLYSIS; HEXOKINASE; KLUYVEROMYCES; MOLECULAR SEQUENCE DATA; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE SYSTEM; PHOSPHOGLYCERATE KINASE; PHOSPHOPYRUVATE HYDRATASE;

FUNGI; KLUYVEROMYCES; KLUYVEROMYCES LACTIS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 8544244858     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.104.029876     Document Type: Article

References (45)

1. AHUATZI, D., P. HERRERO, T. DE LA CERA and F. MORENO, 2004 The glucose-regulated nuclear localization of Hexokinase 2 in Saccharomyces cerevisiae is Mig-dependent. J. Biol. Chem. 279: 14440-14446.
2. BETINA, S., P. GOFFRINI, I. FERRERO and M. WÉSOLOWSKI-LOUVEL, 2001 RAG4 gene encodes a glucose sensor in Kluyveromyces lactis. Genetics 158: 541-548.
3. BIANCHI, M. M., L. TIZZANI, M. DESTRUELLE, L. FRONTALI and M. WÉSOLOWSKI-LOUVEL, 1996 The "petite-negative" yeast Kluyveromyces lactis has a single pyruvate decarboxylase gene. Mol. Microbiol. 19: 22-36.
4. BILLARD, P., S. MENART, J. BLAISONNEAU, M. BOLOTIN-FUKUHARA, H. FUKUHARA et al., 1996 Glucose uptake in Kluyveromyces lactis: role of the HGT1 gene in glucose transport. J. Bacteriol. 178: 5860-5866.
5. BISSON, L. F., and D. G. FRAENKEL, 1983 Involvement of kinases in glucose and fructose uptake by Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 80: 1730-1734.
6. BISSON, L. F., D. M. COONS, A. L. KRUCKEBERG and D. A. LEWIS, 1993 Yeast sugar transporters. Crit. Rev. Biochem. Mol. Biol. 28: 259-308.
7. BLAISONNEAU, J., H. FUKUHARA and M. WÉSOLOWSKI-LOUVEL, 1997 The Kluyveromyces lactis equivalent of caseine kinase I is required for the transcription of the gene encoding the low-affinity glucose permease. Mol. Gen. Genet. 253: 469-477.
8. BOEKE, J. D., F. LACROUTE and G. R. FINK, 1984 A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197: 345-346.
9. CHEN, T., T. HIROKO, A. CHAUDHURI, F. INOSE, M. LORD et al., 2000 Multigenerational cortical inheritance of the Rax2 protein in orienting polarity and division in yeast. Science 290: 1975-1978.
10. CHEN, X. J., 1996 Low- and high-copy-number shuttle vectors for replication in the budding yeast Kluyveromyces lactis. Gene 172: 131-136.
11. CHEN, X. J., M. WÉSOLOWSKI-LOUVEL and H. FUKUHARA, 1992 Glucose transport in the yeast Kluyveromyces lactis. II. Transcriptional regulation of the glucose transporter gene RAG1. Mol. Gen. Genet. 33: 97-105.
12. CHEN, Y., and B. TYE, 1995 The yeast Mcm1 protein is regulated posttranscriptionally by the flux of glycolysis. Mol. Cell. Biol. 15: 4631-4639.
13. CLIFTON, D., S. B. WEINSTOCK and D. G. FRAENKEL, 1978 Glycolysis mutants in Saccharomyces cerevisiae. Genetics 88: 1-11.
14. COHEN, R., J. P. HOLLAND, T. YOKOI and M. J. HOLLAND, 1986 Identification of a regulatory region that mediates glucose-independent induction of the yeast enolase gene ENO2. Mol. Cell. Biol. 6: 2287-2297.
15. COHEN, R., T. YOKOI, J. P. HOLLAND, A. E. PEPPER and M. J. HOLLAND, 1987 Transcription of the constitutively expressed yeast enolase gene ENO1 is mediated by positive and negative cis-acting regulatory sequences. Mol. Cell. Biol. 7: 2753-2761.
16. DOHMEN, R. J., A. W. M. STRASSER, C. B. HÖNER and C. P. HOLLENBERG, 1991 An efficient transformation procedure enabling long-term storage of competent cells of various yeast genera. Yeast 7: 691-692.
17. ENTIAN, K. D., and K. L. FRÖHLICH, 1984 Saccharomyces cerevisiae mutants provide evidence of hexokinase PII as a bifunctional enzyme with catalytic and regulatory domains for triggering carbon catabolite repression. J. Bacteriol. 158: 29-35.
18. FEO, S., D. ARCURI, E. PIDDINI, R. PASSANTINO and A. GIALLONGO, 2000 ENO1 gene product binds to the c-myc promoter and acts as a transcriptional repressor: relationship with Myc promoter-binding protein (MBP-1). FEBS Lett. 473: 47-52.
19. GOFFRINI, P., A. A. ALGERI, C. DONNINI, M. WÉSOLOWSKI-LOUVEL and I. FERRERO, 1989 RAG1 and RAG2: nuclear genes involved in the dependence/independence on mitochondrial respiratory function for the growth on sugars. Yeast 5: 99-106.
20. GOFFRINI, P., M. WÉSOLOWSKI-LOUVEL and I. FERRERO, 1991 A phosphoglucose isomerase gene is involved in the Rag phenotype of the yeast Kluyveromyces lactis. Mol. Gen. Genet. 228: 401-409.
21. GONZALEZ SISO, M. I., M. A. FREIRE PICOS and M. E. CERDAN, 1996 Reoxidation of the NADPH produced by the pentose phosphate pathway is necessary for the utilization of glucose by Kluyveromyces lactis rag2 mutants. FEBS Lett. 387: 7-10.
22. HAW, R., A. D. YARRAGUDI and H. UEMURA, 2001 Isolation of GCR1, a major transcription factor of glycolytic genes in Saccharomyces cerevisiae, from Kluyveromyces lactis. Yeast 18: 729-735.
23. HOLLAND, M. J., J. P. HOLLAND, G. P. THILL and K. A. JACKSON, 1981 The primary structures of two yeast enolase genes. J. Biol. Chem. 256: 1385-1395.
24. r 48,000 is an isoprotein of enolase. Nature 315: 688-690.
25. JACOBY, J., C. P. HOLLENBERG and J. HEINISCH, 1993 Transaldolase mutants in the yeast Kluyveromyces lactis provide evidence that glucose can be metabolized through the pentose phosphate pathway. Mol. Microbiol. 10: 867-876.
26. KIMATA, K., Y. TANAKA, T. INADA and H. AIBA, 2001 Expression of the glucose transporter gene, ptsG, is regulated at the mRNA degradation step in response to glycolytic flux in Escherichia coli. EMBO J. 20: 3587-3595.
27. LEE, H., Y. GUO, M. OHTA, L. XIONG, B. STEVENSON et al., 2002 LOS2, a genetic locus required for cold-responsive gene transcription encodes a bi-functional enolase. EMBO J. 21: 2692-2702.
28. LEMAIRE, M., A. GUYON, S. BETINA and M. WÉSOLOWSKI-LOUVEL, 2002 Regulation of glycolysis by case in kinase I (Rag8p) in Kluyveromyces lactis involves a DNA-binding protein, Sck1p, a homologue of Sgc1p of Saccharomyces cerevisiae. Curr. Genet. 40: 355-364.
29. MCALISTER, L., and M. J. HOLLAND, 1982 Targeted deletion of a yeast enolase structural gene. J. Biol. Chem. 257: 7181-7188.
30. MILKOWSKI, C., S. KRAMPE, J. WEIRICH, V. HASSE, E. BOHLES et al., 2001 Feedback regulation of glucose transporter gene transcription in Kluyveromyces lactis by glucose uptake. J. Bacteriol. 183: 5223-5229.
31. NEIL, H., M. LEMAIRE and M. WÉSOLOWSKI-LOUVEL, 2004 Regulation of glycolysis in Kluyveromyces lactis: role of KlGCR1 and KlGCR2 in glucose uptake and catabolism. Curr. Genet. 45: 129-139.
32. NIEDENTHAL, R., L. NILES, U. GULDENER, S. KLEIN, M. JOHNSTON et al., 1999 Systematic analysis of S. cerevisiae chromosome VIII genes. Yeast 16: 1775-1796.
33. ÖZCAN, S., and M. JOHNSTON, 1999 Function and regulation of yeast hexose transporters. Microbiol. Mol. Biol. Rev. 63: 554-569.
34. PANCHOLI, V., 2001 Multifunctional α-enolase: its role in diseases. Cell. Mol. Life Sci. 58: 902-920.
35. PRIOR, C., P. MAMESSIER, H. FUKUHARA, X. J. CHEN and M. WÉSOLOWSKI-LOUVEL, 1993 The hexokinase gene is required for the transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis. Mol. Cell. Biol. 13: 3882-3889.
36. RANDEZ-GIL, F., P. SANZ, K. ENTIAN and J. A. PRIETO, 1998 Carbon source-dependent phosphorylation of Hexokinase PII and its role in the glucose-signaling response in yeast. Mol. Cell. Biol. 18: 2940-2948.
37. REBORA, K., C. DESMOUCELLES, F. BORNE, B. PINSON and B. DAIGNAN-FORNIER, 2001 Yeast AMP pathway genes respond to adenine through regulated synthesis of a metabolic intermediate. Mol. Cell. Biol. 23: 7901-7912.
38. SATO, T., M. C. LOPEZ, S. SUGIOKA, Y. JIGAMI, H. BAKER et al., 1999 The E-box DNA binding protein Sgc1p suppresses the gcr2 mutation, which is involved in transcriptional activation of glycolytic genes in Saccharomyces cerevisiae. FEBS Lett. 463: 307-311.
39. SIKORSKI, R. S., and P. HIETER, 1989 A system of shuttle vectors and yeast host strains design for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
40. SUBRAMANIAN, A., and D. M. MILLER, 2000 Structural analysis of α-enolase. J. Biol. Chem. 275: 5958-5965.
41. SUH, J. K., L. L. POULSEN, D. M. ZIEGLER and J. D. ROBERTUS, 1999 Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 96: 2687-2691.
42. WACH, A., 1996 PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae. Yeast 12: 259-265.
43. WÉSOLOWSKI, M., A. A. ALGERI, P. GOFFRINI and H. FUKUHARA, 1982 Killer DNA plasmids of the yeast Kluyveromyces lactis. I. Mutations affecting the killer phenotype. Curr. Genet. 150: 137-140.
44. WÉSOLOWSKI-LOUVEL, M., P. GOFFRINI, I FERRERO and H. FUKUHARA, 1992a Glucose transport in the yeast Kluyveromyces lactis. I. Properties of an inducible low-affinity glucose transporter gene. Mol. Gen. Genet. 33: 89-96.
45. - mutations involved in glucose metabolism in yeast: isolation and genetic characterization. Yeast 8: 711-719.