Chemoprevention of metachronous adenomas of the large bowel: Design and interim results of a randomized trial of calcium and fibre

European Journal of Cancer Prevention

Volumn 6, Issue 2, 1997, Pages 132-138

  Faivre, J ^a   Couillault, C ^a   Kronborg, O ^a   Rath, U ^a   Giacosa, A ^a   De Oliveira, H ^a   Obrador, T ^a   O'Morain, C ^a   Andreatta, R ^b   Buset, M ^b   Crespon, B ^b   Fenger, K ^b   Justum, A M ^b   Kerr, G ^b   Legoux, J L ^b   Marks, C ^b   Matek, W ^b   Owen, R W ^b   Paillot, B ^b   Piard, F ^b   Pienkowski, P ^b   Pignatelle, M ^b   Prada, A ^b   Pujol, J ^b   Rozen, P ^b   Richter, F ^b   Seitz, J F ^b   Sturniolo, G C ^b   Zambelli, A ^b   more..

^a UNIVERSITÉ DE BOURGOGNE   (France)

^b NONE

Author keywords

Adenoma recurrence; Calcium supplements; Chemoprevention study; Fibre supplements

Indexed keywords

ACETYLSALICYLIC ACID; CALCIUM; GLUCONOLACTATE CALCIUM; ISPAGULA; SANDOCAL;

ADULT; AGED; ARTICLE; CHEMOPROPHYLAXIS; CLINICAL TRIAL; COLON ADENOMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET; DIETARY FIBER; FEMALE; HUMAN; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL;

ADENOMA; ADULT; AGED; CALCIUM, DIETARY; COLONOSCOPY; COLORECTAL NEOPLASMS; DIETARY FIBER; DISEASE-FREE SURVIVAL; EUROPE; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RESEARCH DESIGN; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 8544236210     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Baron JA, Toesteson TD, Wargovich MJ et al (1995). Calcium supplementation and rectal mucosa proliferation: a randomized controlled trial. J Natl Cancer Inst 87: 1303-7.
2. Berrino F, Sant M, Verdecchia A et al (1995). Survival cancer patients in Europe. The EUROCARE study. IARC Scientific Publications No. 132, Lyon.
3. Boutron MC, Faivre J (1993). Diet and the adenoma-carcinoma sequence. Eur J Cancer Prev 2(Suppl 2): 95-8.
4. Bussey HJR, De Cosse JJ, Deschner EE et al (1982). Randomized trial of ascorbic acid in polyposis coli cancer. Cancer 50: 1434-9.
5. De Cosse JJ, Iler HH, Lesser ML (1989). Effect of wheat fiber and vitamin C and E on rectal polyps in patients with familial adenomatous polyposis. J Natl Cancer Inst 81: 1290-97.
6. Greenberg ER, Baron JA, Tosteson TD et al (1994). A clinical trial of antioxidant vitamins to prevent colorectal adenoma. N Engl J Med 331: 141-7.
7. Hofstad B, Vatn M, Hoff G, Larsen S, Osnes M (1992). Growth of colorectal polyps: design of a prospective, randomized, placebo-controlled intervention study in patients with colorectal polyps. Eur J Cancer Prev 1: 415-22.
8. Hofstad B, Almenningen K, Vatn M et al (1995). Effect of calcium and antioxidants on growth of colorectal polyps. Gut 37(Suppl 2): A34 (Abstract).
9. Lieubray-Bornet B, Grillet-Cousin N, Belghiti-Desprat C et al (1995). Food Composition Table for the Analysis of European Multicentric Studies. Oza, Lyon.
10. McKeown-Eyssen G, Hollowya C, Jazmaji V et al (1988). A randomized trial of vitamins C and E in the prevention of recurrence of colorectal polyps. Cancer Res 48: 4701-5.
11. McKeown-Eyssen G, Bright-See E, Bruce WR, Jazmaji V, The Toronto Polyp Prevention Group (1994). A randomized trial of a low fat high fibre diet in the recurrence of colorectal polyps. J Clin Epidemiol 47: 525-36.
12. McLennan R, Macrae F Bain C et al (1995). Randomized trial of intake of fat, fiber and beta carotene to prevent colorectal adenomas. J Natl Cancer Inst 87: 1760-6.
13. Owen RW, Thompson MH, Hill MJ (1984). Analysis of metabolic profiles of steroids in faeces of healthy subjects undergoing chenodeoxycholic acid treatment by liquid gel chromatography and gas liquid chromatography mass electrometry. Steroid Biochem 21: 593-600.
14. Parkin DM, Pisani P, Ferlay J (1993). Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 54: 594-606.
15. Potter JD, Slattery ML, Bostick RM, Gapstur SM (1993). Colon cancer: a review of the epidemiology. Epidemiol Rev 15: 499-545.
16. Rooney PS, Gifford KA, Clarke PA, Hardcastle JD, Armitage NC (1994). A double-blind, randomized controlled trial of dietary calcium supplementation in individuals with adenomas (one-year results). Dis Colon Rectum 37: 41.
17. The alpha-tocopherol, beta-carotene Cancer Prevention Study Group (1994). The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330: 1029-35.
18. Vargas PA, Alberts DS (1992). Primary prevention of colorectal cancer through dietary modification. Cancer 70: 1229-35.
19. Wilpart M, Roberfroid M (1987). Intestinal carcinogenesis and dietary fibers: the influence of cellulose or fybogel chronically given after exposure to DMH. Nutr Cancer 10: 39-51.