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Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 18, 2004, Pages 4603-4606

Synthesis of 1H-pyridin-2-one derivatives as potent and selective farnesyltransferase inhibitors

(11) Wang, Le a Lin, Nan Horng a Li, Qun a Henry, Rodger F a Zhang, Haiying a Cohen, Jerome a Gu, Wen Zhen a Marsh, Kennan C a Bauch, Joy L a Rosenberg, Saul H a Sham, Hing L a

a Cancer Research (United States)

Author keywords

1H Pyridin 2 one derivative; Farnesyltransferase; Ftase inhibitor

Indexed keywords

PROTEIN FARNESYLTRANSFERASE INHIBITOR; PYRIDINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DOG; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; X RAY CRYSTALLOGRAPHY;

ADMINISTRATION, ORAL; ALKYL AND ARYL TRANSFERASES; ANIMALS; CRYSTALLOGRAPHY, X-RAY; DOGS; FARNESYLTRANSTRANSFERASE; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

CANIS FAMILIARIS;

EID: 8544229923 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.07.004 Document Type: Article

Times cited : (16)

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