QT interval increased after single dose of lofexidine

British Medical Journal

Volumn 329, Issue 7474, 2004, Pages 1075-

  Schmittner, John ^a   Schroeder, Jennifer R ^a   Epstein, David H ^a   Preston, Kenzie L ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRITLOFEX; LOFEXIDINE; METHADONE;

ADULT; ARTICLE; CASE REPORT; DRUG DEPENDENCE; DRUG DEPENDENCE TREATMENT; ELECTROCARDIOGRAPHY; FEMALE; HUMAN; PRIORITY JOURNAL; QT PROLONGATION; SINGLE DRUG DOSE;

EID: 8544221137     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.329.7474.1075     Document Type: Article

References (4)

1. Wilkins LH, Winternitz SR, Oparil S, Smith RL, Dustan HP. Lofexidine and clonidine in moderate essential hypertension. Clin Pharmacot Ther 1981;30:752-7.
2. Bednar MM, Harrigan EP, Anziano RJ, Camm AJ, Ruskin JN. The QT interval. Prog Cardiovasc Dis 2000;43(5 suppl 1):S1-45.
3. Tsai TH, Beitman RE, Gibson JP. Larson EJ, Friehe H, Fontaine R. Acute, subacute and chronic toxicity/carcinogenicity of lofexidine. Arzneimittelforschung 1982;32:955-62.
4. Roden DM. Drug-induced prolongation of the QT interval. New Engl J Med 2004;350:1013-22.