Immunofluorescent antinuclear antibody tests

Manual of Molecular and Clinical Laboratory Immunology: 7th edition

Volumn , Issue , 2022, Pages 995-1006

  Bradwell, Arthur R ^a   Hughes, Richard G ^b   Karim, Abid R ^c  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^b Binding Site Group Ltd   (United Kingdom)

^c Catherine Cookson Bldg F   (United Kingdom)

Author keywords

Antinuclear antibody tests; Antinuclear autoantibodies (ANAs); Fluorescent conjugate; HEp 2 cell; Immunofluorescence detection; Nuclear envelope; Systemic lupus erythematosus (SLE)

Indexed keywords

EID: 85182962394     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1128/9781555815905.ch112     Document Type: Chapter

References (26)

1. Abuaf, N., G. Chyderiotis, L. Grangeot-Keros, A.-M. Rouquette, G. Servais, R.-J. van de Stadt, and R. Stokes. 1998. Étude européenne, multicentrique: comparison de la sensibilité des lames de cellules HEp-2 avec des sérums contenent des anticorps anti-SSA/Ro. Option/Bio 220:(Suppl.)7-13.
2. Beck, J. S. 1961. Variations in the morphological patterns of autoimmune nuclear fluorescence. Lancet 1:1203-1205.
3. Bradwell, A. R., R. G. Hughes, and E. L. Harden. 2003. Atlas of HEp-2 Patterns, 2nd ed. The Binding Site Ltd., Birmingham, United Kingdom.
4. Bradwell, A. R., R. P. Stokes, and G. P. Mead. 1999. Advanced Atlas of Autoantibody Patterns. The Binding Site Ltd., Birmingham, United Kingdom.
5. Conrad, K., W. Schlosler, F. Hiepe, and M. J. Fritzler. 2002. Autoantibodies in Systemic Autoimmune Disease. A Diagnostic Reference, vol. 2. Pabst Science Publishers, Berlin, Germany.
6. Coons, A. H., and M. H. Kaplan. 1950. Localization of antigen in tissue cells. II. Improvements in a method for the detection of antigen by means of fluorescent antibody. J. Exp. Med. 91:1-13.
7. Emlen, W., and L. O'Neill. 1997. Clinical significance of antinuclear antibodies: comparison of detection with immunofluorescence and enzyme-linked immunosorbent assays. Arthritis Rheum. 40:1612-1618.
8. Feltkamp, T. E. W. 1996. Antinuclear antibody determination in a routine laboratory. Ann. Rheum. Dis. 55:723-727.
9. Feng, Y., X. Ke, R. Ma, Y. Chen, G. Hu, and F. Liu. 2004. Parallel detection of autoantibodies with microarrays in rheumatoid diseases. Clin. Chem. 50:416-422.
10. Hargraves, M. M., H., Richmond, and R. Morton. 1948. Presentation of 2 bone marrow elements; "tart" cell and "L.E." cell. Proc. Mayo Clin. 23:25-28.
11. Holborow, E. J., D. M. Weir, and G. D. Johnson. 1957. A serum factor in lupus erythematosus with affinity for tissue nuclei. Br. Med. J. 2:732-734.
12. Humbel, R. L. 1994. Detection of antinuclear antibodies by immunofluorescence, p. 1-16. In W. J. Van Venrooij and R. N. Maini (ed.), Manual of Biological Markers of Disease, vol. A2. Kluwer Academic Publishers, Dordrecht, The Netherlands.
13. Jaskowski, T. D., C. M. S. Schroder, T. B. Martins, C. L. Mouritsen, C. M. Litwin, and H. R. Hill. 1996. Screening for antinuclear antibodies by enzyme immunoassay. Am. J. Clin. Pathol. 105:468-473.
14. Lee, S. L., S. R. Michael, and I. L. Vural. 1951. The L.E. (Lupus Erythematosus) cell. Am. J. Med. 10:446-451.
15. Mimori, T., M. Kanai, and Y. Ishihara. 1999. Atlas of Antinuclear Antibodies. Medical and Biological Laboratories Co., Ltd., Nagoya, Japan.
16. Odis, C. V., and I. N. Targoff. 1996. PM-Scl autoantibodies, p. 642-650. In J. B. Peter and Y. Shoenfeld. (ed.), Autoantibodies. Elsevier Science B.V, Amsterdam, The Netherlands.
17. Pollock, W., and T. Ban-Hock 1999. Routine immunofluorescence detection of Ro/SS-A autoantibody using HEp-2 cells transfected with human 60 kDa Ro/SS-A. J. Clin. Pathol. 52:684-687.
18. Smolen, J. S., B. Butcher, M. J. Fritzler, T. Gordon, J. Hardin, J. R. Kalden, R. Lahita, R. N. Maini, W. Reeves, M. Reichlin, N. Rothfield, Y. Rakasaki, W. J. van Venrooij, and E. M. Tan. 1997. Reference sera for antinuclear antibodies. II. Further definition of antibody specificities in international antinuclear antibody reference sera by immunofluorescence and Western blotting. Arthritis Rheum. 40:413-418.
19. Storch, W. B. 2000. Immunofluorescence in Clinical Immunology (English edition). Birkhäuser Verlag, Basel, Switzerland.
20. Tan, E. M. 1982. Antibodies to nuclear antigens (ANA): their immunobiology and medicine. Adv. Immunol. 33:167-240.
21. Tan, E. M., T. E. W. Feltkamp, D. Alarcon-Segovia, R. L. Dawkins, H. Homma, J. R. Kalden, P. H. Lambert, A. Lange, R. N. Maini, F. C. McDuffie, J. S. McDougal, R. Norberg, and M. Wilson. 1988. Reference reagents for antinuclear antibodies. Arthritis Rheum. 31:1331.
22. Tan, E. M., T. E. W. Feltkamp, J. S. Smolen, B. Butcher, R. Dawkins, M. J. Fritzler, T. Gordon, J. A. Hardin, J. R. Kalden, R. G. Lahita, R. N. Maini, J. S. McDougal, N. F. Rothfield, R. J. Smeenk, Y. Takasaki, A. Wiik, M. R. Wilson, and J. A. Koziol. 1997. Range of antinuclear antibodies in "healthy" individuals. Arthritis Rheum. 40: 1601-1611.
23. Tan, E. M., M. J. Fritzler, J. S. McDougal, F. C. McDuffie, R. M. Nakamura, M. Reichlin, C. B. Reimer, G. C. Sharp, P. H. Schur, M. R. Wilson, and R. J. Winchester. 1982. Reference sera for antinuclear antibodies. I. Antibodies to native DNA, Sm, nuclear RNP and SS-B/La. Arthritis Rheum. 25:1003-1005.
24. Tan, E. M., J. Smolen, J. S. McDougal, B. T. Butcher, D. Conn, R. Dawkins, M. J. Fritzler, T. Gordon, J. A. Hardin, J. R. Kalden, R. G. Lahita, R. N. Maini, N. A. Rothfield, R. Smeenk, Y. Takasaki, W. J. van Venrooij, A. Wiik, M. Wilson, and J. A. Koziol. 1999. A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities. Arthritis Rheum. 42:455-464.
25. Tan, E. M., J. Smolen, J. S. McDougal, M. J. Fritzler, T. Gordon, J. A. Hardin, J. R. Kalden, R. G. Lahita, R. N. Maini, W. H. Reeves, N. F. Rothfield, Y. Takasaki, A. Wiik, M. Wilson, and J. A. Kozoil. 2002. A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content. J. Rheum. 29:68-74.
26. Von Muhlen, C. A., and E. M. Tan. 1995. Autoantibodies in the diagnosis of systemic rheumatic diseases. Semin. Arthritis Rheum. 24:323-358.