Immunochemical characterization of immunoglobulins in serum, urine, and cerebrospinal fluid

Manual of Molecular and Clinical Laboratory Immunology: 7th edition

Volumn , Issue , 2022, Pages 88-100

  Katzmann, Jerry A ^a   Kyle, Robert A ^a  

^a Mayo Clinic   (United States)

Author keywords

Acute inflammatory polyradiculoneuropathy; Cerebrospinal fluid; Monoclonal gammopathies; Multiple sclerosis (MS); Serum; Urine

Indexed keywords

EID: 85182959100     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1128/9781555815905.ch10     Document Type: Chapter

References (35)

1. Andersson, M., J. Alvarez-Cermeno, G. Bernardi, I. Cogato, P. Fredman, P. Frederiksen, S. Fredrikson, P. Gallo, L. M. Grimaldi, M. Gronning, et al. 1994. Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report. J. Neurol. Neurosurg. Psychiatry 57:897-902.
2. Bienvenu, J., M. S. Graziani, F. Arpin, H. Bernon, C. Blessum, C. Marchetti, G. Righetti, M. Somenzini, G. Verga, and F. Aguzzi. 1998. Multicenter evaluation of the Paragon CZE 2000 capillary zone electrophoresis system for serum protein electrophoresis and monoclonal protein typing. Clin. Chem. 44:599-605.
3. Bossuyt, X., A. Bogaerts, G. Schiettekatta, and N. Blanckaert. 1998. Detection and classification of paraproteins by capillary immunofixation/subtraction. Clin. Chem. 44:760-764.
4. Cavuoti, D., L. Baskin, and I. Jialal. 1998. Detection of oligoclonal bands in cerebrospinal fluid by immunofixation electrophoresis. Am. J. Clin. Pathol. 109:585-588.
5. Cowdrey, G. N., P. G. Tasker, B. J. Gould, M. Rice-Oxley, and G. B. Firth. 1993. Isoelectric focusing in an immobilized pH gradient for the detection of intrathecal IgG in cerebrospinal fluid: sensitivity and specificity for the diagnosis of multiple sclerosis. Ann. Clin. Biochem. 30:463-468.
6. Dreicer, R., and R. Alexanian. 1982. Nonsecretory multiple myeloma. Am. J. Hematol. 13:313-318.
7. Ebers, G. C., and D. W. Paty. 1980. CSF electrophoresis in one thousand patients. Can. J. Neurol. Sci. 7:275-280.
8. Fortini, A. S., E. L. Sanders, B. G. Weinshenker, and J. A. Katzmann. 2003. Cerebrospinal fluid oligoclonal bands in the diagnosis of multiple sclerosis. Isoelectric focusing with IgG immunoblotting compared with highresolution agarose gel electrophoresis and cerebrospinal fluid IgG index. Am. J. Clin. Pathol. 120:672-675.
9. Franklin, E. C. 1975. γ- and μ-heavy chain diseases and related disorders. J. Clin. Pathol. 28 (Suppl. 6 [Assoc. Clin. Pathol.]):65-71.
10. Geraci, L., G. Merlini, A. Spadano, S. Di Matteo, G. Torlontano, and E. Ascari. 1985. Alpha heavy chain disease: report of two cases. Haematologica 70:431-436.
11. Gerson, B., S. R. Cohen, I. M. Gerson, and G. H. Guest. 1981. Myelin basic protein, oligoclonal bands, and IgG in cerebrospinal fluid as indicators of multiple sclerosis. Clin. Chem. 27:1974-1977.
12. Gutman, A. B. 1948. The plasma proteins in disease. Adv. Protein Chem. 4:155-250.
13. Henskens, Y., J. de Winter, M. Pekelharing, and G. Ponjee. 1998. Detection and identification of monoclonal gammopathies by capillary electrophoresis. Clin. Chem. 44:1184-1190.
14. Hershey, L. A., and J. L. Trotter. 1980. The use and abuse of the cerebrospinal fluid IgG profile in the adult: a practical evaluation. Ann. Neurol. 8:426-434.
15. Kabat, E. A., H. Landow, and D. H. Moore. 1942. Electrophoretic patterns of concentrated cerebrospinal fluid. Proc. Soc. Exp. Biol. Med. 49:260-263.
16. Katzmann, J. A., R. Clark, E. Sanders, J. P. Landers, and R. A. Kyle. 1998. Prospective study of serum protein capillary zone electrophoresis and immunotyping of monoclonal proteins by immunosubtraction. Am. J. Clin. Pathol. 110:503-509.
17. Keren, D. F. 2003. Protein Electrophoresis in Clinical Diagnosis. Arnold Publishing, London, United Kingdom.
18. Keren, D. F. 1998. Capillary zone electrophoresis in the evaluation of serum protein abnormalities. Am. J. Clin. Pathol. 110:248-252.
19. Keren, D. E, R. Alexanian, J. A. Goeken, P. D. Gorevic, R. A. Kyle, and R. H. Tomar. 1999. Guidelines for clinical and laboratory evaluation of patients with monoclonal gammopathies. Arch. Pathol. Lab. Med. 123:106-107.
20. Keren, D. E, J. S. Warren, and J. B. Lowe. 1998. Strategy to diagnose monoclonal gammopathies in serum: highresolution electrophoresis, immunofixation, and kappa/ lambda quantification. Clin. Chem. 34:2196-2201.
21. Kyle, R. A. 1999. Sequence of testing for monoclonal gammopathies. Arch. Pathol. Lab. Med. 123:114-118.
22. Kyle, R. A., R. C. Bieger, and G. J. Gleich. 1970. Diagnosis of syndromes associated with hyperglobulinemia. Med. Clin. N. Am. 54:917-938.
23. Kyle, R. A., and M. A. Gertz. 1995. Primary systemic amyloidosis: clinical and laboratory features in 474 cases. Semin. Haematol. 32:45-59.
24. Kyle, R. A., M. A. Gertz, T. E. Witzig, J. A. Lust, M. Q. Lacy, A. Dispenzieri, R. Fonseca, S. V. Rajkumar, J. R. Offord, D. R. Larson, M. E. Plevak, T. M. Therneau, and P. R. Greipp. 2003. Review of 1027 patients with newly diagnosed multiple myeloma. Mayo Clin. Proc. 78:21-33.
25. Kyle, R. A., R. A. Robinson, and J. A. Katzmann. 1981. The clinical aspects of biclonal gammopathies. Review of 57 cases. Am. J. Med. 71:999-1008.
26. Kyle, R. A., T. M. Therneau, S. V Rajkumar, J. R. Offord, D. R. Larson, M. E Plevak, and L. J. Melton III. 2003. Prevalence of monoclonal gammopathy of undetermined significance (MGUS) among Olmsted County, MN residents 50 years of age. Blood 102:934a (A3476).
27. Lunding, J., R. Midgard, and C. A. Vedeler. 2000. Oligoclonal bands in cerebrospinal fluid: a comparative study of isoelectric focusing, agarose gel electrophoresis, and IgG index. Acta Neurol. Scand. 102:322-325.
28. Petereit, H. E, and W. D. Heiss. 2002. New diagnostic criteria for multiple sclerosis. Ann. Neurol. 51:533-534.
29. Poser, C. M. 1985. Multiple sclerosis and other diseases of the white matter, p. 996-1006. In R. B. Conn (ed.), Current Diagnosis, 7th ed. W. B. Saunders Company, Philadelphia, Pa.
30. Rubio-Felix, D., M. Giralt, M. P. Giraldo, J. M. Martinez-Penuela, F. Oyarzabal, F. Sala, and A. Raichs. 1987. Nonsecretory multiple myeloma. Cancer 59:1847-1852.
31. Seligmann, M. 1975. Alpha-chain disease. J. Clin. Pathol. 28(Suppl. 6 [Assoc. Clin. Pathol.]):72-76.
32. Solomon, A. 1976. Bence Jones proteins and light chains of immunoglobulins. N. Engl. J. Med. 294:17-23.
33. Solomon, A. 1985. Light chains of human immunoglobulins. Methods Enzymol. 116:101-121.
34. Sun, T., S. Peng, and L. Narurkar. 1994. Modified immunoselection technique for definitive diagnosis of heavy-chain disease. Clin. Chem. 40:664.
35. Wahner-Roedler, D. L., T. E. Witzig, L. L. Loehrer, and R. A. Kyle. 2003. y-Heavy chain disease. Review of 23 cases. Medicine 82:236-250.