BACTERIAL MULTIDRUG RESISTANCE MEDIATED BY ABC TRANSPORTERS

ABC Proteins: from Bacteria to Man

Volumn , Issue , 2003, Pages 243-262

  Poelarends, Gerrit J ^a   Vigano, Catherine ^b   Ruysschaert, Jean Marie ^b   Konings, Wil N ^c  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85163538466     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012352551-2/50013-5     Document Type: Chapter

References (56)

1. G.A. Altenberg, C.G. Vanoye, J.K. Horton and L. Reuss (1994) Unidirectional fluxes of rhodamine 123 in multidrug resistant cells: evidence against direct extrusion from the plasma membrane. Proc. Natl Acad. Sci. USA 91 4654-4657.
2. E.A. Austin, J.F. Graves, L.A. Hite, C.T. Parker and C.A. Schnaitman (1990) Genetic analysis of lipopolysaccharide core biosynthesis by Escherichia coli K12: insertion mutagenesis of the rfa locus. J. Bacteriol. 172 5312-5325.
3. M.I. Barrasa, J.A. Tercero, R.A. Lacalle and A. Jimenez (1995) The ard1 gene from Streptomyces capreolus encodes a polypeptide of the ABC-transporters superfamily which confers resistance to the aminonucleoside antibiotic A201A. Eur. J. Biochem. 228 562-569.
4. B.E. Bauer, H. Wolfger and K. Kuchler (2000) Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim. Biophys. Acta 1461 217-236.
5. H. Bolhuis, D. Molenaar, G. Poelarends, H.W. van Veen, B. Poolman, A.J.M. Driessen and W.N. Konings (1994) Proton motive force-driven and ATP-dependent drug extrusion systems in multidrug-resistant Lactococcus lactis. J. Bacteriol. 176 6957-6964.
6. H. Bolhuis, G. Poelarends, H.W. van Veen, B. Poolman, A.J.M. Driessen and W.N. Konings (1995) The lactococcal lmrP gene encodes a proton motive forcedependent drug transporter. J. Biol. Chem. 270 26092-26098.
7. H. Bolhuis, H.W. van Veen, D. Molenaar, B. Poolman, A.J.M. Driessen and W.N. Konings (1996) Multidrug resistance in Lactococcus lactis: Evidence for ATP-dependent drut extrusion from the inner leaflet of the cytoplasmic membrane. EMBO J. 15 4239-4245.
8. P. Borst, N. Zelcer and A. van Helvoort (2000) ABC transporters in lipid transport. Biochim. Biophys. Acta 1486 128-144.
9. G. Chang and C.B. Roth (2001) Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters. Science 293 1793-1800.
10. M.L. Cohen (1992) Epidemiology of drug resistance: implications for a postantimicrobial era. Science 257 1050-1055.
11. B.J. Culliton (1992) Drug-resistant TB may bring epidemic. Nature 356 473.
12. U. Fringeli and H. Günthard (1981) E. Grell (Ed.) Membrane Spectroscopy Berlin, Heidelberg, New York: Springer 270-332.
13. F. Gasser (1994) Safety of lactic acid bacteria and their occurrence in human clinical infections. Bull. Inst. Pasteur 92 45-67.
14. E. Goormaghtigh, V. Cabiaux and J.M. Ruysschaert (1994) Determination of soluble and membrane protein structure by Fourier transform infrared spectroscopy. III. Secondary structures. Subcell. Biochem. 23 405-450.
15. L.M. Greenberger (1993) Major photoaffinity drug labelling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domains 6 and 12. J. Biol. Chem. 268 11417-11425.
16. V. Grimard, C. Vigano, A. Margolles, R. Wattiez, H.W. van Veen, W.N. Konings, J.-M. Ruysschaert and E. Goormaghtigh (2001) Structure and dynamics of the membrane-embedded domain of LmrA investigated by coupling polarized ATR-FTIR spectroscopy and 1H/2H exchange. Biochemistry 40 11876-11886.
17. P.G. Guilfoile and C.R. Hutchinson (1991) A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin. Proc. Natl Acad. Sci. USA 88 8553-8557.
18. J.D. Hayes and C.R. Wolf (1990) Molecular mechanisms of drug resistance. Biochem. J. 272 281-295.
19. C.F. Higgins (1992) ABC transporters: from microorganisms to man. Annu. Rev. Cell Biol. 8 67-113.
20. C.F. Higgins and M.M. Gottesman (1992) Is the multidrug transporter a flippase? Trends Biochem. Sci. 17 18-21.
21. C.F. Higgins and K.J. Linton (2001) The xyz of ABC transporters. Science 293 1782-1784.
22. L. Homolya, Z. Hollô, U.A. Germann, I. Pastan, M.M. Gottesman and B. Sarkadi (1993) Fluorescent cellular indicators are extruded by the multidrug resistance protein. J. Biol. Chem. 268 21493-21496.
23. M. Kolaczkowski, M. van der Rest, A. Cybularz-Kolaczkowski, J.-P. Soumillion, W.N. Konings and A. Goffeau (1996) Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p. J. Biol. Chem. 271 31543-31548.
24. K.J. Linton, H.N. Cooper, I.S. Hunter and P.F. Leadleay (1994) An ABC-transporter from Streptomyces longisporoflavus confers resistance to the polyether-ionophore antibiotic tetronasin. Mol. Microbiol. 11 777-785.
25. T.W. Loo and D.M. Clarke (2000) Identification of residues within the drug-binding domain of the human multidrug resistance P-glycoprotein by cysteine-scanning mutagenesis and reaction with dibromobimane. J. Biol. Chem. 275 39272-39278.
26. L. Manciu, X.B. Chang, J.R. Riordan and J.M. Ruysschaert (2000) Multidrug resistance protein MRP1 reconstituted into lipid vesicles: secondary structure and nucleotide-induced tertiary structure changes. Biochemistry 39 13026-13033.
27. A. Margolles, M. Putman, H.W. van Veen and W.N. Konings (1999) The purified and functionally reconstituted multidrug transporter LmrA of Lactococcus lactis mediates the transbilayer movement of specific fluorescent phospholipids. Biochemistry 38 16298-16306.
28. C. Martin, G. Berridge, C.F. Higgins and R. Callaghan (1997) The multidrug resistance reversal agent SRβ3557 and modulation of vinca alkaloid binding to P-glycoprotein by an allosteric interaction. Br. J. Pharmacol. 122 756-771.
29. H. Nikaido (1994) Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science 264 382-388.
30. C. Olano, A.M. Rodríguez, C. Méndez and J.A. Salas (1995) A second ABC transporter is involved in oleandomycin resistance and its secretion by Streptomyces antibioticus. Mol. Microbiol. 16 333-343.
31. Z. Podlesek, A. Comino, B. Herzog-Velikonja, D. Å¿gur-Bertok, R. Komel and M. Grabnar (1995) Bacillus licheniformis bacitracin-resistance ABC transporter: relationship to mammalian multidrug resistance. Mol. Microbiol. 16 969-976.
32. M. Putman, H.W. van Veen, J.F. Degener and W.N. Konings (2000) Antibiotic resistance: era of the multidrug pump. Mol. Microbiol. 36 772-774.
33. M. Putman, H.W. van Veen and W.N. Konings (2000) Molecular properties of bacterial multidrug transporters. Microbiol. Mol. Biol. Rev. 64 672-693.
34. M. Putman, H.W. van Veen, J.E. Degener and W.N. Konings (2001) The lactococcal secondary multidrug transporter LmrP confers resistance to lincosamides, macrolides, streptogramins and tetracyclines. Microbiology 147 2873-2880.
35. Y. Raviv, H.B. Pollard, E.P. Bruggeman, I. Pastan and M.M. Gottesman (1990) Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells. J. Biol. Chem. 265 3975-3980.
36. M.C. Roberts (1996) Tetracycline resistance determinants: mechanisms of action, regulation of expression, genetic mobility, and distribution. FEMS Microbiol. Rev. 19 1-24.
37. A.M. Rodríguez, C. Olano, C. Vilches, C. Méndez and J.A. Salas (1993) Streptomyces antibioticus contains at least three oleandomycin-resistance determinants, one of which shows similarity with proteins of the ABC-transporter superfamily. Mol. Microbiol. 8 571-582.
38. Y. Romsicki and F.J. Sharom (1999) The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter. Biochemistry 38 6887-6896.
39. M.F. Rosenberg, G. Velarde, R.C. Ford, C. Martin, G. Berridge, I.D. Kerr, et al. (2001) Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle. EMBO J. 20 5615-5625.
40. J.I. Ross, E.A. Eady, J.H. Cove, W.J. Cunliffe, S. Baumberg and J.C. Wootton (1990) Inducible erythromycin resistance in staphylococci is encoded by a member of the ATP-binding transport super-gene family. Mol. Microbiol. 4 1207-1214.
41. K. Sakamoto, A. Margolles, H.W. van Veen and W.N. Konings (2001) Hop resistance in the beer spoilage bacterium Lactobacillus brevis is mediated by the ATP-binding cassette multidrug transporter HorA. J. Bacteriol. 183 5371-5375.
42. M. Sami, H. Yamahita, T. Hirono, H. Kadokura, K. Kitamoto, K. Yoda and M. Yamasaki (1997) Hop-resistant Lactobacillus brevis contains a novel plasmid harboring a multidrug resistance-like gene. J. Ferment. Bioeng. 84 1-6.
43. M. Sami, K. Suzuki, K. Sakamoto, H. Kadokura, K. Kitamoto and K. Yoda (1998) A plasmid pRH45 of Lactobacillus brevis confers hop resistance. J. Gen. Appl. Microbiol. 44 361-363.
44. A.E. Senior, M.K. Al-Shawi and I.L. Urbatsch (1995) The catalytic cycle of P-glycoprotein. FEBS Lett. 377 285-289.
45. A.B. Shapiro and V. Ling (1997) Extraction of Hoechst 33342 from the cytoplasmic leaflet of the plasma membrane by P-glycoprotein. Eur. J. Biochem. 250 122-129.
46. A.B. Shapiro and V. Ling (1997) Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur. J. Biochem. 250 130-137.
47. F.J. Sharom, X. Yu, G. Didiodato and J.W.K. Chu (1996) Synthetic hydrophobic peptides are substrates for P-glycoprotein and stimulate drug transport. Biochem. J. 320 421-428.
48. N. Sonveaux, A.B. Shapiro, E. Goormaghtigh, V. Ling and J.M. Ruysschaert (1996) Secondary and tertiary structure changes of reconstituted P-glycoprotein. A Fourier transform attenuated total reflection infrared spectroscopy analysis. J. Biol. Chem. 271 24617-24624.
49. K. Ueda, Y. Taguchi and M. Morishima (1997) How does P-glycoprotein recognize its substrates? Semin. Cancer Biol. 8 151-159.
50. H.W. van Veen and W.N. Konings (1998) The ABC family of multidrug transporters in microorganisms. Biochim. Biophys. Acta 1365 31-36.
51. H.W. van Veen, K. Venema, H. Bolhuis, I. Oussenko, J. Kok, B. Poolman, A.J.M. Driessen and W.N. Konings (1996) Multidrug resistance mediated by a bacterial homolog of the human drug transporter MDR1. Proc. Natl Acad. Sci. USA 93 10668-10672.
52. H.W. van Veen, R. Callaghan, L. Soceneantu, a. Sardini, W.N. Konings and C.F. Higgins (1998) A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. Nature 391 291-295.
53. H.W. van Veen, M. Putman, A. Margolles, K. Sakamoto and W.N. Konings (1999) Structure-function analysis of multidrug transporters in Lactococcus lactis. Biochim. Biophys. Acta 1461 201-206.
54. H.W. van Veen, A. Margolles, M. Müller, C.F. Higgins and W.N. Konings (2000) The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J. 19 2503-2514.
55. H.W. van Veen, C.F. Higgins and W.N. Konings (2001) Multidrug transport by ATP binding cassette transporters: a proposed two-cylinder engine mechanism. Res. Microbiol. 152 365-374.
56. C. Vigano, A. Margolles, H.W. van Veen, W.N. Konings and J.M. Ruysschaert (2000) Secondary and tertiary structure changes of reconstituted LmrA induced by nucleotide binding or hydrolysis. J. Biol. Chem. 275 10962-10967.