Alphaviruses

BIODEFENSE: Research Methodology and Animal Models

Volumn , Issue , 2005, Pages 181-206

  Pratt, William D ^a   Hart, Mary Kate ^a   Reed, Douglas S ^a   Steele, Keith E ^b  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85152316908     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9781420038118-15     Document Type: Chapter

References (95)

1. Weaver, S.C. et al., Venezuelan equine encephalitis, Annu Rev Entomol. 49, 141-174, 2004.
2. Richmond, J.Y. and McKinney, R.W., Biosafety in Microbiological and Biomedical Laboratories, 4th ed., U.S. Department of Health and Human Services, Government Printing Office, Washington, DC, 1999.
3. NIAID Biodefense Research Agenda for Category B and C Priority Pathogens, U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases; NIH Publication 03-5315, 2003.
4. Smith, J.F. et al., Viral encephalitides, in Textbook of Military Medicine; Medical Aspects of Chemical and Biological Warfare, Office of the Surgeon General, Washington, DC, 1997, pp. 561-589.
5. Zhang, W. et al., Placement of the structural proteins in Sindbis virus, J Virol. 76, 11645-58, 2002.
6. Grieder, F.B. and Nguyen, H.T., Virulent and attenuated mutant Venezuelan equine encephalitis virus show marked differences in replication in infection in murine macrophages, Microb Pathog. 21, 85-95, 1996.
7. Roehrig, J.T., Day, J.W., and Kinney, R.M., Antigenic analysis of the surface glycoproteins of a Venezuelan equine encephalomyelitis virus (TC-83) using monoclonal antibodies, Virology. 118, 269-78, 1982.
8. White, J., Kielian, M., and Helenius, A., Membrane fusion proteins of enveloped animal viruses, Q Rev Biophys. 16, 151-95, 1983.
9. Paredes, A.M. et al., Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion, Virology. 324, 373-86, 2004.
10. Simons, K. and Garoff, H., The budding mechanisms of enveloped animal viruses, J Gen Virol. 50, 1-21, 1980.
11. Gliedman, J.B., Smith, J.F., and Brown, D.T., Morphogenesis of Sindbis virus in cultured Aedes albopictus cells, J Virol. 16, 913-26, 1975.
12. Weaver, S.C. et al., Family Togaviridae, in In Virus Taxonomy: Classification and Nomenclature of Viruses: Seventh Report of the International Committee on Taxonomy of Viruses, Van Regenmortel, M. H. V., Fauquet, C. M., Bishop, D. H. L., Carstens, E. B., Estes, M. K., Lemon, S. M., Maniloff, J., Mayo, M. A., McGeoch, D. J., Pringle, C. R., and Wickner, R. B. Academic Press, San Diego, 2000, pp. 878-89.
13. Brault, A.C. et al., Genetic and antigenic diversity among eastern equine encephalitis viruses from North, Central, and South America, Am J Trop Med Hyg. 61, 579-86, 1999.
14. Mullbacher, A. and Blanden, R.V., H-2-linked control of cytotoxic T-cell responsiveness to alphavirus infection. Presence of H-2Dk during differentiation and stimulation converts stem cells of low responder genotype to T cells of responder phenotype, J Exp Med. 149, 786-90, 1979.
15. Griffin, D.E. and Johnson, R.T., Role of the immune response in recovery from Sindbis virus encephalitis in mice, J Immunol. 118, 1070-5, 1977.
16. Jones, L.D. et al., Cytotoxic T-cell activity is not detectable in Venezuelan equine encephalitis virus-infected mice, Virus Res. 91, 255-9, 2003.
17. Mathews, J.H. and Roehrig, J.T., Determination of the protective epitopes on the glycoproteins of Venezuelan equine encephalomyelitis virus by passive transfer of monoclonal antibodies, J Immunol. 129, 2763-7, 1982.
18. Phillpotts, R.J., Jones, L.D., and Howard, S.C., Monoclonal antibody protects mice against infection and disease when given either before or up to 24 h after airborne challenge with virulent Venezuelan equine encephalitis virus, Vaccine. 20, 1497-504, 2002.
19. Jahrling, P.B., DePaoli, A., and Powanda, M.C., Pathogenesis of a Venezuelan encephalitis virus strain lethal for adult white rats, J Med Virol. 2, 109-16, 1978.
20. Brown, A. and Officer, J.E., An attenuated variant of eastern encephalitis virus: biological properties and protection induced in mice, Arch Virol. 47, 123-38, 1975.
21. Kissling, R.E. et al., Venezuelan equine encephalomyelitis in horses, Am J Hyg. 63, 274-287, 1956.
22. Johnston, R.E. and Peters, C.J., Alphaviruses, in Fields Virology, 3rd ed., Howley, P. M. Lippincott Raven, Philadelphia, 1996, pp. 843-98.
23. Jackson, A.C., SenGupta, S.K., and Smith, J.F., Pathogenesis of Venezuelan equine encephalitis virus infection in mice and hamsters, Vet Pathol. 28, 410-8, 1991.
24. Victor, J., Smith, D.G., and Pollack, A.D., The comparative pathology of Venezuelan equine encephalomyelitis, J Infect Dis. 98, 55-66, 1956.
25. Gleiser, C.A. et al., The comparative pathology of experimental Venezuelan equine encephalomyelitis infection in different animal hosts, J Infect Dis. 110, 1961.
26. Rivas, F. et al., Epidemic Venezuelan equine encephalitis in La Guajira, Colombia, 1995, J Infect Dis. 175, 828-32, 1997.
27. Weaver, S.C. et al., Re-emergence of epidemic Venezuelan equine encephalomyelitis in South America. VEE Study Group, Lancet. 348, 436-40, 1996.
28. Watts, D.M. et al., Venezuelan equine encephalitis febrile cases among humans in the Peruvian Amazon River region, Am J Trop Med Hyg. 58, 35-40, 1998.
29. Bowen, G.S. et al., Clinical aspects of human Venezuelan equine encephalitis in Texas, Bull Pan Am Health Organ. 10, 46-57, 1976.
30. de la Monte, S. et al., The systemic pathology of Venezuelan equine encephalitis virus infection in humans, Am J Trop Med Hyg. 34, 194-202, 1985.
31. Hart, M.K. et al., Venezuelan equine encephalitis virus vaccines induce mucosal IgA responses and protection from airborne infection in BALB/c, but not C3H/HeN mice, Vaccine. 15, 363-9, 1997.
32. Ludwig, G.V. et al., Comparative neurovirulence of attenuated and non-attenuated strains of Venezuelan equine encephalitis virus in mice, Am J Trop Med Hyg. 64, 49-55, 2001.
33. Phillpotts, R.J. and Wright, A.J., TC-83 vaccine protects against airborne or subcutaneous challenge with heterologous mouse-virulent strains of Venezuelan equine encephalitis virus, Vaccine. 17, 982-8, 1999.
34. Stephenson, E.H. et al., Nose-only versus whole-body aerosol exposure for induction of upper respiratory infections of laboratory mice, Am Ind Hyg Assoc J. 49, 128-35, 1988.
35. Schmaljohn, A.L. et al., Non-neutralizing monoclonal antibodies can prevent lethal alphavirus encephalitis, Nature. 297, 70-2, 1982.
36. Hart, M.K. et al., Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate, Vaccine. 18, 3067-75, 2000.
37. Steele, K.E. et al., Comparative neurovirulence and tissue tropism of wild-type and attenuated strains of Venezuelan equine encephalitis virus administered by aerosol in C3H/HeN and BALB/c mice, Vet Pathol. 35, 386-97, 1998.
38. MacDonald, G.H. and Johnston, R.E., Role of dendritic cell targeting in Venezuelan equine encephalitis virus pathogenesis, J Virol. 74, 914-922, 2000.
39. Davis, N.L. et al., A molecular genetic approach to the study of Venezuelan equine encephalitis virus pathogenesis, Arch Virol Suppl. 9, 99-109, 1994.
40. Grieder, F.B. et al., Specific restrictions in the progression of Venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins, Virology. 206, 994-1006, 1995.
41. Vogel, P. et al., Venezuelan equine encephalitis in BALB/c mice: kinetic analysis of central nervous system infection following aerosol or subcutaneous inoculation, Arch Pathol Lab Med. 120, 164-72, 1996.
42. Charles, P.C. et al., Mechanism of neuroinvasion of Venezuelan equine encephalitis virus in the mouse, Virology. 208, 662-71, 1995.
43. Ryzhikov, A.B. et al., Spread of Venezuelan equine encephalitis virus in mice olfactory tract, Arch Virol. 140, 2243-54, 1995.
44. Ryzhikov, A.B. et al., Venezuelan equine encephalitis virus propagation in the olfactory tract of normal and immunized mice, Biomed Sci. 2, 607-14, 1991.
45. Morrison, E.E. and Costanzo, R.M., Morphology of the human olfactory epithelium, J Comp Neurol. 297, 1-13, 1990.
46. Schoneboom, B.A. et al., Inflammation is a component of neurodegeneration in response to Venezuelan equine encephalitis virus infection in mice, J Neuroimmunol. 109, 132-146, 2000.
47. Griffen, D.E., The Gordon Wilson Lecture: unique interactions between viruses, neurons and the immune system, Trans Am Clin Climatol Assoc. 107, 89-98, 1995.
48. Griffen, D.E. et al., Age-dependent susceptibility to fatal encephalitis: alphavirus infection of neurons, Arch Virol Suppl. 9, 31-39, 1994.
49. Lewis, J. et al., Alphavirus-induced apoptosis in mouse brains correlates with neurovirulence, J Virol. 70, 1828-1835, 1996.
50. Ubol, S. et al., Neurovirulent strains of Alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein, Proc Natl Acad Sci USA. 91, 5202-5206, 1994.
51. Jackson, A.C. and Rossiter, J.P., Apoptotic cell death is an important cause of neuronal injury in experimental Venezuelan equine encephalitis virus infection of mice, Acta Neuropathol (Berl). 93, 349-53, 1997.
52. Woodman, D.R., McManus, A.T., and Eddy, G.A., Extension of the mean time to death of mice with a lethal infection of Venezuelan equine encephalomyelitis virus by antithymocyte serum treatment, Infect Immun. 12, 1006-11, 1975.
53. Schoneboom, B.A. et al., Astrocytes as targets for Venezuelan equine encephalitis virus infection, J Neurovirol. 5, 342-54, 1999.
54. Walker, D.H. et al., Lymphoreticular and myeloid pathogenesis of Venezuelan equine encephalitis in hamsters, Am J Pathol. 84, 351-70, 1976.
55. Austin, F.J. and Scherer, W.F., Studies of viral virulence. I. Growth and histopathology of virulent and attenuated strains of Venezuelan encephalitis virus in hamsters, Am J Pathol. 62, 195-210, 1971.
56. Jahrling, P.B. and Scherer, F., Histopathology and distribution of viral antigens in hamsters infected with virulent and benign Venezuelan encephalitis viruses, Am J Pathol. 72, 25-38, 1973.
57. Dill, G.S., Jr., Pederson, C.E., Jr., and Stookey, J.L., A comparison of the tissue lesions produced in adult hamsters by two strains of avirulent Venezuelan equine encephalomyelitis virus, Am J Pathol. 72, 13-24, 1973.
58. Gorelkin, L. and Jahrling, P.B., Virus-initiated septic shock. Acute death of Venezuelan encephalitis virus-infected hamsters, Lab Invest. 32, 78-85, 1975.
59. Pratt, W.D. et al., Genetically engineered, live attenuated vaccines for Venezuelan equine encephalitis: testing in animal models, Vaccine. 21, 3854-62, 2003.
60. Kundin, W.D., Liu, C., and Rodina, P., Pathogenesis of Venezuelan equine encephalomyelitis virus. I. Infection in suckling mice, J Immunol. 96, 39-48, 1966.
61. Hruskova, J. et al., Subcutaneous and inhalation infection of guinea pigs with Venezuelan equine encephalomyelitis virus, Acta Virol. 13, 415-21, 1969.
62. Gorelkin, L. and Jahrling, P.B., Pancreatic involvement by Venezuelan equine encephalomyelitis virus in the hamster, Am J Pathol. 75, 349-62, 1974.
63. Gleiser, C.A. et al., The comparative pathology of experimental Venezuelan equine encephalomyelitis infection in different animal hosts, J Infect Dis. 110, 80-97, 1962.
64. Monath, T.P. et al., Experimental studies of rhesus monkeys infected with epizootic and enzootic subtypes of Venezuelan equine encephalitis virus, J Infect Dis. 129, 194-200, 1974.
65. Monath, T.P. et al., Recombinant vaccinia - Venezuelan equine encephalomyelitis (VEE) vaccine protects nonhuman primates against parenteral and intranasal challenge with virulent VEE virus, Vaccine Research. 1, 55-68, 1992.
66. Reed, D.S. et al., Aerosol infection of cynomolgus macaques with enzootic strains of Venezuelan equine encephalitis viruses, J Infect Dis. 189, 1013-7, 2004.
67. Pratt, W.D. et al., Use of telemetry to assess vaccine-induced protection against parenteral and aerosol infections of Venezuelan equine encephalitis virus in nonhuman primates, Vaccine. 16, 1056-64, 1998.
68. Reed, D.S. et al., Genetically engineered, live attenuated vaccines protect nonhuman primates against aerosol challenge with a virulent IE strain of Venezuelan equine encephalitis virus, Vaccine. In press, 2005.
69. Verlinde, J.D., Susceptibility of cynomolgus monkeys to experimental infection with arboviruses of group A (Mayaro and Mucambo), group C (Oriboca and Restan) and an unidentified arbovirus (Kwatta) originating from Surinam, Trop Geogr Med. 20, 385-90, 1968.
70. Danes, L. et al., The role of the olfactory route on infection of the respiratory tract with Venezuelan equine encephalomyelitis virus in normal and operated Macaca rhesus monkeys. I. Results of virological examination, Acta Virol. 17, 50-6, 1973.
71. Danes, L. et al., Penetration of Venezuelan equine encephalomyelitis virus into the brain of guinea pigs and rabbits after intranasal infection, Acta Virol. 17, 138-46, 1973.
72. Steele, K.E. et al., Comparative neurovirulence and tissue tropism of wild-type and attenuated strains of Venezuelan equine encephalitis virus administered by aerosol in C3H/HeN and BALB/c mice, Vet Pathol. 35, 386-97, 1998.
73. Davis, N.L. et al., Attenuated mutants of Venezuelan equine encephalitis virus containing lethal mutations in the PE2 cleavage signal combined with a second-site suppressor mutation in E1, Virology. 212, 102-10, 1995.
74. Hart, M.K. et al., Onset and duration of protective immunity to IA/IB and IE strains of Venezuelan equine encephalitis virus in vaccinated mice, Vaccine. 20, 616-22., 2001.
75. Deresiewicz, R.L. et al., Clinical and neuroradiographic manifestations of eastern equine encephalitis, N Engl J Med. 337, 1393-94, 1997.
76. Farber, S. et al., Encephalitis in infants and children caused by the virus of the eastern variety of equine encephalitis, J Am Med Assoc. 114, 1725-31, 1940.
77. Bastian, F.O. et al., Eastern equine encephalitis: histopathologic and ultrastructural changes with isolation of virus in a human case, Am J Clin Pathol. 64, 10-13, 1975.
78. Murphy, F.A. and Whitfield, S.G., Eastern equine encephalitis viru infection: electron microscopic studies of mouse central nervous system., Exp Mol Pathol. 13, 131-146, 1970.
79. Liu, C. et al., A comparative study of the pathogenesis of western equine and eastern equine encephalomyelitis viral infections in mice by intracerebral and subcutaneous inoculations, J Infect Dis. 122, 53-63, 1970.
80. Morgan, I., Influence of age on susceptibility and on immune response of mice to eastern equine encephalomyelitis virus, J Exp Med. 74, 115-132, 1941.
81. Olitsky, P.K. and Harford, C.G., Intraperitoneal and intracerebral routes in serum protection tests with the virus of equine encephalomyelitis. I. A comparison of the two routes in protection tests, J Exp Med. 68, 173-189, 1938.
82. Sabin, A.B. and Olitsky, P.K., Variations in pathways by which equine encephalomyelitic viruses invade the CNS of mice and guinea pigs, Pro Soc Exp Biol Med. 38, 595-597, 1938.
83. Vogel, P. et al., Early events in the pathogenesis of eastern equine encephalitis virus in mice, Am J Pathol. 166, 159-171, 2005.
84. Sidwell, R.W. and Smee, D.F., Viruses of the Bunya-and Togaviridae families: potential as bioterrorism agents and means of control, Antiviral Res. 57, 101-111, 2003.
85. Dremov, D.P. et al., Attenuated variants of eastern equine encephalomyelitis virus: pathomorphological, immunofluorescence and virological studies of infection in Syrian hamsters, Acta Virol. 22, 139-145, 1978.
86. Paessler, S. et al., The hamster as an animal model for eastern equine encephalitis - and its use in studies of virus entrance into the brain, J Infect Dis. 189, 2072-2076, 2004.
87. Sabin, A.B. and Olitsky, P.K., Age of host and capacity of equine encephalomyelitic viruses to invade the CNS, Pro Soc Exp Biol Med. 38, 597-599, 1938.
88. Hurst, E.W., The histology of equine encephalomyelitis, J Exp Med. 59, 529-543, 1934.
89. Hurst, E.W., Infection of the rhesus monkey (Macaca mulatta) and the guinea-pig with the virus of equine encephalomyelitis, J Path Bact. 42, 271-302, 1936.
90. Wyckoff, R.W.G. and Tesar, W.C., Equine encephalomyelitis in monkeys, J Immunol. 37, 329-343, 1939.
91. Reed, D.S. et al., Aerosol exposure to western equine encephalitis virus causes fever and encephalitis in cynomolgus macaques., J Infect Dis. In press. 2005.
92. Howitt, B.F., Equine encephalomyelitis, J Infect Dis. 51, 493-510, 1932.
93. Lennette, E.H. and Koprowski, H., Influence of age on the susceptibility of mice to infection with certain neurotropic viruses, 175-191, 1943.
94. Cole, F.E., Jr. and McKinney, R.W., Use of hamsters of potency assay of eastern and western equine encephalitis vaccines, Appl Microbiol. 17, 927-8, 1969.
95. Cole, F.E., Jr. and McKinney, R.W., Cross-protection in hamsters immunized with group A arbovirus vaccines, Infect Immun. 4, 37-43, 1971.