Formulation and evaluation of matrix microspheres for simultaneous delivery of salbutamol sulphate and theophylline

Tropical Journal of Pharmaceutical Research

Volumn 7, Issue 2, 2008, Pages 995-1002

  Pachuau, L ^a   Sarkar, S ^a   Mazumder, B ^a  

^a DIBRUGARH UNIVERSITY   (India)

Author keywords

Emulsion solvent evaporation technique; Ethylcellulose; Matrix microspheres; Salbutamol sulphate; Theophylline

Indexed keywords

EID: 85097000217     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v7i2.14684     Document Type: Article

References (16)

1. Mingna Song, Ning Li, Shuying Sun, Lourens R. Tiedt, Wilna Liebenberg, Melgardt M de Villiers. Effect of viscosity and concentration of wall former, emulsifier and pore-inducer on the properties of Amoxicillin Microcapsules prepared by Emulsion Solvent Evaporation. IL Farmaco 2005; 60: 261-267
2. Amperiadou A, Georgarakis M. Controlled release salbutamol sulphate microcapsules prepared by emulsion solvent-evaporation technique and study on the release affected parameters. International Journal of Pharmaceutics 1995; 115:1-8
3. Rowland M, Tozer TN. Clinical Pharmacokinetics: Concepts and Applications, ed 3(First Indian Edition) 1996, Lea & Febiger, Philadelphia, pp 1.
4. Nishimura K, Koyama H, Ikeda A, Sugiura N, Kawakatsu K, Izumi T. The additive effect of theophylline on a high- dose combination of inhaled Salbutamol and Ipratropium bromide in stable COPD - chronic obstructive pulmonary disease. Chest 1995; 107: 718-723.
5. Murthy SN, Hiremath SR. Formulation and Evaluation of Controlled-Release Transdermal Patches of Theophylline-Salbutamol Sulfate. Drug Dev Ind Pharm 2001; 27: 1057-1062.
6. Dandagi PM, Mastiholimath VS, Patil MB, Manvi FV, Gadad AP, Ruchi Sharma. Development and Evaluation of Theophylline and Salbutamol sulphate Sustained Release Matrix Tablets. Indian Journal of Pharmaceutical Sciences 2005; 67(5): 598-602.
7. Prabakaran D, Paramjit Singh, Parijat Kanaujia, Jaganathan KS, Amit Rawat, Suresh P Vyas. Modified push-pull osmotic system for simultaneous delivery of theophylline and Salbutamol: development and in vitro characterization. International Journal of Pharmaceutics 2004; 284: 95-108.
8. Sweetman SC. ed. Martindale: The Complete Drug Reference. ed 33, Pharmaceutical Press, London, 2002, pp 757 - 786.
9. Li SP, Kowarski CR, Feld KM, Grim WM. Recent Advances in Microencapsulation Technology and Equipment. Drug Dev Ind Pharm 1988; 14: 353-376.
10. Singhvi I, Chaturvedi SC. Three Spectrophotometric methods for simultaneous estimation of Salbutamol and theophylline from tablets. Indian Drugs 1998; 35: 421-42 6.
11. Soppimath KS, Aminabhavi TM. Ethylacetate as a dispersing solvent in the production of poly(DLlactide co-glycolide) microspheres: effect of process parameters and polymer type. Journal of Microencapsulation 2002; 19: 281-292.
12. Nokhodchi A, Farid D. Microencapsulation of Paracetamol by various Emulsion Techniques using Cellulose Acetate Phthalate. Pharm Tech 2002; June: 54-60.
13. Siepmann J, Peppas NA. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv Drug Del Rev 2001; 48: 139-157.
14. Costa P, Lobo JMS. Modelling and comparison of dissolution profiles. Eur J Pharm Sci 2001; 13: 123-133.
15. Parvinder Singh, Desai SJ, Simonelli AP, William I Higuchi. Release Rates of Solid Drug Mixtures Dispersed in Inert Matrices I: Non-interacting Drug Mixtures. J Pharm Sci 1967; 56: 1542-1547.
16. Kim CK, Kim MJ, Oh KH. Preparation and evaluation of sustained release microspheres of terbutaline sulphate. International Journal of Pharmaceutics 1994; 106: 213-219.