The landscape of cardiovascular clinical trials in the united states initiated before and during covid-19

Journal of the American Heart Association

Volumn 9, Issue 18, 2020, Pages

  Selvaraj, Senthil ^a   Greene, Stephen J ^b   Khatana, Sameed Ahmed M ^a   Nathan, Ashwin S ^a   Solomon, Scott D ^c   Bhatt, Deepak L ^d  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Biomarker; Clinical trial; COVID 19; Renin angiotensin system; Troponin

Indexed keywords

CARDIOVASCULAR DISEASE; CLINICAL PRACTICE; CLINICAL TRIAL (TOPIC); CORONAVIRUS DISEASE 2019; HEART ELECTROPHYSIOLOGY; HEART FAILURE; HUMAN; INTERVENTIONAL CARDIOVASCULAR PROCEDURE; LETTER; MEDICAL RESEARCH; OUTCOME ASSESSMENT; PATIENT SELECTION; PRACTICE GUIDELINE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; UNITED STATES; BETACORONAVIRUS; COMPARATIVE STUDY; CORONAVIRUS INFECTION; HOST PATHOGEN INTERACTION; METHODOLOGY; PANDEMIC; PATHOGENICITY; PROCEDURES; TIME FACTOR; VIROLOGY; VIRUS PNEUMONIA;

BETACORONAVIRUS; CARDIOVASCULAR DISEASES; CLINICAL TRIALS AS TOPIC; CORONAVIRUS INFECTIONS; HOST-PATHOGEN INTERACTIONS; HUMANS; PANDEMICS; PNEUMONIA, VIRAL; RESEARCH DESIGN; TIME FACTORS; UNITED STATES;

EID: 85090065925     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.120.018274     Document Type: Letter

References (5)

1. Bagiella E, Bhatt DL, Gaudino M. The consequences of the COVID-19 pandemic on non-COVID-19 clinical trials. J Am Coll Cardiol. 2020;76:342–345.
2. Garcia S, Albaghdadi MS, Meraj PM, Schmidt C, Garberich R, Jaffer FA, Dixon S, Rade JJ, Tannenbaum M, Chambers J, et al. Reduction in st-segment elevation cardiac catheterization laboratory activations in the United States during COVID-19 pandemic. J Am Coll Cardiol. 2020;75:2871–2872.
3. Madjid M, Safavi-Naeini P, Solomon SD, Vardeny O. Potential effects of coronaviruses on the cardiovascular system: a review. JAMA Cardiol. 2020;5:831. [epub ahead of print].
4. Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin-angiotensin-aldosterone system inhibitors in patients with covid-19. N Engl J Med. 2020;382:1653–1659.
5. The New York Times. Coronavirus in the U.S.: latest map and case count. Available at: https://www.nytimes.com/interactive/2020/us/coron avirus-us-cases.html?action=click&pgtype=Article&state=default&-module=styln-coronavirus&variant=show®ion=TOP_BANNER&conte xt=storylines_menu#states. Accessed May 13, 2020.