Is a "cytokine Storm" Relevant to COVID-19?

JAMA Internal Medicine

Volumn 180, Issue 9, 2020, Pages 1152-1154

  Sinha, Pratik ^a   Matthay, Michael A ^a   Calfee, Carolyn S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; DEXAMETHASONE; INTERFERON; INTERLEUKIN 6; INTERLEUKIN DERIVATIVE; TOCILIZUMAB; TUMOR NECROSIS FACTOR; IMMUNOLOGIC FACTOR;

ADULT RESPIRATORY DISTRESS SYNDROME; CORONAVIRUS DISEASE 2019; CYTOKINE RELEASE; CYTOKINE RELEASE SYNDROME; CYTOKINE STORM; DISEASE SEVERITY; HUMAN; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; PRIORITY JOURNAL; REVIEW; SURVIVAL; BETACORONAVIRUS; COMPLICATION; CORONAVIRUS INFECTION; DRUG EFFECT; IMMUNOLOGY; NOMENCLATURE; PANDEMIC; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; VIRUS PNEUMONIA;

BETACORONAVIRUS; CORONAVIRUS INFECTIONS; CYTOKINE RELEASE SYNDROME; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC FACTORS; INTERLEUKIN-6; PANDEMICS; PNEUMONIA, VIRAL; TERMINOLOGY AS TOPIC;

EID: 85089579926     PISSN: 21686106     EISSN: 21686114     Source Type: Journal    
DOI: 10.1001/jamainternmed.2020.3313     Document Type: Review

References (11)

1. Wu C, Chen X, Cai Y, Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med. Published online March 13, 2020. doi: 10.1001/jamainternmed.2020.0994 32167524
2. Qin C, Zhou L, Hu Z, Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis. Published online March 12, 2020;
3. Huang KJ, Su IJ, Theron M, An interferon-gamma-related cytokine storm in SARS patients. J Med Virol. 2005; 75 (2): 185-194. doi: 10.1002/jmv.20255 15602737
4. Zhou F, Yu T, Du R, Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395 (10229): 1054-1062. doi: 10.1016/S0140-6736(20)30566-3 32171076
5. Mo P, Xing Y, Xiao Y, Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China. Clin Infect Dis. Published online March 16, 2020;
6. Cummings MJ, Baldwin MR, Abrams D, Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. Lancet. 2020; 395 (10239): 1763-1770. doi: 10.1016/S0140-6736(20)31189-2 32442528
7. Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA; NHLBI ARDS Network. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med. 2014; 2 (8): 611-620. doi: 10.1016/S2213-2600(14)70097-9 24853585
8. Famous KR, Delucchi K, Ware LB,; ARDS Network. Acute respiratory distress syndrome subphenotypes respond differently to randomized fluid management strategy. Am J Respir Crit Care Med. 2017; 195 (3): 331-338. doi: 10.1164/rccm.201603-0645OC 27513822
9. Sinha P, Delucchi KL, Thompson BT, McAuley DF, Matthay MA, Calfee CS; NHLBI ARDS Network. Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study. Intensive Care Med. 2018; 44 (11): 1859-1869. doi: 10.1007/s00134-018-5378-3 30291376
10. Ackermann M, Verleden SE, Kuehnel M, Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. N Engl J Med. Published online May 21, 2020. doi: 10.1056/NEJMoa2015432 32437596
11. Maude S, Barrett DM. Current status of chimeric antigen receptor therapy for haematological malignancies. Br J Haematol. 2016; 172 (1): 11-22. doi: 10.1111/bjh.13792 26560054