Aerodynamic performance of an earlier Venturi powdered drug and vaccines delivery system

35th AIAA Fluid Dynamics Conference and Exhibit

Volumn , Issue , 2005, Pages

  Liu, Y ^a   Costigan, G ^a   Bellhouse, B J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CONTROLLED DRUG DELIVERY; DRUG DOSAGE; SUPERSONIC AERODYNAMICS; TARGETED DRUG DELIVERY; VACCINES;

AERO-DYNAMIC PERFORMANCE; APPROPRIATE VELOCITIES; DELIVERY SYSTEMS; GAS-PARTICLE INTERACTION; INJECTION SYSTEMS; PHARMACOLOGICAL EFFECTS; SUPERSONIC JET FLOW; UNDERLYING PRINCIPLES;

COMPUTATIONAL FLUID DYNAMICS;

EID: 85088343513     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.2514/6.2005-5005     Document Type: Conference Paper

References (12)

1. Bellhouse, B.J., Sarphie, D.F. and Greenford, J.C., "Needless Syringe Using Supersonic Gas Flow for Particle Delivery, " Int. Patent WO94/24263, 1994.
2. Kendall, M.A.F., "The Delivery of Particulate Vaccines and Drugs to Human Skin with a Practical, Hand-held Shock Tube-based System, " Shock Waves Journal, 2002, 12(1), pp.22-30.
3. Costigan, G., Liu, Y., Brown, G.L., Carter, F.V. and Bellhouse, B.J., "Evolution of the Design of the Venturi Devices for the Delivery of Dry Particles to Skin or Mucosal Tissue, " Paper-2981, Proc. of 24th Int. Symp. on Shock Waves, Beijing, PR China, 2004.
4. Liu, Y., Kendall, M.A.F., Costigan, G. and Bellhouse B.J., "Prediction of Jet Flows from the Axisymmetric Supersonic Nozzle, " Paper-1511, Proc. of 24th Int. Symp. on Shock Waves, Beijing, PR China, 2004.
5. Liu, Y., Kendall, M.A.F., Truong, N.K. and Bellhouse, B.J., "Numerical and Experimental Analysis of a High Speed Needle-free Powdered Vaccines Delivery Device, " AIAA-2002-2807, Proc. of 20th AIAA Applied Aerodynamics Conference, St. Louis, USA, 2002.
6. Liu, Y. and Kendall, M.A.F., "Numerical Simulation of Heat Transfer from a Transonic Jet Impinging on Skin for Needlefree Powdered Drug and Vaccine Delivery, " Journal of Mechanical Engineering Science, Proceedings of the Institution of Mechanical Engineers Part C, 2004, 218(11), pp.1373-1383.
7. Liu, Y. and Kendall, M.A.F., "Numerical study of a Transient Gas and Particle Flow in a High-speed Needle-free Ballistic Particulate Vaccine Delivery System, " Journal of Mechanics in Medicine and Biology, 2004, 4(4), pp.559-578.
8. Smith, C.E., "The Starting Process in a Hypersonic Nozzle, " Joural of Fluid Mechanics, 1966, 24(4), pp.625-641.
9. Henderson, C.B., "Drag Coeffcient of Spheres in Continuum and Rarefied Flows, " AIAA Journal, 1976, 14(6), pp.707-708.
10. Kurian, J. and Das, H.K., "Studies of Shock Wave Propagation in Gas-particle Mixtures, " Proc. of 21st Int. Symp. on Shock Waves, Great Keppel Island, Australia, 1997.
11. Igra, O. and Takayama, K., "Shock Tube Study of the Drag Coeffcient of a Sphere in a Non-stationary Flow, " Proc R. Soc. Land. A, 1993, 442(), pp.231-2467.
12. Fluent user's guide volume, Fluent Inc. http://www.fluent.com/.