Modulation of cochlear mechanics: Model predictions and experimental findings of the effect of changing perilymph osmolarity

Auditory Mechanisms: Processes and Models - Proceedings of the 9th International Symposium

Volumn , Issue , 2005, Pages 41-48

  Oghalai, J S ^a   Choi, C H ^a   Spector, A A ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACOUSTIC EMISSIONS; AUDITION; MAMMALS; OTOACOUSTIC EMISSIONS;

BIOPHYSICAL PROPERTIES; COCHLEAR FUNCTION; COMPOUND ACTION POTENTIALS; CYLINDRICAL SHAPES; DISTORTION PRODUCT OTOACOUSTIC EMISSIONS; ELECTROMOTILITY; EXTRACELLULAR FLUID; MODEL PREDICTION;

MECHANICS;

EID: 85087093986     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (16)

1. Hallworth, R., 1995. Passive compliance and active force generation in the Guinea pig outer hair cell. J. Neurophysiol. 74, 2319-28.
2. Hallworth, R., 1997. Modulation of outer hair cell compliance and force by agents that affect hearing. Hear. Res. 114, 204-12.
3. Crist, J.R., Fallon, M., Bobbin, R.P., 1993. Volume regulation in cochlear outer hair cells. Hear. Res. 69, 194-8.
4. Oghalai, J.S., Zhao, H.B., Kutz, J.W., Brownell, W.E., 2000. Voltage- and tension-dependent lipid mobility in the outer hair cell plasma membrane. Science 287, 658-61.
5. Oghalai, J.S., 2004. Chlorpromazine inhibits cochlear function in Guinea pigs. Hear. Res. 198, 59-68.
6. Choi, C.-H., Spector, A.A., Oghalai, J.S., 2005. Perilymph Osmolarity Modulates Cochlear Function, Abstracts of the Midwinter Research Meeting of the Association for Research in Otolaryngology, New Orleans, LA.
7. Holley, M.C., Ashmore, J.F., 1988. A cytoskeletal spring in cochlear outer hair cells. Nature 335, 635-637.
8. Iwasa, K.H., Adachi, M., 1997. Force generation in the outer hair cell of the cochlea, Biophys. J., Vol. 73. pp. 546-555.
9. Kossl, M., Russell, I.J., 1995. Basilar membrane resonance in the cochlea of the mustached bat. Proc. Natl. Acad. Sci. U. S. A. 92, 276-9.
10. Ratnanather, J.T., Zhi, M., Brownell, W.E., Popel, A.S., 1996. The ratio of elastic moduli of cochlear outer hair cells derived from osmotic experiments. J. Acoust. Soc. Am. 99, 1025-8.
11. Sit, P.S., Spector, A.A., Lue, A.J., Popel, A.S., Brownell, W.E., 1997. Micropipette aspiration on the outer hair cell lateral wall. Biophys. J. 72, 2812-9.
12. Spector, A.A., 1999. Nonlinear electroelastic model for the composite outer hair cell wall. ORL. J. Otorhinolaryngol. Relat. Spec. 61, 287-93.
13. Denk, W., Webb, W.W., Hudspeth, A.J., 1989. Mechanical properties of sensory hair bundles are reflected in their Brownian motion measured with a laser differential interferometer. Proc. Natl. Acad. Sci. U. S. A. 86, 5371-5.
14. Gale, J.E., Ashmore, J.F., 1997. An intrinsic frequency limit to the cochlear amplifier. Nature 389, 63-6.
15. Hirono, M., Denis, C.S., Richardson, G.P., Gillespie, P.G., 2004. Hair cells require phosphatidylinositol 4,5-bisphosphate for mechanical transduction and adaptation. Neuron 44, 309-20.
16. Sukharev, S., Corey, D.P., 2004. Mechanosensitive channels: multiplicity of families and gating paradigms. Sci STKE 2004, re4.