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Volumn 60, Issue 6, 2020, Pages 1154-1159

Clinical data for intravenous iron – debunking the hype around hypersensitivity

Author keywords

[No Author keywords available]

Indexed keywords

FERRIC CARBOXYMALTOSE; FERUMOXYTOL; IRON ISOMALTOSE; IRON SACCHARATE; ANTIANEMIC AGENT; IRON;

EID: 85085888575     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/trf.15837     Document Type: Article
Times cited : (24)

References (28)
  • 1
    • 85062733881 scopus 로고    scopus 로고
    • Patient blood management: recommendations from the 2018 Frankfurt Consensus Conference
    • ICC PBM Frankfurt 2018 Group
    • Mueller MM, Van Remoortel H, Meybohm P, et al. ICC PBM Frankfurt 2018 Group. Patient blood management: recommendations from the 2018 Frankfurt Consensus Conference. JAMA 2019;321:983-97.
    • (2019) JAMA , vol.321 , pp. 983-997
    • Mueller, M.M.1    Van Remoortel, H.2    Meybohm, P.3
  • 3
    • 79960617268 scopus 로고    scopus 로고
    • A comparative study of the physicochemical properties of iron isomaltoside 1000 (Monofer), a new intravenous iron preparation and its clinical implications
    • Jahn MR, Andreasen HB, Fütterer S, et al. A comparative study of the physicochemical properties of iron isomaltoside 1000 (Monofer), a new intravenous iron preparation and its clinical implications. Eur J Pharm Biopharm 2011;78:480-91.
    • (2011) Eur J Pharm Biopharm , vol.78 , pp. 480-491
    • Jahn, M.R.1    Andreasen, H.B.2    Fütterer, S.3
  • 4
    • 84908459097 scopus 로고    scopus 로고
    • Hypersensitivity reactions to intravenous iron: guidance for risk minimization and management
    • Rampton D, Folkersen J, Fishbane S, et al. Hypersensitivity reactions to intravenous iron: guidance for risk minimization and management. Haematologica 2014;99:1671-6.
    • (2014) Haematologica , vol.99 , pp. 1671-1676
    • Rampton, D.1    Folkersen, J.2    Fishbane, S.3
  • 5
    • 85000968659 scopus 로고    scopus 로고
    • Complement activation-related pseudo-allergy: a fresh look at hypersensitivity reactions to intravenous iron
    • Macdougall IC, Vernon K. Complement activation-related pseudo-allergy: a fresh look at hypersensitivity reactions to intravenous iron. Am J Nephrol 2017;45:60-2.
    • (2017) Am J Nephrol , vol.45 , pp. 60-62
    • Macdougall, I.C.1    Vernon, K.2
  • 6
    • 84872765093 scopus 로고    scopus 로고
    • Assessment of dextran antigenicity of intravenous iron products by an immunodiffusion assay
    • Neiser S, Wilhelm M, Schwarz K, et al. Assessment of dextran antigenicity of intravenous iron products by an immunodiffusion assay. Port J Nephrol Hypert 2011;25:219-24.
    • (2011) Port J Nephrol Hypert , vol.25 , pp. 219-224
    • Neiser, S.1    Wilhelm, M.2    Schwarz, K.3
  • 7
    • 85009509293 scopus 로고    scopus 로고
    • Reply to the letter to the editor by Johannes Ring and Rudi Valenta on the article “Assessment of dextran antigenicity of intravenous iron products by an immunodiffusion assay”
    • Neiser S, Schwarz K, Wilhelm M, et al. Reply to the letter to the editor by Johannes Ring and Rudi Valenta on the article “Assessment of dextran antigenicity of intravenous iron products by an immunodiffusion assay”. Port J Nephrol Hypert 2012;26:311-2.
    • (2012) Port J Nephrol Hypert , vol.26 , pp. 311-312
    • Neiser, S.1    Schwarz, K.2    Wilhelm, M.3
  • 8
    • 85085881285 scopus 로고    scopus 로고
    • Levels of Evidence Working Group. The Oxford 2011 Levels of Evidence
    • OCEBM Levels of Evidence Working Group. The Oxford 2011 Levels of Evidence. Available at: https://www.cebm.net/wp-content/uploads/2014/06/CEBM-Levels-of-Evidence-2.1.pdf.
  • 9
    • 85042412026 scopus 로고    scopus 로고
    • Comparative safety of intravenous ferumoxytol versus ferric carboxymaltose in iron deficiency anemia: a randomized trial
    • Adkinson NF, Strauss WE, Macdougall IC, et al. Comparative safety of intravenous ferumoxytol versus ferric carboxymaltose in iron deficiency anemia: a randomized trial. Am J Hematol 2018;93:683-90.
    • (2018) Am J Hematol , vol.93 , pp. 683-690
    • Adkinson, N.F.1    Strauss, W.E.2    Macdougall, I.C.3
  • 10
    • 85069823599 scopus 로고    scopus 로고
    • A prospective, multi-center, randomized comparison of iron isomaltoside 1000 versus iron sucrose in patients with iron deficiency anemia; the FERWON-IDA trial
    • Auerbach M, Henry D, Derman RJ, et al. A prospective, multi-center, randomized comparison of iron isomaltoside 1000 versus iron sucrose in patients with iron deficiency anemia; the FERWON-IDA trial. Am J Hematol 2019;94:1007-14.
    • (2019) Am J Hematol , vol.94 , pp. 1007-1014
    • Auerbach, M.1    Henry, D.2    Derman, R.J.3
  • 11
    • 85099171852 scopus 로고    scopus 로고
    • Safety and efficacy of iron isomaltoside 1000/ferric derisomaltose versus iron sucrose in patients with chronic kidney disease: the FERWON-NEPHRO randomized, open-label, comparative trial
    • [Epub ahead of print]
    • Bhandari S, Kalra PA, Berkowitz M, et al. Safety and efficacy of iron isomaltoside 1000/ferric derisomaltose versus iron sucrose in patients with chronic kidney disease: the FERWON-NEPHRO randomized, open-label, comparative trial. Nephrol Dial Transplant 2020. pii: gfaa011. https://doi.org/10.1093/ndt/gfaa011 [Epub ahead of print].
    • (2020) Nephrol Dial Transplant
    • Bhandari, S.1    Kalra, P.A.2    Berkowitz, M.3
  • 12
    • 85078905387 scopus 로고    scopus 로고
    • Effects of iron isomaltoside vs ferric carboxymaltose on hypophosphatemia in iron deficiency anemia: two randomized clinical trials
    • Wolf M, Rubin J, Achebe M, et al. Effects of iron isomaltoside vs ferric carboxymaltose on hypophosphatemia in iron deficiency anemia: two randomized clinical trials. JAMA 2020;323:432-43.
    • (2020) JAMA , vol.323 , pp. 432-443
    • Wolf, M.1    Rubin, J.2    Achebe, M.3
  • 13
    • 85086482131 scopus 로고    scopus 로고
    • Available from
    • Available from: www.clinicaltrials.gov.
  • 14
    • 84900833291 scopus 로고    scopus 로고
    • A phase III, randomized, open-label trial of ferumoxytol compared with iron sucrose for the treatment of iron deficiency anemia in patients with a history of unsatisfactory oral iron therapy
    • Hetzel D, Strauss W, Bernard K, et al. A phase III, randomized, open-label trial of ferumoxytol compared with iron sucrose for the treatment of iron deficiency anemia in patients with a history of unsatisfactory oral iron therapy. Am J Hematol 2014;89:646-50.
    • (2014) Am J Hematol , vol.89 , pp. 646-650
    • Hetzel, D.1    Strauss, W.2    Bernard, K.3
  • 15
    • 84904054374 scopus 로고    scopus 로고
    • A randomized comparison of ferumoxytol and iron sucrose for treating iron deficiency anemia in patients with CKD
    • Macdougall IC, Strauss WE, McLaughlin J, et al. A randomized comparison of ferumoxytol and iron sucrose for treating iron deficiency anemia in patients with CKD. Clin J Am Soc Nephrol 2014;9:705-12.
    • (2014) Clin J Am Soc Nephrol , vol.9 , pp. 705-712
    • Macdougall, I.C.1    Strauss, W.E.2    McLaughlin, J.3
  • 16
    • 85063794759 scopus 로고    scopus 로고
    • Ferumoxytol for iron deficiency anemia in patients undergoing hemodialysis. The FACT randomized controlled trial
    • Macdougall IC, Strauss WE, Dahl NV, et al. Ferumoxytol for iron deficiency anemia in patients undergoing hemodialysis. The FACT randomized controlled trial. Clin Nephrol 2019;91:237-45.
    • (2019) Clin Nephrol , vol.91 , pp. 237-245
    • Macdougall, I.C.1    Strauss, W.E.2    Dahl, N.V.3
  • 17
    • 85011025181 scopus 로고    scopus 로고
    • A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia
    • Derman R, Roman E, Modiano MR, et al. A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia. Am J Hematol 2017;92:286-91.
    • (2017) Am J Hematol , vol.92 , pp. 286-291
    • Derman, R.1    Roman, E.2    Modiano, M.R.3
  • 18
    • 85085889303 scopus 로고    scopus 로고
    • Medical review of Injectafer (VIT-45, ferric carboxymaltose injection; FCM) for the treatment of iron deficiency anemia (203565Orig1s000)
    • Center for Drug Evaluation and Research. Medical review of Injectafer (VIT-45, ferric carboxymaltose injection; FCM) for the treatment of iron deficiency anemia (203565Orig1s000). 2013. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/nda/2013/203565Orig1s000MedR.pdf.
    • (2013)
  • 19
    • 84920439896 scopus 로고    scopus 로고
    • The safety of intravenous iron preparations: systematic review and meta-analysis
    • Avni T, Bieber A, Grossman A, et al. The safety of intravenous iron preparations: systematic review and meta-analysis. Mayo Clin Proc 2015;90:12-23.
    • (2015) Mayo Clin Proc , vol.90 , pp. 12-23
    • Avni, T.1    Bieber, A.2    Grossman, A.3
  • 20
    • 85078567877 scopus 로고    scopus 로고
    • Indirect methods of comparison of the safety of ferric derisomaltose, iron sucrose and ferric carboxymaltose in the treatment of iron deficiency anemia
    • Pollock RF, Biggar P. Indirect methods of comparison of the safety of ferric derisomaltose, iron sucrose and ferric carboxymaltose in the treatment of iron deficiency anemia. Expert Rev Hematol 2020;13:187-95.
    • (2020) Expert Rev Hematol , vol.13 , pp. 187-195
    • Pollock, R.F.1    Biggar, P.2
  • 21
    • 84954382435 scopus 로고    scopus 로고
    • How we diagnose and treat iron deficiency anemia
    • Auerbach M, Adamson JW. How we diagnose and treat iron deficiency anemia. Am J Hematol 2016;91:31-8.
    • (2016) Am J Hematol , vol.91 , pp. 31-38
    • Auerbach, M.1    Adamson, J.W.2
  • 22
    • 85063670820 scopus 로고    scopus 로고
    • Canadian expert consensus: management of hypersensitivity reactions to intravenous iron in adults
    • Lim W, Afif W, Knowles S, et al. Canadian expert consensus: management of hypersensitivity reactions to intravenous iron in adults. Vox Sang 2019;114:363-73.
    • (2019) Vox Sang , vol.114 , pp. 363-373
    • Lim, W.1    Afif, W.2    Knowles, S.3
  • 23
    • 84973130364 scopus 로고    scopus 로고
    • Conference Participants. Iron management in chronic kidney disease: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference
    • Macdougall IC, Bircher AJ, Eckardt KU, et al. Conference Participants. Iron management in chronic kidney disease: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference. Kidney Int 2016;89:28-39.
    • (2016) Kidney Int , vol.89 , pp. 28-39
    • Macdougall, I.C.1    Bircher, A.J.2    Eckardt, K.U.3
  • 24
    • 79954432935 scopus 로고    scopus 로고
    • World Allergy Organization. World Allergy Organization guidelines for the assessment and management of anaphylaxis
    • Simons FE, Ardusso LR, Bilò MB, et al. World Allergy Organization. World Allergy Organization guidelines for the assessment and management of anaphylaxis. World Allergy Organ J 2011;4:13-37.
    • (2011) World Allergy Organ J , vol.4 , pp. 13-37
    • Simons, F.E.1    Ardusso, L.R.2    Bilò, M.B.3
  • 25
    • 85085880375 scopus 로고    scopus 로고
    • New recommendations to manage risk of allergic reactions with intravenous iron-containing medicines., [cited 2020 Jan 21]. Available from
    • European Medicines Agency. New recommendations to manage risk of allergic reactions with intravenous iron-containing medicines. 2013. [cited 2020 Jan 21]. Available from: https://www.ema.europa.eu/en/medicines/human/referrals/intravenous-iron-containing-medicinal-products.
    • (2013)
  • 26
    • 84904068210 scopus 로고    scopus 로고
    • Hypersensitivity from intravenous iron products
    • x-xi
    • Bircher AJ, Auerbach M. Hypersensitivity from intravenous iron products. Immunol Allergy Clin North Am 2014;34:707-23 x-xi.
    • (2014) Immunol Allergy Clin North Am , vol.34 , pp. 707-723
    • Bircher, A.J.1    Auerbach, M.2
  • 28
    • 85069935425 scopus 로고    scopus 로고
    • Incidence of hypophosphatemia in patients with inflammatory bowel disease treated with ferric carboxymaltose or iron isomaltoside
    • Detlie TE, Lindstrøm JC, Jahnsen ME, et al. Incidence of hypophosphatemia in patients with inflammatory bowel disease treated with ferric carboxymaltose or iron isomaltoside. Aliment Pharmacol Ther 2019;50:397-406.
    • (2019) Aliment Pharmacol Ther , vol.50 , pp. 397-406
    • Detlie, T.E.1    Lindstrøm, J.C.2    Jahnsen, M.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.