Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):A multi-center study in Wenzhou city, Zhejiang, China

Journal of Infection

Volumn 80, Issue 4, 2020, Pages 388-393

  Yang, Wenjie ^a   Cao, Qiqi ^a   Qin, Le ^a   Wang, Xiaoyang ^b   Cheng, Zenghui ^a   Pan, Ashan ^c   Dai, Jianyi ^d   Sun, Qingfeng ^b   Zhao, Fengquan ^d   Qu, Jieming ^a   Yan, Fuhua ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^c China   (China)

^d WENZHOU CENTRAL HOSPITAL   (China)

Author keywords

COVID 19; CT; Infection; Lung; Outside Hubei

Indexed keywords

C REACTIVE PROTEIN; OXYGEN;

ADULT; ARTICLE; CHINA; CLINICAL FEATURE; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTACT EXAMINATION; CONTROLLED STUDY; CORONAVIRUS DISEASE 2019; CORONAVIRUS INFECTION; COUGHING; DEMOGRAPHY; FEMALE; FEVER; FOLLOW UP; HEMOPTYSIS; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; LEUKOPENIA; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; OXYGEN SATURATION; RETROSPECTIVE STUDY; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; TRAVEL; BETACORONAVIRUS; CLINICAL TRIAL; COMPLICATION; DIAGNOSTIC IMAGING; LABORATORY TECHNIQUE; LUNG; MIDDLE AGED; MULTICENTER STUDY; PANDEMIC; PATHOPHYSIOLOGY; VIRUS PNEUMONIA; X-RAY COMPUTED TOMOGRAPHY;

ADULT; BETACORONAVIRUS; CHINA; CLINICAL LABORATORY TECHNIQUES; COHORT STUDIES; CORONAVIRUS INFECTIONS; COUGH; FEMALE; FEVER; HUMANS; LUNG; MALE; MIDDLE AGED; PANDEMICS; PNEUMONIA, VIRAL; RETROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED;

EID: 85081256500     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2020.02.016     Document Type: Article

References (27)

1. Zhu, N., Zhang, D., Wang, W., et al. A novel coronavirus from patients with pneumonia in China, 2019 [published online ahead of print, 2020 Jan 24]. N Engl J Med, 2020, 10.1056/NEJMoa2001017.
2. Huang, C., Wang, Y., Li, X., et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [published online ahead of print, 2020 Jan 24]. Lancet, 2020 S0140-6736(20)30183-5.
3. Li, Q., Guan, X., Wu, P., et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia [published online ahead of print, 2020 Jan 29]. N Engl J Med, 2020, 10.1056/NEJMoa2001316.
4. N. Chen, M. Zhou, X. Dong et al., Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. [published online ahead of print, 2020 Jan 29]. Lancet.
5. Chan, J.F., Yuan, S., Kok, K.H., et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster [published online ahead of print, 2020 Jan 24]. Lancet, 2020 S0140-6736(20)30154-9.
6. Wang, D., Hu, B., Hu, C., et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China [published online ahead of print, 2020 Feb 7]. JAMA, 2020, 10.1001/jama.2020.1585.
7. National health commission of the People's Republic of China. http://www.nhc.gov.cn/xcs/yqtb/202002/4a611bc7fa20411f8ba1c8084426c0d4.shtml.
8. Chang, D., Lin, M., Wei, L., et al. Epidemiologic and clinical characteristics of novel coronavirus infections involving 13 patients outside Wuhan, China [published online ahead of print, 2020 Feb 7]. JAMA, 2020, 10.1001/jama.2020.1623.
9. Wei-jie Guan, Zheng-yi Ni, Yu Hu, et al. Clinical characteristics of 2019 novel coronavirus infection in China. medRxiv2020.02.06.20020974.
10. Jones, K.E., Patel, N.G., Levy, M.A., Storeygard, A., Balk, D., et al. Global trends in emerging infectiousdiseases. Nature 451 (2008), 990–993.
11. Woolhouse, M.E., Haydon, D.T., Antia, R., Emerging pathogens: the epidemiology and evolution of species jumps. Trends Ecol Evol 20 (2005), 238–244.
12. Alizon, S., Hurford, A., Mideo, N., Van Baalen, M., Virulence evolution and the trade-off hypothesis:history, current state of affairs and the future. J Evol Biol 22 (2009), 245–259.
13. Mandell, L.A., Wunderink, R.G., Anzueto, A., Bartlett, J.G., Campbell, G.D., Dean, N.C., Infectious diseases society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis, 44(Suppl.2), 2007, S27e72.
14. Fine, M.J., Auble, T.E., Yealy, D.M., Hanusa, B.H., Weissfeld, L.A., Singer, D.E., et al. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med, 336, 1997, 243e50.
15. Lim, W.S., van der Eerden, M.M., Laing, R., Boersma, W.G., Karalus, N., Town, G.I., et al. Defining community-acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax, 58, 2003, 377e82.
16. Wong, K.T., Antonio, G.E., Hui, D.S., et al. Thin-section ct of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the disease. Radiology 228:2 (2003), 395–400.
17. Yongdao Zhou, Jianghu Dong. Statistical inference for coronavirus infected patients in Wuhan. medRxiv2020.02.10.20021774;.
18. Blumberg, S., Lloyd-Smith, J.O., Inference of R(0) and transmission heterogeneity from the size distribution of stuttering chains. PLoS Comput Biol, 9, 2013, e1002993.
19. Song, F., Shi, N., Shan, F., et al. Emerging Coronavirus 2019-nCoV Pneumonia [published online ahead of print, 2020 Feb 6]. Radiology, 2020, 200274.
20. Chung, M., Bernheim, A., Mei, X., et al. CT imaging features of 2019 novel coronavirus (2019-nCoV). Radiology, 2020, 200230 [published online ahead of print, 2020 Feb 4].
21. Müller, N.L., Ooi, G.C., Khong, P.L., Nicolaou, S, Severe acute respiratory syndrome: radiographic and CT findings. AJR Am J Roentgenol 181:1 (2003), 3–8.
22. Müller, N.L., Ooi, G.C., Khong, P.L., Zhou, L.J., Tsang, K.W., Nicolaou, S, High-resolution CT findings of severe acute respiratory syndrome at presentation and after admission. AJR Am J Roentgenol 182:1 (2004), 39–44.
23. Chan, M.S., Chan, I.Y., Fung, K.H., Poon, E., Yam, L.Y., Lau, K.Y, High-resolution CT findings in patients with severe acute respiratory syndrome: a pattern-based approach. AJR Am J Roentgenol 182:1 (2004), 49–56.
24. Wong, K.T., Antonio, G.E., Hui, D.S., et al. Thin-section CT of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the disease. Radiology 228:2 (2003), 395–400.
25. Ajlan, A.M., Ahyad, R.A., Jamjoom, L.G., Alharthy, A., Madani, T.A, Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings. AJR Am J Roentgenol 203:4 (2014), 782–787.
26. Das, K.M., Lee, E.Y., Langer, R.D., Larsson, S.G, Middle east respiratory syndrome coronavirus: what does a radiologist need to know?. AJR Am J Roentgenol 206:6 (2016), 1193–1201.
27. Xie, X., Zhong, Z., Zhao, W., Zheng, C., Wang, F., Liu, J, Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing. Radiology, 2020, 200343.