Alzheimer’s disease: Neurostructures

Learning and Memory: A Comprehensive Reference

Volumn , Issue , 2007, Pages 601-620

  Brickman, A M ^a   Buchsbaum, M S ^b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85079265701     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012370509-9.00099-1     Document Type: Chapter

References (194)

1. M. Albert Neuropsychological and neurophysiological changes in healthy adult humans across the age range Neurobiol. Aging 14 6 1993 623-625.
2. G.E. Alexander., K. Chen., T.L. Merkley., et al. Regional network of magnetic resonance imaging gray matter volume in healthy aging Neuroreport 17 10 2006 951-956.
3. G.E. Alexander., M.D. Crutcher Functional architecture of basal ganglia circuits: Neural substrates of parallel processing Trends Neurosci. 13 7 1990 266-271.
4. G.E. Alexander., M.R. DeLong., P.L. Strick Parallel organization of functionally segregated circuits linking basal ganglia and cortex Annu. Rev. Neurosci. 9 1986 357-381.
5. J.S. Allen., J. Bruss., C.K. Brown., H. Damasio Normal neuroanatomical variation due to age: The major lobes and a parcellation of the temporal region Neurobiol. Aging 26 9 2005 1245-1260 discussion 1279-1282.
6. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 4th edn. 1994 American Psychiatric Press Washington, DC.
7. L.G. Apostolova., I.D. Dinov., R.A. Dutton., et al. 3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer’s disease Brain 129 11 2006 2867-2873.
8. A. Ardila., M. Roselli Neuropsychological characteristics of normal aging Dev. Neuropsychol. 5 1989 307-320.
9. S.E. Arnold., B.T. Hyman., J. Flory., A.R. Damasio., G.W. Van Hoesen The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer’s disease Cereb. Cortex 1 1 1991 103-116.
10. M. Atiya., B.T. Hyman., M.S. Albert., R. Killiany Structural magnetic resonance imaging in established and prodromal Alzheimer disease: A review Alzheimer Dis. Assoc. Disord. 17 3 2003 177-195.
11. R. Au., J.M. Massaro., P.A. Wolf., et al. Association of white matter hyperintensity volume with decreased cognitive functioning: The Framingham Heart Study Arch. Neurol. 63 2 2006 246-250.
12. G.P. Band., K.R. Ridderinkhof., S. Segalowitz Explaining neurocognitive aging: Is one factor enough? Brain Cogn. 49 3 2002 259-267.
13. R. Barber., A. Gholkar., P. Scheltens., C. Ballard., I.G. McKeith., J.T. O’Brien Medial temporal lobe atrophy on MRI in dementia with Lewy bodies Neurology 52 6 1999 1153-1158.
14. G. Bartzokis Age-related myelin breakdown: A developmental model of cognitive decline and Alzheimer’s disease Neurobiol. Aging 25 1 2004 5-18 author reply 49-62.
15. G. Bartzokis., M. Beckson., P.H. Lu., K.H. Nuechterlein., N. Edwards., J. Mintz Age-related changes in frontal and temporal lobe volumes in men: A magnetic resonance imaging study Arch. Gen. Psychiatry 58 5 2001 461-465.
16. G. Bartzokis., J.L. Cummings., D. Sultzer., V.W. Henderson., K.H. Nuechterlein., J. Mintz White matter structural integrity in healthy aging adults and patients with Alzheimer disease: A magnetic resonance imaging study Arch. Neurol. 60 3 2003 393-398.
17. G. Bartzokis., P.H. Lu., J. Mintz Quantifying age-related myelin breakdown with MRI: Novel therapeutic targets for preventing cognitive decline and Alzheimer’s disease J. Alzheimers Dis. 6 6 supplement 2004 S53-S59.
18. G. Bartzokis., D. Sultzer., P. Lu., K. Nuechterlein., J. Mintz., J. Cummings Heterogeneous age-related breakdown of white matter structural integrity: Implications for cortical “disconnection” in aging and Alzheimer’s disease Neurobiol. Aging 25 7 2004 843-851.
19. M. Basso., J. Yang., L. Warren., et al. Volumetry of amygdala and hippocampus and memory performance in Alzheimer’s disease Psychiatry Res. 146 3 2006 251-261.
20. S. Bell-McGinty., O.L. Lopez., C.C. Meltzer., et al. Differential cortical atrophy in subgroups of mild cognitive impairment Arch. Neurol. 62 9 2005 1393-1397.
21. E.D. Bigler., B. Kerr., J. Victoroff., D.F. Tate., J.C. Breitner White matter lesions, quantitative magnetic resonance imaging, and dementia Alzheimer Dis. Assoc. Disord. 16 3 2002 161-170.
22. S.E. Black., S.D. Moffat., D.C. Yu., J. Parker., P. Stanchev., M. Bronskill Callosal atrophy correlates with temporal lobe volume and mental status in Alzheimer’s disease Can. J. Neurol. Sci. 27 3 2000 204-209.
23. D.D. Blatter., E.D. Bigler., S.D. Gale., et al. Quantitative volumetric analysis of brain MR: Normative database spanning 5 decades of life AJNR Am. J. Neuroradiol. 16 2 1995 241-251.
24. M. Bobinski., M.J. de Leon., A. Convit., et al. MRI of entorhinal cortex in mild Alzheimer’s disease Lancet 353 9146 1999 38-40.
25. M. Bobinski., J. Wegiel., H.M. Wisniewski., et al. Atrophy of hippocampal formation subdivisions correlates with stage and duration of Alzheimer disease Dementia 6 4 1995 205-210.
26. M. Bozzali., A. Falini., M. Franceschi., et al. White matter damage in Alzheimer’s disease assessed in vivo using diffusion tensor magnetic resonance imaging J. Neurol. Neurosurg. Psychiatry 72 6 2002 742-746.
27. H. Braak., E. Braak., J. Bohl Staging of Alzheimer-related cortical destruction Eur. Neurol. 33 6 1993 403-408.
28. K.M. Bradley., G.M. Bydder., M.M. Budge., et al. Serial brain MRI at 3-6 month intervals as a surrogate marker for Alzheimer’s disease Br. J. Radiol. 75 894 2002 506-513.
29. A.M. Brickman., M.S. Buchsbaum., L. Shihabuddin., E.A. Hazlett., J.C. Borod., R.C. Mohs Striatal size, glucose metabolic rate, and verbal learning in normal aging Brain Res. Cogn. Brain Res. 17 1 2003 106-116.
30. A.M. Brickman., M.S. Buchsbaum., L. Shihabuddin., et al. Age-associated change in orbital, cingulate, and dorsolateral frontal lobe gray and white matter volume [abstract] J. Int. Neuropsychol. Soc. 11 supplement 1 2005 176.
31. Brickman AM, Habeck C, Ramos MA, Scarmeas N, Stern Y (in press) A forward application of age associated gray and white matter networks. Hum. Brain Mapping.
32. A.M. Brickman., C. Habeck., E. Zarahn., J. Flynn., Y. Stern Structural MRI covariance patterns associated with normal aging and neuropsychological functioning Neurobiol. Aging 28 2 2007 284-295.
33. A.M. Brickman., M.E. Zimmerman., R.H. Paul., et al. Regional white matter and neuropsychological functioning across the adult lifespan Biol. Psychiatry 60 2006 444-453.
34. R.L. Buckner Memory and executive function in aging and AD: Multiple factors that cause decline and reserve factors that compensate Neuron 44 1 2004 195-208.
35. D.J. Callen., S.E. Black., F. Gao., C.B. Caldwell., J.P. Szalai Beyond the hippocampus: MRI volumetry confirms widespread limbic atrophy in AD Neurology 57 9 2001 1669-1674.
36. T.M. Chaim., F.L. Duran., R.R. Uchida., C.A. Périco., C.C. de Castro., G.F. Busatto Volumetric reduction of the corpus callosum in Alzheimer’s disease in vivo as assessed with voxel-based morphometry Psychiatry Res. 154 1 2007 59-68.
37. D. Chan., N.C. Fox., R. Jenkins., R.I. Scahill., W.R. Crum., M.N. Rossor Rates of global and regional cerebral atrophy in AD and frontotemporal dementia Neurology 57 10 2001 1756-1763.
38. D. Chan., N.C. Fox., R.I. Scahill., et al. Patterns of temporal lobe atrophy in semantic dementia and Alzheimer’s disease Ann. Neurol. 49 4 2001 433-442.
39. D. Chan., J.C. Janssen., J.L. Whitwell., et al. Change in rates of cerebral atrophy over time in early-onset Alzheimer’s disease: Longitudinal MRI study Lancet 362 9390 2003 1121-1122.
40. T. Chow., J. Cummings Frontal-subcortical circuits B. Miller., J. Cummings The Human Frontal Lobes: Functions and Disorders 1999 The Guilford Press New York 3-26.
41. A. Convit., A. Convit., J. de Asis., et al. Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer’s disease Neurobiol. Aging 21 1 2000 19-26.
42. I.A. Cook., A.F. Leuchter., M.L. Morgan., et al. Cognitive and physiologic correlates of subclinical structural brain disease in elderly healthy control subjects Arch. Neurol. 59 10 2002 1612-1620.
43. B.R. Copenhaver., L.A. Rabin., A.J. Saykin., et al. The fornix and mammillary bodies in older adults with Alzheimer’s disease, mild cognitive impairment, and cognitive complaints: A volumetric MRI study Psychiatry Res. 147 2-3 2006 93-103.
44. E. Courchesne., H.J. Chisum., J. Townsend., et al. Normal brain development and aging: Quantitative analysis at in vivo MR imaging in healthy volunteers Radiology 216 3 2000 672-682.
45. P.E. Cowell., B.I. Turetsky., R.C. Gur., R.I. Grossman., D.L. Shtasel., R.E. Gur Sex differences in aging of the human frontal and temporal lobes J. Neurosci. 14 8 1994 4748-4755.
46. J.G. Csernansky., L. Wang., S. Joshi., et al. Early DAT is distinguished from aging by high-dimensional mapping of the hippocampus. Dementia of the Alzheimer type Neurology 55 11 2000 1636-1643.
47. C.A. Cuénod., A. Denys., J.L. Michot., et al. Amygdala atrophy in Alzheimer’s disease. An in vivo magnetic resonance imaging study Arch. Neurol. 50 9 1993 941-945.
48. S. Daigneault., C.M. Braün., H.A. Whitaker An empirical test of two opposing theoretical models of prefrontal function Brain Cogn. 19 1 1992 48-71.
49. F.E. de Leeuw., J.C. de Groot., E. Achten., et al. Prevalence of cerebral white matter lesions in elderly people: A population based magnetic resonance imaging study. The Rotterdam Scan Study J. Neurol. Neurosurg. Psychiatry 70 1 2001 9-14.
50. M.J. de Leon., S.H. Ferris., I. Blau., et al. Correlations between computerised tomographic changes and behavioural deficits in senile dementia Lancet 2 8147 1979 859-860.
51. M.J. de Leon., L. Mosconi., K. Blennow., et al. Imaging and CSF studies in the preclinical diagnosis of Alzheimer’s disease Ann. N. Y. Acad. Sci. 1097 2007 114-145.
52. L. De Toledo-Morrell., I. Goncharova., B. Dickerson., R.S. Wilson., D.A. Bennett From healthy aging to early Alzheimer’s disease: In vivo detection of entorhinal cortex atrophy Ann. N. Y. Acad. Sci. 911 2000 240-253.
53. C. DeCarli., J. Massaro., D. Harvey., et al. Measures of brain morphology and infarction in the framingham heart study: Establishing what is normal Neurobiol. Aging 26 4 2005 491-510.
54. C. DeCarli., D.G. Murphy., J.A. Gillette., et al. Lack of age-related differences in temporal lobe volume of very healthy adults AJNR Am. J. Neuroradiol. 15 4 1994 689-696.
55. C. DeCarli., D.G. Murphy., A.R. McIntosh., D. Teichberg., M.B. Schapiro., B. Horwitz Discriminant analysis of MRI measures as a method to determine the presence of dementia of the Alzheimer type Psychiatry Res. 57 2 1995 119-130.
56. D.P. Devanand., G. Pradhaban., X. Liu., et al. Hippocampal and entorhinal atrophy in mild cognitive impairment: Prediction of Alzheimer disease Neurology 68 11 2007 828-836.
57. B.C. Dickerson., I. Goncharova., M.P. Sullivan., et al. MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer’s disease Neurobiol. Aging 22 5 2001 747-754.
58. A.T. Du., N. Schuff., D. Amend., et al. Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer’s disease J. Neurol. Neurosurg. Psychiatry 71 4 2001 441-447.
59. R. Elliott Executive functions and their disorders Br. Med. Bull. 65 2003 49-59.
60. F. Ezekiel., L. Chao., J. Kornak., et al. Comparisons between global and focal brain atrophy rates in normal aging and Alzheimer disease: Boundary Shift Integral versus tracing of the entorhinal cortex and hippocampus Alzheimer Dis. Assoc. Disord. 18 4 2004 196-201.
61. F. Fazekas., R. Kleinert., H. Offenbacher., et al. Pathologic correlates of incidental MRI white matter signal hyperintensities Neurology 43 9 1993 1683-1689.
62. A. Fellgiebel., P. Wille., M.J. Müller., et al. Ultrastructural hippocampal and white matter alterations in mild cognitive impairment: A diffusion tensor imaging study Dement. Geriatr. Cogn. Disord. 18 1 2004 101-108.
63. A.F. Fotenos., A.Z. Snyder., L.E. Girton., J.C. Morris., R.L. Buckner Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD Neurology 64 6 2005 1032-1039.
64. A.L. Foundas., C.M. Leonard., S.M. Mahoney., O.F. Agee., K.M. Heilman Atrophy of the hippocampus, parietal cortex, and insula in Alzheimer’s disease: A volumetric magnetic resonance imaging study Neuropsychiatry Neuropsychol. Behav. Neurol. 10 2 1997 81-89.
65. N.C. Fox., P.A. Freeborough., M.N. Rossor Visualisation and quantification of rates of atrophy in Alzheimer’s disease Lancet 348 9020 1996 94-97.
66. N.C. Fox., R.I. Scahill., W.R. Crum., M.N. Rossor Correlation between rates of brain atrophy and cognitive decline in AD Neurology 52 8 1999 1687-1689.
67. R.J. Franklin., C. Zhao., et al. Ageing and CNS remyelination Neuroreport 13 7 2002 923-928.
68. G.B. Frisoni., M.P. Laakso., F.J. Sim Hippocampal and entorhinal cortex atrophy in frontotemporal dementia and Alzheimer’s disease Neurology 52 1 1999 91-100.
69. T. Gómez-Isla., J.L. Price., D.W. McKeel., J.C. Morris., J.H. Growdon., B.T. Hyman Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer’s disease J. Neurosci. 16 14 1996 4491-4500.
70. C.D. Good., I.S. Johnsrude., J. Ashburner., R.N. Henson., K.J. Friston., R.S. Frackowiak A voxel-based morphometric study of ageing in 465 normal adult human brains Neuroimage 14 1 Pt 1 2001 21-36.
71. P.M. Greenwood The frontal aging hypothesis evaluated J. Int. Neuropsychol. Soc. 6 6 2000 705-726.
72. S.M. Grieve., L.M. Williams., R.H. Pauld., C.R. Clarke., E. Gordon Cognitive aging, executive function, and fractional anisotropy: A diffusion tensor MR imaging study AJNR Am. J. Neuroradiol. 28 2 2007 226-235.
73. F.M. Gunning-Dixon., D. Head., J. McQuain., J.D. Acker., N. Raz Differential aging of the human striatum: A prospective MR imaging study AJNR Am. J. Neuroradiol. 19 8 1998 1501-1507.
74. F.M. Gunning-Dixon., N. Raz The cognitive correlates of white matter abnormalities in normal aging: A quantitative review Neuropsychology 14 2 2000 224-232.
75. F.M. Gunning-Dixon., N. Raz Neuroanatomical correlates of selected executive functions in middle-aged and older adults: A prospective MRI study Neuropsychologia 41 14 2003 1929-1941.
76. J. Gunstad., R.H. Paul., A.M. Brickman., et al. Patterns of cognitive performance in middle-aged and older adults: A cluster analytic examination J. Geriatr. Psychiatry Neurol. 19 2 2006 59-64.
77. C.R. Guttmann., F.A. Jolesz., R. Kikinis., et al. White matter changes with normal aging Neurology 50 4 1998 972-978.
78. H. Hampel., S.J. Teipel., G.E. Alexander., et al. Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: A magnetic resonance imaging analysis Arch. Neurol. 55 2 1998 193-198.
79. M. Hashimoto., H. Kitagaki., T. Imamura., et al. Medial temporal and whole-brain atrophy in dementia with Lewy bodies: A volumetric MRI study Neurology 51 2 1998 357-362.
80. E.A. Hazlett., M.S. Buchsbaum., R.C. Mohs., et al. Age-related shift in brain region activity during successful memory performance Neurobiol. Aging 19 5 1998 437-445.
81. D. Head., R.L. Buckner., J.S. Shimony., et al. Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: Evidence from diffusion tensor imaging Cereb. Cortex 14 4 2004 410-423.
82. T. Hedden., J.D. Gabrieli Healthy and pathological processes in adult development: New evidence from neuroimaging of the aging brain Curr. Opin. Neurol. 18 6 2005 740-747.
83. B.T. Hyman., G.W. Van Hoesen., A.R. Damasio Memory-related neural systems in Alzheimer’s disease: An anatomic study Neurology 40 11 1990 1721-1730.
84. B.T. Hyman., G.W. Van Hoesen., A.R. Damasio., C.L. Barnes Alzheimer’s disease: Cell-specific pathology isolates the hippocampal formation Science 225 4667 1984 1168-1170.
85. M. Ikeda., H. Tanabe., Y. Nakagawa., et al. MRI-based quantitative assessment of the hippocampal region in very mild to moderate Alzheimer’s disease Neuroradiology 36 1 1994 7-10.
86. C.R. Jack Jr., R.C. Petersen., Y.C. Xu., et al. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer’s disease Neurology 49 3 1997 786-794.
87. C.R. Jack Jr., R.C. Petersen., Y. Xu., et al. Rate of medial temporal lobe atrophy in typical aging and Alzheimer’s disease Neurology 51 4 1998 993-999.
88. C.R. Jack Jr., R.C. Petersen., Y.C. Xu., et al. Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment Neurology 52 7 1999 1397-1403.
89. C.R. Jack., R.C. Petersen., Y. Xu., et al. Rates of hippocampal atrophy correlate with change in clinical status in aging and AD Neurology 55 4 2000 484-489.
90. J.S. Janowsky., J.A. Kaye., R.A. Carper Atrophy of the corpus callosum in Alzheimer’s disease versus healthy aging J. Am. Geriatr. Soc. 44 7 1996 798-803.
91. T.L. Jernigan., S.L. Archibald., M.T. Berhow., E.R. Sowell., D.S. Foster., J.R. Hesselink Cerebral structure on MRI, Part I: Localization of age-related changes Biol. Psychiatry 29 1 1991 55-67.
92. K. Juottonen., M.P. Laakso., R. Insausti., et al. Volumes of the entorhinal and perirhinal cortices in Alzheimer’s disease Neurobiol. Aging 19 1 1998 15-22.
93. R.N. Kalaria Vascular factors in Alzheimer’s disease Int. Psychogeriatr. 15 supplement 1 2003 47-52.
94. G.B. Karas., P. Scheltens., S.A. Rombouts., et al. Global and local gray matter loss in mild cognitive impairment and Alzheimer’s disease Neuroimage 23 2 2004 708-716.
95. J.A. Kaye., T. Swihart., D. Howieson., et al. Volume loss of the hippocampus and temporal lobe in healthy elderly persons destined to develop dementia Neurology 48 5 1997 1297-1304.
96. J.P. Kesslak., O. Nalcioglu., C.W. Cotman Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer’s disease Neurology 41 1 1991 51-54.
97. D. Kidron., S.E. Black., P. Stanchev., et al. Quantitative MR volumetry in Alzheimer’s disease. Topographic markers and the effects of sex and education Neurology 49 6 1997 1504-1512.
98. R.J. Killiany., T. Gómez-Isla., M. Moss., et al. Use of structural magnetic resonance imaging to predict who will get Alzheimer’s disease Ann. Neurol. 47 4 2000 430-439.
99. R.J. Killiany., B.T. Hyman., T. Gomez-Isla., et al. MRI measures of entorhinal cortex vs hippocampus in preclinical AD Neurology 58 8 2002 1188-1196.
100. R.J. Killiany., M.B. Moss., M.S. Albert., et al. Temporal lobe regions on magnetic resonance imaging identify patients with early Alzheimer’s disease Arch. Neurol. 50 9 1993 949-954.
101. J.S. Krasuski., G.E. Alexander., B. Horwitz., et al. Volumes of medial temporal lobe structures in patients with Alzheimer’s disease and mild cognitive impairment (and in healthy controls) Biol. Psychiatry 43 1 1998 60-68.
102. K.R. Krishnan., M.M. Husain., W.M. McDonald., et al. In vivo stereological assessment of caudate volume in man: Effect of normal aging Life Sci. 47 15 1990 1325-1329.
103. M.P. Laakso., H. Soininen., K. Partanen., et al. MRI of the hippocampus in Alzheimer’s disease: Sensitivity, specificity, and analysis of the incorrectly classified subjects Neurobiol. Aging 19 1 1998 23-31.
104. G. Lafleche., M.S. Albert Executive function deficits in mild Alzheimer’s disease Neuropsychology 9 1995 313-320.
105. S. Larrieu., L. Letenneur., J.M. Orgogozo., et al. Incidence and outcome of mild cognitive impairment in a population-based prospective cohort Neurology 59 10 2002 1594-1599.
106. L.J. Launer Demonstrating the case that AD is a vascular disease: Epidemiologic evidence Ageing Res. Rev. 1 1 2002 61-77.
107. S. Lehericy., M. Baulac., J. Chiras., et al. Amygdalohippocampal MR volume measurements in the early stages of Alzheimer disease AJNR Am. J. Neuroradiol. 15 5 1994 929-937.
108. M. Lezak Neuropsychological Assessment 3rd edn. 1995 Oxford University Press New York.
109. D. Lichter., J. Cummings Frontal-Subcortical Circuits in Psychiatric and Neurological Disorders 2001 Guilford Press New York.
110. D.W. Loring INS Dictionary of Neuropyschology 1999 Oxford University Press New York.
111. S.E. MacPherson., L.H. Phillips., S. Della Sala Age, executive function, and social decision making: A dorsolateral prefrontal theory of cognitive aging Psychol. Aging 17 4 2002 598-609.
112. D.J. Madden., W.L. Whiting., S.A. Huettel., L.E. White., J.R. MacFall., J.M. Provenzale Diffusion tensor imaging of adult age differences in cerebral white matter: Relation to response time Neuroimage 21 3 2004 1174-1181.
113. P. Malloy., S. Correia., G. Stebbins., D.H. Laidlaw Neuroimaging of white matter in aging and dementia Clin. Neuropsychol. 21 1 2007 73-109.
114. H. Matsuda., S. Mizumura., T. Nagao., et al. An easy Z-score imaging system for discrimination between very early Alzheimer’s disease and controls using brain perfusion SPECT in a multicentre study Nucl. Med. Commun. 28 3 2007 199-205.
115. W.M. McDonald., M. Husain., P.M. Doraiswamy., G. Figiel., O. Boyko., K.R. Krishnan A magnetic resonance image study of age-related changes in human putamen nuclei Neuroreport 2 1 1991 57-60.
116. G. McKhann., D. Drachman., M. Folstein., R. Katzman., D. Price., E.M. Stadlan Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer’s Disease Neurology 34 1984 939-944.
117. S. Minoshima., N.L. Foster., E.C. Petrie., R.L. Albin., K.A. Frey., D.E. Kuhl Neuroimaging in dementia with Lewy bodies: Metabolism, neurochemistry, and morphology J. Geriatr. Psychiatry Neurol. 15 4 2002 200-209.
118. A.U. Monsch., M.W. Bondi., N. Butters., D.P. Salmon., R. Katzman., L.J. Thal Comparisons of verbal fluency tasks in the detection of dementia of the Alzheimer type Arch. Neurol. 49 12 1992 1253-1258.
119. J.C. Morris., M. Storandt., J.P. Miller., et al. Mild cognitive impairment represents early stage Alzheimer’s disease Arch. Neurol. 58 2001 1705-1706.
120. L. Mosconi., M. Brys., L. Glodzik-Sobanskaa., S. De Santia., H. Rusineka., M.J. de Leon Early detection of Alzheimer’s disease using neuroimaging Exp. Gerontol. 42 1-2 2007 129-138.
121. Q. Mu., J. Xie., Z. Wen., Y. Weng., Z. Shuyun A quantitative MR study of the hippocampal formation, the amygdala, and the temporal horn of the lateral ventricle in healthy subjects 40 to 90 years of age AJNR Am. J. Neuroradiol. 20 2 1999 207-211.
122. D. Mungas., W.J. Jagust., B.R. Reed., et al. MRI predictors of cognition in subcortical ischemic vascular disease and Alzheimer’s disease Neurology 57 12 2001 2229-2235.
123. D.G. Murphy., C. DeCarli., A.R. McIntosh., et al. Sex differences in human brain morphometry and metabolism: An in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging Arch. Gen. Psychiatry 53 7 1996 585-594.
124. D.G. Murphy., C. DeCarli., M.B. Schapiro., S.I. Rapoport., B. Horwitz Age-related differences in volumes of subcortical nuclei, brain matter, and cerebrospinal fluid in healthy men as measured with magnetic resonance imaging Arch. Neurol. 49 8 1992 839-845.
125. D.G. Murphy., C.D. DeCarli., E. Daly., et al. Volumetric magnetic resonance imaging in men with dementia of the Alzheimer type: Correlations with disease severity Biol. Psychiatry 34 9 1993 612-621.
126. O. Naggara., C. Oppenheim., D. Rieu., et al. Diffusion tensor imaging in early Alzheimer’s disease Psychiatry Res. 146 3 2006 243-249.
127. A.O. Nusbaum., C.Y. Tang., M.S. Buchsbaum., T.C. Wei., S.W. Atlas Regional and global changes in cerebral diffusion with normal aging AJNR Am. J. Neuroradiol. 22 1 2001 136-142.
128. J.T. O’Brien., S. Paling., R. Barber., et al. Progressive brain atrophy on serial MRI in dementia with Lewy bodies, AD, and vascular dementia Neurology 56 10 2001 1386-1388.
129. T. Ohnishi., H. Matsuda., T. Tabira., T. Asada., M. Uno Changes in brain morphology in Alzheimer disease and normal aging: Is Alzheimer disease an exaggerated aging process? AJNR Am. J. Neuroradiol. 22 9 2001 1680-1685.
130. M. O’Sullivan., D.K. Jones., P.E. Summers., R.G. Morris., S.C.R. Williams., H.S. Markus Evidence for cortical “disconnection” as a mechanism of age-related cognitive decline Neurology 57 4 2001 632-638.
131. J. Pantel., J. Schröder., M. Jauss., et al. Topography of callosal atrophy reflects distribution of regional cerebral volume reduction in Alzheimer’s disease Psychiatry Res. 90 3 1999 181-192.
132. C. Pennanen., M. Kivipelto., S. Tuomainen., et al. Hippocampus and entorhinal cortex in mild cognitive impairment and early AD Neurobiol. Aging 25 3 2004 303-310.
133. A. Peters The effects of normal aging on myelin and nerve fibers: A review J. Neurocytol. 31 8-9 2002 581-593.
134. A. Peters., D.L. Rosene In aging, is it gray or white? J. Comp. Neurol. 462 2 2003 139-143.
135. R.C. Petersen Mild cognitive impairment as a diagnostic entity J. Intern. Med. 256 3 2004 183-194.
136. R.C. Petersen Mild cognitive impairment: Current research and clinical implications Semin. Neurol. 27 1 2007 22-31.
137. R.C. Petersen., J.C. Morris Mild cognitive impairment as a clinical entity and treatment target Arch. Neurol. 62 7 2005 1160-1163 discussion 1167.
138. R.C. Petersen., G.E. Smith., S.C. Waring., R.J. Ivnik., E.G. Tangalos., E. Kokmen Mild cognitive impairment: Clinical characterization and outcome Arch. Neurol. 56 3 1999 303-308.
139. R.C. Petersen., J.C. Stevens., M. Ganguli., E.G. Tangalos., J.L. Cummings., S.T. DeKosky Practice parameter: Early detection of dementia: Mild cognitive impairment (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology Neurology 56 9 2001 1133-1142.
140. A. Pfefferbaum., E. Adalsteinsson., E.V. Sullivan Frontal circuitry degradation marks healthy adult aging: Evidence from diffusion tensor imaging Neuroimage 26 3 2005 891-899.
141. A. Pfefferbaum., E.V. Sullivan Increased brain white matter diffusivity in normal adult aging: Relationship to anisotropy and partial voluming Magn. Reson. Med. 49 5 2003 953-961.
142. N.D. Prins., E.J. van Dijk., T. den Heijer., et al. Cerebral white matter lesions and the risk of dementia Arch. Neurol. 61 10 2004 1531-1534.
143. J.C. Pruessner., D.L. Collins., M. Pruessner., A.C. Evans Age and gender predict volume decline in the anterior and posterior hippocampus in early adulthood J. Neurosci. 21 1 2001 194-200.
144. A. Ramani., J.H. Jensen., J.A. Helpern Quantitative MR imaging in Alzheimer disease Radiology 241 1 2006 26-44.
145. N. Raz Aging of the brain and its impact on cognitive performance: Integration of structural and functional findings F.I.M. Craik., T.A. Salthouse Handbook of Aging and Cognition 2000 Erlbaum Mahwah, NJ 1-90.
146. N. Raz The aging brain in vivo: Differential changes and their modifiers R. Cabeza., L. Nyberg. D.C. Park Cognitive Neuroscience of Aging: Linking Cognitive and Cerebral Aging 2004 Oxford University Press New York 17-55.
147. N. Raz., F.M. Gunning., D. Head., et al. Selective aging of the human cerebral cortex observed in vivo: Differential vulnerability of the prefrontal gray matter Cereb. Cortex 7 3 1997 268-282.
148. N. Raz., F.M. Gunning-Dixon., D. Head., J.H. Dupuis., J.D. Acker Neuroanatomical correlates of cognitive aging: Evidence from structural magnetic resonance imaging Neuropsychology 12 1 1998 95-114.
149. N. Raz., U. Lindenberger., K.M. Rodrigue., et al. Regional brain changes in aging healthy adults: General trends, individual differences and modifiers Cereb. Cortex 15 11 2005 1676-1689.
150. N. Raz., K.M. Rodrigue Differential aging of the brain: Patterns, cognitive correlates and modifiers Neurosci. Biobehav. Rev. 30 6 2006 730-748.
151. N. Raz., K.M. Rodrigue., D. Head., K.M. Kennedy., J.C. Acker Differential aging of the medial temporal lobe: A study of a five-year change Neurology 62 3 2004 433-438.
152. N. Raz., I.J. Torres., J.D. Acker Age, gender, and hemispheric differences in human striatum: A quantitative review and new data from in vivo MRI morphometry Neurobiol. Learn. Mem. 63 2 1995 133-142.
153. N. Raz., A. Williamson., F. Gunning-Dixon., D. Head., J.D. Acker Neuroanatomical and cognitive correlates of adult age differences in acquisition of a perceptual-motor skill Microsc. Res. Tech. 51 1 2000 85-93.
154. N.L. Rempel-Clower., S.M. Zola., L.R. Squire., D.G. Amaral Three cases of enduring memory impairment after bilateral damage limited to the hippocampal formation J. Neurosci. 16 16 1996 5233-5255.
155. S.M. Resnick., A.F. Goldszal., C. Davatzikos., et al. One-year age changes in MRI brain volumes in older adults Cereb. Cortex 10 5 2000 464-472.
156. S.M. Resnick., D.L. Pham., M.A. Kraut., A.B. Zonderman., C. Davatzikos Longitudinal magnetic resonance imaging studies of older adults: A shrinking brain J. Neurosci. 23 8 2003 3295-3301.
157. B.H. Ridha., J. Barnes., A. Bartlett., et al. Tracking atrophy progression in familial Alzheimer’s disease: A serial MRI study Lancet Neurol. 5 10 2006 828-834.
158. K. Ritchie., S. Artero., J. Touchon Classification criteria for mild cognitive impairment: A population-based validation study Neurology 56 1 2001 37-42.
159. H. Rusinek., M.J. de Leon., A.E. George., et al. Alzheimer disease: Measuring loss of cerebral gray matter with MR imaging Radiology 178 1 1991 109-114.
160. D.H. Salat., J.A. Kaye., J.S. Janowsky Prefrontal gray and white matter volumes in healthy aging and Alzheimer disease Arch. Neurol. 56 3 1999 338-344.
161. D.H. Salat., D.S. Tuch., D.N. Greve Age-related alterations in white matter microstructure measured by diffusion tensor imaging Neurobiol. Aging 26 8 2005 1215-1227.
162. D.P. Salmon., R.G. Thomas., M.M. Pay., et al. Alzheimer’s disease can be accurately diagnosed in very mildly impaired individuals Neurology 59 7 2002 1022-1028.
163. P. Scheltens., F. Barkhof., J. Valk., et al. White matter lesions on magnetic resonance imaging in clinically diagnosed Alzheimer’s disease: Evidence for heterogeneity Brain 115 3 1992 735-748.
164. J.M. Schott., N.C. Fox., C. Frost., et al. Assessing the onset of structural change in familial Alzheimer’s disease Ann. Neurol. 53 2 2003 181-188.
165. S.A. Scott., S.T. DeKosky., S.W. Scheff Volumetric atrophy of the amygdala in Alzheimer’s disease: Quantitative serial reconstruction Neurology 41 3 1991 351-356.
166. W.B. Scoville., B. Milner Loss of recent memory after bilateral hippocampal lesions J. Neurol. Neurosurg. Psychiatry 20 1 1957 11-21.
167. J.P. Seab., W.J. Jagust., S.T. Wong., M.S. Roos., B.R. Reed., T.F. Budinger Quantitative NMR measurements of hippocampal atrophy in Alzheimer’s disease Magn. Reson. Med. 8 2 1988 200-208.
168. I. Skoog Vascular aspects in Alzheimer’s disease J. Neural Transm. Suppl. 59 2000 37-43.
169. S.A. Small Age-related memory decline: Current concepts and future directions Arch. Neurol. 58 3 2001 360-364.
170. R. Stahl., O. Dietrich., S.J. Teipel., H. Hampel., M.F. Reiser., S.O. Schoenberg White matter damage in Alzheimer disease and mild cognitive impairment: Assessment with diffusion-tensor MR imaging and parallel imaging techniques Radiology 243 2 2007 483-492.
171. E.V. Sullivan., L. Marsh., D.H. Mathalon., K.O. Lim., A. Pfefferbaum Age-related decline in MRI volumes of temporal lobe gray matter but not hippocampus Neurobiol. Aging 16 4 1995 591-606.
172. E.V. Sullivan., A. Pfefferbaum Diffusion tensor imaging and aging Neurosci. Biobehav. Rev. 30 6 2006 749-761.
173. E.V. Sullivan., M. Rosenbloom., K.L. Serventi., A. Pfefferbaum Effects of age and sex on volumes of the thalamus, pons, and cortex Neurobiol. Aging 25 2 2004 185-192.
174. T. Suzuki., N. Iwata., Y. Kitamura., et al. Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia Am. J. Med. Genet. B Neuropsychiatr. Genet. 121 1 2003 7-13.
175. S. Takahashi., H. Yonezawa., J. Takahashi., M. Kudo., T. Inoue., H. Tohgi Selective reduction of diffusion anisotropy in white matter of Alzheimer disease brains measured by 3.0 Tesla magnetic resonance imaging Neurosci. Lett. 332 1 2002 45-48.
176. J.L. Tanabe., D. Amend., N. Schuff., et al. Tissue segmentation of the brain in Alzheimer disease AJNR Am. J. Neuroradiol. 18 1 1997 115-123.
177. S.J. Teipel., W. Bayer., G.E. Alexander., et al. Progression of corpus callosum atrophy in Alzheimer disease Arch. Neurol. 59 2 2002 243-248.
178. P.M. Thompson., K.M. Hayashi., et al. Dynamics of gray matter loss in Alzheimer’s disease J. Neurosci. 23 3 2003 994-1005.
179. P.M. Thompson., K.M. Hayashi., G. Zubicaray., et al. Mapping hippocampal and ventricular change in Alzheimer disease Neuroimage 22 4 2004 1754-1766.
180. D.J. Tisserand., J.C. Pruessner., E.J. Sanz Arigita., et al. Regional frontal cortical volumes decrease differentially in aging: An MRI study to compare volumetric approaches and voxel-based morphometry Neuroimage 17 2 2002 657-669.
181. D.J. Tisserand., M.P. van Boxtel., J.C. Pruessner., et al. A voxel-based morphometric study to determine individual differences in gray matter density associated with age and cognitive change over time Cereb. Cortex 14 9 2004 966-973.
182. L. Tsai., M.T. Tsuang The Mini-Mental State Test and computerized tomography Am. J. Psychiatry 136 4A 1979 436-438.
183. W.M. van der Flier., H.A. Middelkoop., W.E. Weverling-Rijnsburger., et al. Interaction of medial temporal lobe atrophy and white matter hyperintensities in AD Neurology 62 10 2004 1862-1864.
184. C. Van Petten Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: Review and meta-analysis Neuropsychologia 42 10 2004 1394-1413.
185. S.E. Vermeer., N.D. Prins., T. den Heijer., A. Hofman., P.J. Koudstaal., M.M.B. Breteler Silent brain infarcts and the risk of dementia and cognitive decline N. Engl. J. Med. 348 13 2003 1215-1222.
186. P.J. Visser., P. Scheltens., F.R. Verhey., et al. Medial temporal lobe atrophy and memory dysfunction as predictors for dementia in subjects with mild cognitive impairment J. Neurol. 246 6 1999 477-485.
187. P.J. Visser., F.R.J. Verhey., P.A.M. Hofman., P. Scheltens., J. Jolles Medial temporal lobe atrophy predicts Alzheimer’s disease in patients with minor cognitive impairment J. Neurol. Neurosurg. Psychiatry 72 4 2002 491-497.
188. K. Welsh., N. Butters., J. Hughes., R. Mohs., A. Heyman Detection of abnormal memory decline in mild cases of Alzheimer’s disease using CERAD neuropsychological measures Arch. Neurol. 48 3 1991 278-281.
189. R. West In defense of the frontal lobe hypothesis of cognitive aging J. Int. Neuropsychol. Soc. 6 6 2000 727-729 discussion 730.
190. R.L. West An application of prefrontal cortex function theory to cognitive aging Psychol. Bull. 120 2 1996 272-292.
191. W. Whelihan., E. Lesher Neuropsychological changes in frontal functions with aging Dev. Neuropsychol. 1 1985 371-380.
192. H. Wolf., A. Hensel., M. Hund-Georgiadis., et al. Structural correlates of mild cognitive impairment Neurobiol. Aging 25 7 2004 913-924.
193. Y. Xu., C.R. Jack Jr., P.C. O’Brien., et al. Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD Neurology 54 9 2000 1760-1767.
194. M.E. Zimmerman., A.M. Brickman., R.H. Paul., et al. The relationship between frontal gray matter volume and cognition varies across the healthy adult lifespan Am. J. Geriatr. Psychiatry 14 10 2006 823-833.