Simultaneous two-photon excitation of photodynamic therapy agents

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 3269, Issue , 1998, Pages 68-75

  Wachter, E A ^a,b   Partridge, W P ^a   Fisher, W G ^a,b   Dees, H C ^b   Petersen, M G ^c  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b Photogen Inc   (United States)

^c UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Pdt; Photochemistry; Photodynamic therapy; Spectroscopy; Titanium:sapphire; Tpe; Two photon excitation

Indexed keywords

INFRARED DEVICES; LASER EXCITATION; PARTICLE BEAMS; PHOTOCHEMICAL REACTIONS; PHOTODYNAMIC THERAPY; PHOTONS; PULSE REPETITION RATE; SAPPHIRE; SPECTROSCOPY; THERMOPLASTIC ELASTOMERS; TITANIUM; ULTRAFAST LASERS;

EXCITED-STATE PROPERTIES; EXTREMELY SHORT PULSE; PHOTOCHEMICAL PROPERTIES; PHOTODYNAMIC THERAPY (PDT); SINGLE PHOTON EXCITATION; TITANIUM:SAPPHIRE LASERS; TWO-PHOTON EXCITATIONS; ULTRA VIOLET EXCITATION;

EXCITED STATES;

EID: 85076745334     PISSN: 0277786X     EISSN: 1996756X     Source Type: Conference Proceeding    
DOI: 10.1117/12.312332     Document Type: Conference Paper

References (19)

1. J.C. Kennedy, R.H. Pottier andD.C. Ross, "Photodynamic therapy with endogenous protoporphyrin IX; basic principles and present clinical experience", I Photochem. Photobiol. B: Biology. 6, pp. 143-148, 1990.
2. A.M.R. Fisher, A.L. Murphree and C.J. Gomer, "Clinical and preclinicalphotodynamic therapy", Lasers Surg. Med. 17, pp. 2-31, 1995.
3. W-F Cheong, S.A. Prahl and A.J. Welch, "A review ofthe opticalproperties ofbiological tissues", IEEEJ. Quant. Electron. 26, pp. 2166-2185, 1990.
4. D. Dolphin, "1993 Syntex award lecture, photomedicine and photodynamic therapy", Can. J. Chem. 72, pp. 1005-1013, 1994.
5. W.G. Fisher, E.A. Wachter, M. Armas and C. Seaton, "The titanium:sapphire laser as an excitation source in two-photon spectroscopy", Appl. Spectrosc. 51, pp. 218-226, 1997.
6. W.G. Fisher, E.A. Wachter, F.E. Lytle, M. Armas and C. Seaton, "Source-corrected two-photon excited fluorescence measurements between 700 and 880 mm", Appl. Spectrosc. (in press-April 1998).
7. D.H. Oh, R.J. Stanley, M. Lin, W.K. Hoeffer, S.G. Boxer, M.W. Berns and E.A. Bauer, "Two-photon excitation of 4'-hydroxymethyl-4,5',8-Trimethylpsoralen", Photochem. Photobiol. 65, pp. 91-95, 1997.
8. W.G. Fisher, W.P. Partridge, Jr., C. Dees and E.A. Wachter, "Simultaneous two-photon activation oftype-I PDT agents", Photochem. Photobiol. 66, pp. 141-155, 1997.
9. K.R. Weishaupt, C.G. Gomer and T.J. Dougherty, "Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor", Cancer Res. 36, pp. 2326-2329, 1976.
10. T. Patrice, M-F. Le Bodic, L.Le Bodic, T. Spreux, G. Dabouis and L. Hervouet, "Neodymium-yttrium aluminum garnet laser destruction ofnonsensitized and hematoporphyrin derivative-sensitized tumors", Canc. Res. 43, pp. 2876-2879, 1983.
11. R.S. Bodaness and D.S. King, "The two-photon induced fluorescence of the tumor localizing photosensitizer hematoporphyrin derivative via 1064 ninphotons from a 20 ns Q-switchedND-YAG laser", Biochem. Biophys. Res. Comm. 126, pp. 346-351, 1985.
12. R.S. Bodaness, D.F. Heller, J. Krasinsky andD.S. King, "Thetwo-photonlaser-inducedfluorescence ofthe tumor-localizing photosensitizer hematoporphyrin derivative", J. Biol. Chem. 261, pp. 12098-12101, 1986.
13. R.E. Marchesini, Melloni, G. Pezzoni, G. Savi, F. Zunino, F. Docchio and G. Fava, "A study on the possible involvement ofnonlinear mechanism oflight absorption by HpD with Nd:YAG laser", Lasers Surg. Med. 6, pp. 323-327, 1986.
14. P. Lenz, "In vivo excitation ofphotosensitizers by infrared light", Photochem. Photobiol. 62, pp. 333-338. 1995.
15. FE. Lytle, T.L. Hassinger and M.C. Johnson, "Two-photon excitation spectra ofpolycyclic aromatic hydrocarbons", Intern. J. Environ. Anal. Chem. 8, pp. 303-312, 1980.
16. W.L. Peticolas, "Multiphoton spectroscopy", Ann. Rev. Phys. Chem. 18, pp. 233-260, 1967.
17. B.C. Wilson and M.S. Patterson, "The physics ofphotodynamic therapy", Phys. Med. Biol. 31, pp. 327-360, 1986.
18. M.H. Niemz, "Threshold dependence of laser-inducedoptical breakdown on pulse duration", Appl.Phys. Lett. 66,pp. 118 1-1183, 1995.
19. D.X. Hammer, R.J. Thomas, G.D. Noojin, B.A. Rockwell, P.K. Kennedy, and W.P. Roach, "Experimental investigation of ultrashort pulse laser-induced breakdown thresholds in aqueous media", IEEE J. Quant. Electron. 32, pp. 670-678, 1996.