Bilobalide and PC12 cells: A structure activity relationship study

Bioorganic and Medicinal Chemistry

Volumn 28, Issue 2, 2020, Pages

  Usuki, Toyonobu ^a   Yoshimoto, Yukiko ^a   Sato, Makiko ^a   Takenaka, Tae ^a   Takezawa, Ryota ^a   Yoshida, Yusuke ^b   Satake, Masayuki ^c   Suzuki, Noriyuki ^a   Hashizume, Daisuke ^d   Dzyuba, Sergei V ^e  

^a SOPHIA UNIVERSITY   (Japan)

^b Adjusted Cell Experiment Laboratory Inc   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d RIKEN Center for Emergent Matter Science   (Japan)

^e TEXAS CHRISTIAN UNIVERSITY   (United States)

Author keywords

Bilobalide; Derivatization; PC12; SAR; Terpene trilactone

Indexed keywords

10,12 DI O (P BROMOBENZOYL) ISOBILOBALIDE; 10,12 DI O ACETYL ISOBILOBALIDE; AMYLOID BETA PROTEIN[1-40]; BILOBALIDE; BILOBALIDE DIETHER; BILOBALIDE TRILACTOL; DIBN BILOBALIDE ALDEHYDE; GINKGOLIDE; LACTONE DERIVATIVE; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; CYCLOPENTANE DERIVATIVE; FURAN DERIVATIVE; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELL ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DERIVATIZATION; DISEASE EXACERBATION; DRUG ISOLATION; DRUG SCREENING; NEURITE OUTGROWTH; NEUROPROTECTION; NONHUMAN; PC12 CELL LINE (PHEOCHROMOCYTOMA); RAT; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; ISOLATION AND PURIFICATION; MOLECULAR MODEL; NERVE CELL; PC12 CELL LINE;

AMYLOID BETA-PEPTIDES; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CRYSTALLOGRAPHY, X-RAY; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; FURANS; GINKGOLIDES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEURONS; NEUROPROTECTIVE AGENTS; PC12 CELLS; PEPTIDE FRAGMENTS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85076546440     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2019.115251     Document Type: Article

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