Clinical presentation, treatment, and short-term outcomes of lung injury associated with e-cigarettes or vaping: a prospective observational cohort study

The Lancet

Volumn 394, Issue 10214, 2019, Pages 2073-2083

  Blagev, Denitza P ^a,c   Harris, Dixie ^a,b   Dunn, Angela C ^d   Guidry, David W ^a,b   Grissom, Colin K ^a,c   Lanspa, Michael J ^a  

^a INTERMOUNTAIN HEALTHCARE   (United States)

^b Occupational Pulmonary Medicine   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UTAH DEPARTMENT OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; STEROID; ANTIINFECTIVE AGENT; CANNABIDIOL; DRONABINOL; GLUCOCORTICOID; NICOTINE;

ADULT; ARTICLE; CAUSE OF DEATH; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DISEASE SEVERITY; FEMALE; FOLLOW UP; GASTROINTESTINAL SYMPTOM; HOSPITAL DISCHARGE; HOSPITAL READMISSION; HUMAN; INTEGRATED HEALTH CARE SYSTEM; INTENSIVE CARE UNIT; INTERVIEW; LUNG FUNCTION TEST; LUNG INJURY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY TRACT DISEASE; THORAX RADIOGRAPHY; UNITED STATES; VALIDATION STUDY; VAPING; ACUTE LUNG INJURY; ADVERSE EVENT; ARTIFICIAL VENTILATION; BRONCHOSCOPY; DIAGNOSTIC IMAGING; ELECTRONIC CIGARETTE; EPIDEMIC; LENGTH OF STAY; NONINVASIVE VENTILATION; OXYGEN THERAPY; UTAH; X-RAY COMPUTED TOMOGRAPHY; YOUNG ADULT;

ACUTE LUNG INJURY; ADULT; ANTI-BACTERIAL AGENTS; BRONCHOSCOPY; CANNABIDIOL; COHORT STUDIES; DISEASE OUTBREAKS; DRONABINOL; ELECTRONIC NICOTINE DELIVERY SYSTEMS; FEMALE; GLUCOCORTICOIDS; HUMANS; LENGTH OF STAY; MALE; NICOTINE; NONINVASIVE VENTILATION; OXYGEN INHALATION THERAPY; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; TOMOGRAPHY, X-RAY COMPUTED; UTAH; VAPING; YOUNG ADULT;

EID: 85076083959     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(19)32679-0     Document Type: Article

References (24)

1. US Centers for Disease Control and Prevention. Outbreak of lung injury associated with e-cigarette use, or vaping. 2019, US Centers for Disease Control and Prevention, Atlanta, GA https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html. (Accessed 1 November 2019)
2. Layden, JE, Ghinai, I, Pray, I, et al. Pulmonary illness related to e-cigarette use in Illinois and Wisconsin—preliminary report. N Engl J Med, 2019 published online Sept 6. DOI:10.1056/NEJMoa1911614.
3. Christiani, DC, Vaping-induced lung injury. N Engl J Med, 2019 published online Sept 6. DOI:10.1056/NEJMe1912032.
4. McCauley, L, Markin, C, Hosmer, D, An unexpected consequence of electronic cigarette use. Chest 141 (2012), 1110–1113.
5. Maddock, SD, Cirulis, MM, Callahan, SJ, et al. Pulmonary lipid-laden macrophages and vaping. N Engl J Med 381 (2019), 1488–1489.
6. Henry, TS, Kanne, JP, Kligerman, SJ, Imaging of vaping-associated lung disease. N Engl J Med 381 (2019), 1486–1487.
7. Butt, YM, Smith, ML, Tazelaar, HD, et al. Pathology of vaping-associated lung injury. N Engl J Med, 2019 published online Oct 2. DOI:10.1056/NEJMc1913069.
8. US Centres for Disease Control and Prevention. About electronic cigarettes (e-cigarettes). 2018, US Centres for Disease Control and Prevention, Atlanta, GA https://www.cdc.gov/tobacco/basic_information/e-cigarettes/about-e-cigarettes.html. (Accessed 24 October 2019)
9. Perrine, CG, Pickens, CM, Boehmer, TK, et al. Characteristics of a multistate outbreak of lung injury associated with e-cigarette use, or vaping—United States, 2019. MMWR Morb Mortal Wkly Rep 68 (2019), 860–864.
10. United States Census Bureau. Quickfacts: Utah. 2018, US Department of Commerce https://www.census.gov/quickfacts/fact/table/UT/PST045218. (Accessed 24 October 2019)
11. US Centers for Disease Control and Prevention. National Center for Chronic Disease Prevention and Health Promotion, Division of Population Health. https://www.cdc.gov/brfss/brfssprevalence/, 2015. (Accessed 24 October 2019)
12. Triantafyllou, GA, Tiberio, PJ, Zou, RH, et al. Vaping-associated acute lung injury: a case series. Am J Respir Crit Care Med, 2019 published online Oct 1. DOI:10.1164/rccm.201909-1809LE.
13. Lipsitch, M, Donnelly, CA, Fraser, C, et al. Potential biases in estimating absolute and relative case-fatality risks during outbreaks. PLoS Negl Trop Dis, 9, 2015, e0003846.
14. Fusaro, MV, Becker, C, Scurlock, C, Evaluating tele-ICU implementation based on observed and predicted ICU mortality: a systematic review and meta-analysis. Crit Care Med 47 (2019), 501–507.
15. Intermountain Healthcare. About Intermountain: fast facts. 2019, Intermountain Healthcare, Salt Lake City, UT https://intermountainhealthcare.org/about/who-we-are/fast-facts/. (Accessed 24 October 2019)
16. Utah Office of Administrative Rules. Utah Administrative Code: Rule R386–702. Communicable disease rule. 2019, Office of Administrative Rules, Salt Lake City, UT https://rules.utah.gov/publicat/code/r386/r386-702.htm. (Accessed 24 October 2019)
17. Utah Department of Health. Vaping-related lung injury, Utah, 2019: investigation to date updated September 30, 2019. 2019, Utah Department of Health, Salt Lake City, UT https://health.utah.gov/wp-content/uploads/Vaping-Report-for-Public-9-30-Final.pdf. (Accessed 24 October 2019)
18. Lewis, N, McCaffrey, K, Sage, K, et al. E-cigarette use, or vaping, practices and characteristics among persons with associated lung injury—Utah, April–October 2019. MMWR Morb Mortal Wkly Rep 68 (2019), 953–956.
19. US Centers for Disease Control and Prevention. Primary case definitions: 2019 lung injury surveillance primary case definition (CDC) – September 18, 2019. 2019, US Centers for Disease Control and Prevention, Atlanta, GA https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease/health-departments/index.html#primary-case-def. (Accessed 24 October 2019)
20. Jones, CB, Hill, ML, Pardini, DA, Meier, MH, Prevalence and correlates of vaping cannabis in a sample of young adults. Psychol Addict Behav 30 (2016), 915–921.
21. Christakis, NA, Fowler, JH, The spread of obesity in a large social network over 32 years. N Engl J Med 357 (2007), 370–379.
22. Moore, K, Real-time syndrome surveillance in Ontario, Canada: the potential use of emergency departments and telehealth. Eur J Emerg Med 11 (2004), 3–11.
23. Dran, J, A unique institutional response to the Zika virus epidemic. Obstet Gynecol 131 (2018), 666–670.
24. Wong, YY, Chu, WC, Emphysematous gastritis associated with gastric infarction in a patient with adult polycystic renal disease: CT diagnosis. AJR Am J Roentgenol, 178, 2002, 1291.