Peptide libraries bound to continuous cellulose membranes: Tools to study molecular recognition

Combinatorial Libraries: Synthesis, Screening and Application Potential

Volumn , Issue , 2013, Pages 53-68

  Schneider Mergener, Jens ^a   Kramer, Achim ^a   Reineke, Ulrich ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85067224724     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1515/9783110808902.53     Document Type: Chapter

References (27)

1. Appel, J.R., Pinilla, C, Niman, H., and Houghten, R. A. (1990). Elucidation of discontinuous linear determinants in peptides. J. Immunol. 144, 975-983.
2. Bray, A.M., Maeji, N.J., and Geysen, H.M. (1990). The simultaneous multiple production of solution phase peptides; assessment of the Geysen method of simultaneous peptide synthesis. Tetrahedron Lett. 31, 5811-5814.
3. Bray, A.M., Maeji, N.J., Jhingran, A.G., and Valerio, R.M. (1991). Gas phase cleavage of peptides from a solid support with ammonia vapour. Application in simultaneous multiple peptide synthesis. Tetrahedron Lett. 32,6163-6166.
4. Frank, R. (1992). Spot synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support. Tetrahedron 48,9217-9232.
5. Gallop, M.A., Barret, R.W., Dower, W.J., Fodor, S.P.A., and Gordon, E.M. (1994). Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries. J. Med. Chem. 37,1233-1251.
6. Geysen, H.M., Meloen, R.H., and Barteling, S.J. (1984). Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino aicd. Proc. Natl. Acad. Sci. 81, 3998-4002.
7. Geysen, H.M., Rodda, S.J., and Mason, T.J. (1986). A priori delineation of a peptide which mimics a discontinuous antigenic determinant. Mol. Immunol. 23, 709-715.
8. Geysen, H.M., Rodda, S.J., Mason, T.J., Tribbeck, G., and Schoofs, P.G. (1987). Strategies for epitope analysis using peptide synthesis. J. Immunol. Meth. 102,259-274.
9. Heinrich, P.C., Graeve, L., Rose-John, S., Schneider-Mergener, J., Dittrich, E., Erren, A., Herhartz, C., Hemmann, U., Líitticken, C., Wegenka, U.M., Weiergräber, O. and Friedemann, H. (1995). Membrane-bound and soluble interleukin-6 receptor: Studies on structure, regulation of expression and signal transduction. Ann. New York Acad. Sci. in press.
10. Höhne, W.E., Küttner, G., Kießig, S., Hausdorf, G., Grunow, R., Winkler, K., Wessner, H., Gießmann, E., Stigler, R., Schneider-Mergener, J., V. Baehr, R. and Schomburg, D. (1993). Structural base of the interaction of a monoclonal antibody against p24 of HIV-1 with its peptide epitope. Mol. Immunol. 30,1213-1221.
11. Hoeprich Jr., P.D., Langton, B.C., Zhang, J.-W., and Tarn, J.P. (1989). Identification of immunodominant regions of transforming growth factor a. J. Biol. Chem. 264, 19086-19091.
12. Hoffmann, S., and Frank, R. (1993). New types of reversible peptide-resin linkages for the direct release of peptides and peptide amides into aqueous buffers. Poster 78,13th Am. Peptide Symp., Alberta, Canada.
13. Houghten, R. A. (1985). General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of indvidual amino acids. Proc. Natl Acad. Sci. 82, 5131-5135.
14. Houghten, R.A., Pinilla, C., Blondelle, S.E., Appel, J.R., Dooley, C.T., and Cuervo, J.H. (1991). Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature 354, 84-86.
15. Houghten, R. A. (1993). Peptide libraries: Criteria and trends. Trends Gen. 9,235-239.
16. Jung, G. and Beck-Sickinger, A.G. (1992). Multiple peptide synthesis: Methods and their applications. Angew. Chem. Int. Ed. Engl. 31, 367-383.
17. Kramer, A., Volkmer-Engert, R., Malin, R., Reineke, U. and Schneider-Mergener, J. (1993). Simultaneous synthesis of peptide libraries on single resin and continuous membrane supports: Identification of protein, metal and DNA binding peptide mixtures. Peptide Res. 6, 314-319.
18. Kramer, A., Schuster, A., Reineke, U., Malin, R., Volkmer-Engert, R., Landgraf, C. and Schneider-Mergener, J. (1994). Combinatorial cellulose-bound peptide libraries: Screening tool for the identification of peptides that bind ligands with predefined specificity. METHODS (Comp. Meth. Enzymol.) 6,388-395.
19. Kramer, A., Vakalopoulou, E., Schleuning, W.-D. and Schneider-Mergener, J. (1995). A genearal route to fingerprint analyses of peptide-antibody interactions using a clustered amino acid peptide library: Comparison with a phage display library. Mol. Immunol. 32,459-465.
20. Kramer, A. and Schneider-Mergener, J. (1995). Highly complex combinatorial cellulosebound peptide libraries for the detection of antibody epitopes. In: Peptides 1994 (ESCOM, Leiden), 475-476.
21. Malin, R., Reineke, U., Höhne, W., Semmler, W., Steinbrecher, R. and Schneider-Mergener, J. (1995). Identification of technetium-99m and nickel binding peptides using combinatorial cellulose-bound peptide libraries. In: Peptides 1994, (ESCOM, Leiden), 477-478.
22. Pinilla, C., Appel, J.R., Blanc, P., Houghten, R. A. (1992). Rapid identification of high affinity peptide ligands using positionally scanning synthetic peptide combinatorial libraries. BioTechniques 13, 901-905.
23. Pinilla, C., Appel, J.R., and Houghten, R.A. (1994). Investigation of antigen-antibody interactions using a soluble, non support-bound synthetic decapeptide library composed of four trillion (4 χ IO12) sequences. Biochem. J. 301,847-853.
24. Porstmann, T., Döpel, H., Grunow, R., Henklein, P., and V.Baehr, R. (1990). Detection of immunodominant highly conserved regions within the transmambrane protein of the human immunodeficiency virus 1 by site-directed ELISAs with synthetic peptides and their application for screening purposes. Z. Klin. Chem. 45,341-346.
25. Stigler, R., Rüker, F., Katinger, D, Elliot, G., Höhne, W., Henklein, P., Ho, J. X., Kramer, A., Nugel, E., Porstmann, T. and Schneider-Mergener, J. (1995). Characterisation of the interaction between a Fab fragment against gp41 of HIV-1 and its peptide epitope using a peptide epitope library and molecular modelling. Protein Eng. 8, 471-480.
26. Volkmer-Engert, R., Ehrhard, B., Höhne, W., Ehrhard, B., Kramer, A., Hellwig, J. and Schneider-Mergener, J. (1994). Preparation, analysis and antibody binding studies of simultaneously synthesized soluble and cellulose-bound HIV-1 p24 peptide epitope libraries. Lett. Peptide Sci. 1, 243-253.
27. Winkler, D., Schuster, A., Hoffmann, B. and Schneider-Mergener, J. (1995). Synthesis of cyclic peptide libraries bound to continuous cellulose membrane supports. In: Peptides 1994 (ESCOM, Leiden), 485-486.