Human coronavirus alone or in co-infection with rhinovirus C is a risk factor for severe respiratory disease and admission to the pediatric intensive care unit: A one-year study in Southeast Brazil

PLoS ONE

Volumn 14, Issue 6, 2019, Pages

  Matsuno, Alessandra K ^a   Gagliardi, Talita B ^a   Paula, Flavia E ^a   Luna, Luciano K S ^a   Jesus, Bruna L S ^a   Stein, Renato T ^b   Aragon, Davi C ^a   Carlotti, Ana P C P ^a   Arruda, Eurico ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ARTICLE; BRAZIL; CHILD; COHORT ANALYSIS; CONGENITAL HEART DISEASE; CONTROLLED STUDY; CORONAVIRIDAE; CORONAVIRIDAE INFECTION; DISEASE SEVERITY; EMERGENCY WARD; FEMALE; HOSPITAL ADMISSION; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOFLUORESCENCE TEST; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MOLECULAR BIOLOGY; NASOPHARYNGEAL ASPIRATION; NEWBORN; NONHUMAN; OBSERVATIONAL STUDY; PEDIATRIC INTENSIVE CARE UNIT; PREMATURITY; PROSPECTIVE STUDY; RESPIRATORY TRACT DISEASE; RESPIRATORY VIRUS; RHINOVIRUS; RHINOVIRUS C; RHINOVIRUS C INFECTION; RHINOVIRUS INFECTION; RISK FACTOR; TERTIARY CARE CENTER; UNIVERSITY HOSPITAL; VIRUS DETECTION; VIRUS TYPING; ENTEROVIRUS; INFANT; PHYSIOLOGY; PRESCHOOL CHILD; RESPIRATORY TRACT INFECTION; VIROLOGY;

BRAZIL; CHILD; CHILD, PRESCHOOL; COINFECTION; ENTEROVIRUS; FEMALE; HOSPITALIZATION; HUMANS; INFANT; INTENSIVE CARE UNITS, PEDIATRIC; MALE; RESPIRATORY TRACT INFECTIONS; RISK FACTORS;

EID: 85066618920     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0217744     Document Type: Article

References (27)

1. Global Healthy Observatory Data Repository: World Acute Respiratory Infections. 2016 [accessed on 05 Dec 2017]. In: World Health Organization [internet]. Available from: http://apps.who.int/gho/data/view.main.CM1002015WORLD-CH9?lang=en.
2. Rakes GP, Arruda E, Ingram JM, Hoover GE, Zambrano JC, Hayden FG et al: Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. Am J Respir Crit Care Med. 1999; 159:785–790 https://doi.org/10.1164/ajrccm.159.3.9801052 PMID: 10051251
3. Sonego M, Pellegrin MC, Becker G, Lazzerini M: Risk factors for mortality from acute lower respiratory infections (ALRI) in children under five years of age in low and middle-income countries: a systematic review and meta-analysis of observational studies. PLoS ONE. 2015; 10:e0116380. https://doi.org/10.1371/journal.pone.0116380 PMID: 25635911
4. Arruda E, Jones MH, Escremim de Paula F,Chong D, Bugarin G, Notario G et al: The burden of single virus and viral coinfections on severe lower respiratory tract infections among preterm infants: a prospective birth cohort study in Brazil. Pediatr Infect Dis J. 2014; 33:997–1003. https://doi.org/10.1097/INF.0000000000000349 PMID: 25361184
5. Walsh EE, Breese-Hall C. Respiratory syncytial virus. In: Bennett JE, Dolin R, Blaser MJ, editors. Principles and Practice of Infectious Diseases. 8th Ed. Philadelphia, MS: Elsevier Saunders; 2015. pp. 1948–1960.
6. Legg JP, Warner JA, Johnston SL, Warner JO: Frequency of detection of picornaviruses and seven other respiratory pathogens in infants. Pediatr Infect Dis J. 2005; 24:611–616. https://doi.org/10.1186/ 1471-2334-11-41 PMID: 15999002
7. Fawkner-Corbett DW, Khoo SK, Duarte CM, Bezerra PG, Bochkov YA, Gern JE et al: Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil. J of Med Virol. 2016; 88:58–63. https://doi.org/10.1002/jmv.24300
8. Lauinger IL, Bible JM, Halligan EP, Bangalore H, Tosas O, Aaron EJ et al: Patient characteristics and severity of human rhinovirus infections in children. J Clin Virol. 2013; 58:216–220. https://doi.org/10.1016/j.jcv.2013.06.042 PMID: 23886500
9. Miyaji Y, Kobayashi M, Sugai K, Tsukagoshi H, Niwa S, Fujitsuka-Nozawa A, et al: Severity of respiratory signs and symptoms and virus profiles in Japanese children with acute respiratory illness. Microbiol Immunol. 2013; 57:811–821. https://doi.org/10.1111/1348-0421.12102 PMID: 24117766
10. Chu HY, Englund JA, Strelitz B, Lacombe K, Jones C, Follmer K et al: Rhinovirus disease in children seeking care in a tertiary pediatric emergency department. J Pediatric Infect Dis Soc. 2016; 5:29–38. https://doi.org/10.1093/jpids/piu099 PMID: 26908489
11. Nathan AM, Qiao YL, Jafar FL, Chan YF, Eg KP, Thauagnanam S, et al: Viruses and hospitalization for childhood lower respiratory tract infection in Malaysia: a prospective study. PediatrRespirolCrit Care Med. 2017; 1:46–51. https://doi.org/10.4103/prcm.prcm_2_17
12. Wishaupt JO, van der Ploeg T, de Groot R, Versteegh FG, Hartwig NG: Single- and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen. BMC Infect Dis. 2017; 17:62. https://doi.org/10.1186/s12879-016-2118-6 PMID: 28077074
13. Costa LF, Queiróz DAO, Silveira HL, Bernardino Neto M, de Paula NT, Oliveira TF et al: Human rhinovirus and disease severity in children. Pediatrics. 2014; 133:e312–e321. https://doi.org/10.1542/peds. 2013-2216 PMID: 24420808
14. Cebey-López M, Herberg J, Pardo-Seco J, Gómez-Carballa A, Martinón- Torres N, Salas A et al: Does viral co-infection influence the severity of acute respiratory infection in children? PLoS One. 2016; 11: e0152481. https://doi.org/10.1371/journal.pone.0152481 PMID: 27096199
15. Scotta MC, Chakr VCBG, de Moura A, Becker RG, de Souza AP, Jones MH et al: Respiratory viral coinfection and disease severity in children: a systematic review and meta-analysis. J Clin Virol. 2016; 80:45–56. https://doi.org/10.1016/j.jcv.2016.04.019 PMID: 27155055
16. Cintra OA, Owa MA, Machado AA, Cervi MC, Figueiredo LT, Rocha GM et al: Occurrence and severity of infections caused by subgroup A and B respiratory syncytial virus in children in Southeast Brazil. J Med Virol. 2001; 65:408–412. PMID: 11536252
17. de Souza Luna LK, Heiser V, Regamey N, Panning M, Drexter JF, Mulangu S et al: Generic detection of coronaviruses and differentiation at the prototype strain level by reverse transcription-PCR and non-fluorescent low-density microarray. J Clin Microbiol. 2007; 45:1049–1052. https://doi.org/10.1128/JCM.02426-06 PMID: 17229859
18. Lee WM, Lemanske RF, Evans M, Vang F, Pappas T, Gangnon R et al: Human rhinovirus species and season of infection determine illness severity. Am J Respir Crit Care Med. 2012; 186:886–891. https://doi.org/10.1164/rccm.201202-0330OC PMID: 22923659
19. Lee WM, Kiesner C, Pappas T, Lee L, Grindle K, Jartti T et al: A diverse group of previously unrecognized human rhinoviruses are common causes of respiratory illnesses in infants. PLoS ONE. 2007; 2: e966. https://doi.org/10.1371/journal.pone.0000966 PMID: 17912345
20. Proenca-Modena JL, Pereira Valera FC, Jacob MG, Buzatto GP, Saturno TH, Lopes L et al: High rates of detection of respiratory viruses in tonsillar tissues from children with chronic adenotonsillar disease. PLoS One. 2012; 7:e42136. https://doi.org/10.1371/journal.pone.0042136 PMID: 22870291
21. Blizzard L, Hosmer DW: Parameter estimation and goodness-of-fit inlog binomial regression. Biom J. 2006; 48:5–22. PMID: 16544809
22. Renwick N, Schweiger B, Kapoor V, Liu Z, Villari J Bullmann R et al: A recently identified rhinovirus genotype is associated with severe respiratory-tract infection in children in Germany. J Infect Dis. 2007; 196:1754–1760. https://doi.org/10.1086/524312 PMID: 18190255
23. Do LAH, Bryant JE, Tran AT, Nguyen BH, Tran TTL, Quynh HT et al: Respiratory syncytial virus and other viral infections among children under two years old in Southern Vietnam 2009–2010: clinical characteristics and disease severity. PLoS One. 2016; 11:e0160606. https://doi.org/10.1371/journal.pone. 0160606 PMID: 27500954
24. Zhang S, Tuo J, Huang X, Zhu X, Zhang DM, Zhou K et al: Epidemiology characteristics of human coronaviruses in patients with respiratory infection symptoms and phylogenetic analysis of HCoV-OC43 during 2010–2015 in Guangzhou. PLoS One.2018; 13:e0191789. https://doi.org/10.1371/journal.pone. 0191789 PMID: 29377913
25. Varghese L, Zachariah P, Vargas C, La Russa P, Demmer RT, Furuya YE et al: Epidemiology and clinical features of human coronaviruses in the pediatric population. J Pediatric Infect Dis Soc. 2017. https://doi.org/10.1093/jpids/pix027
26. De Luca M, Donà D, Montagnani C, Lo Vecchio A, Romanengo M, Tagliabue C et al:.Antibiotic prescriptions and prophylaxis in italian children. Is it time to change? Data from the ARPEC project. PLoS One.2016; 11:e0154662. https://doi.org/10.1371/journal.pone.0154662 PMID: 27182926
27. Kelesidis T, Braykov N, Uslan DZ, Morgan DJ, Gandra S, Johannsson B, et al: Indications and types of antibiotic agents used in 6 acute care hospitals, 2009–2010: A pragmatic retrospective observational study. Infect Control Hosp Epidemiol. 2016; 37:70–79. https://doi.org/10.1017/ice.2015.226 PMID: 26456803