Association of Racial Disparities with Access to Kidney Transplant after the Implementation of the New Kidney Allocation System

JAMA Surgery

Volumn 154, Issue 7, 2019, Pages 618-625

  Kulkarni, Sanjay ^a   Ladin, Keren ^b   Haakinson, Danielle ^a   Greene, Erich ^c   Li, Luhang ^c   Deng, Yanhong ^c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BLACK PERSON; COHORT ANALYSIS; CONTROLLED STUDY; DEATH; DECEASED DONOR; ETHNICITY; FEMALE; FOLLOW UP; HEALTH DISPARITY; HISPANIC; HUMAN; HUMAN TISSUE; KIDNEY GRAFT; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; MINORITY GROUP; PANCREAS ISLET; PLASMA; PROBABILITY; RETROSPECTIVE STUDY; SENSITIZATION; SURGERY; ADOLESCENT; AGED; ANCESTRY GROUP; CHRONIC KIDNEY FAILURE; CLINICAL TRIAL; DONOR; EPIDEMIOLOGY; ETHNOLOGY; HOSPITAL ADMISSION; KIDNEY TRANSPLANTATION; MIDDLE AGED; MORBIDITY; MULTICENTER STUDY; PROCEDURES; TRANSPLANTATION; UNITED STATES; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CONTINENTAL POPULATION GROUPS; FEMALE; FOLLOW-UP STUDIES; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; MORBIDITY; RETROSPECTIVE STUDIES; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS; UNITED STATES; WAITING LISTS; YOUNG ADULT;

EID: 85063997004     PISSN: 21686254     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamasurg.2019.0512     Document Type: Article

References (27)

1. Norman SP, Kommareddi M, Luan FL. Inactivity on the kidney transplant wait-list is associated with inferior pre-and post-transplant outcomes. Clin Transplant. 2013; 27 (4): E435-E441. doi: 10.1111/ctr.12173 23923971
2. Patzer RE, Perryman JP, Schrager JD, The role of race and poverty on steps to kidney transplantation in the Southeastern United States. Am J Transplant. 2012; 12 (2): 358-368. doi: 10.1111/j.1600-6143.2011.03927.x 22233181
3. Ladin K, Rodrigue JR, Hanto DW. Framing disparities along the continuum of care from chronic kidney disease to transplantation: barriers and interventions. Am J Transplant. 2009; 9 (4): 669-674. doi: 10.1111/j.1600-6143.2009.02561.x 19344460
4. Axelrod DA, Dzebisashvili N, Schnitzler MA, The interplay of socioeconomic status, distance to center, and interdonor service area travel on kidney transplant access and outcomes. Clin J Am Soc Nephrol. 2010; 5 (12): 2276-2288. doi: 10.2215/CJN.04940610 20798250
5. Hart A, Salkowski N, Snyder JJ, Israni AK, Kasiske BL. Beyond "median waiting time": development and validation of a competing risk model to predict outcomes on the kidney transplant waiting list. Transplantation. 2016; 100 (7): 1564-1570. doi: 10.1097/TP.0000000000001185 27286174
6. Kulkarni S, Hall I, Formica R, Transition probabilities between changing sensitization levels, waitlist activity status and competing-risk kidney transplant outcomes using multi-state modeling. PLoS One. 2017; 12 (12): e0190277. doi: 10.1371/journal.pone.0190277 29287087
7. Grams ME, Massie AB, Schold JD, Chen BP, Segev DL. Trends in the inactive kidney transplant waitlist and implications for candidate survival. Am J Transplant. 2013; 13 (4): 1012-1018. doi: 10.1111/ajt.12143 23399028
8. Andersen PK, Keiding N. Multi-state models for event history analysis. Stat Methods Med Res. 2002; 11 (2): 91-115. doi: 10.1191/0962280202SM276ra 12040698
9. Cortese G, Andersen PK. Competing risks and time-dependent covariates. Biom J. 2010; 52 (1): 138-158. 20029852
10. Israni AK, Salkowski N, Gustafson S, New national allocation policy for deceased donor kidneys in the United States and possible effect on patient outcomes. J Am Soc Nephrol. 2014; 25 (8): 1842-1848. doi: 10.1681/ASN.2013070784 24833128
11. Friedewald JJ, Samana CJ, Kasiske BL, The kidney allocation system. Surg Clin North Am. 2013; 93 (6): 1395-1406. doi: 10.1016/j.suc.2013.08.007 24206858
12. Massie AB, Luo X, Lonze BE, Early changes in kidney distribution under the new allocation system. J Am Soc Nephrol. 2016; 27 (8): 2495-2501. doi: 10.1681/ASN.2015080934 26677865
13. Melanson TA, Hockenberry JM, Plantinga L, New kidney allocation system associated with increased rates of transplants among black and Hispanic patients. Health Aff (Millwood). 2017; 36 (6): 1078-1085. doi: 10.1377/hlthaff.2016.1625 28583967
14. UNOS KN. Odds for receiving a kidney transplant now equal for black, white and Hispanic candidates. 2017; https://unos.org/odds-equal-of-kidney-transplant-for-minorities/. Accessed April 24, 2018.
15. Daniels N. Justice, health, and healthcare. Am J Bioeth. 2001; 1 (2): 2-16. doi: 10.1162/152651601300168834 11951872
16. Patzer RE, Plantinga LC, Paul S, Variation in dialysis facility referral for kidney transplantation among patients with end-stage renal disease in Georgia. JAMA. 2015; 314 (6): 582-594. doi: 10.1001/jama.2015.8897 26262796
17. Patzer RE, Amaral S, Wasse H, Volkova N, Kleinbaum D, McClellan WM. Neighborhood poverty and racial disparities in kidney transplant waitlisting. J Am Soc Nephrol. 2009; 20 (6): 1333-1340. doi: 10.1681/ASN.2008030335 19339381
18. Beyersmann JA, Allignol A, Schumacher M. Competing Risks and Multistate Models in R. New York, NY: Springer; 2011.
19. Grambsch PM, Therneau TM. Proportional hazards tests and diagnostics based on weighted residuals. Biometrika. 1994; 81 (3): 515-526.
20. Andersen PK, Borgan Ø, Gill RD, Keiding N. Statistical Models Based on Counting Processes. New York, NY: Springer; 1993.
21. Putter H, Fiocco M, Geskus RB. Tutorial in biostatistics: competing risks and multi-state models. Stat Med. 2007; 26 (11): 2389-2430. doi: 10.1002/sim.2712 17031868
22. Stewart DE, Klassen DK. Early experience with the new kidney allocation system: a perspective from UNOS. Clin J Am Soc Nephrol. 2017; 12 (12): 2063-2065. doi: 10.2215/CJN.06380617 29162594
23. Stewart DE, Kucheryavaya AY, Klassen DK, Turgeon NA, Formica RN, Aeder MI. Changes in deceased donor kidney transplantation one year after KAS implementation. Am J Transplant. 2016; 16 (6): 1834-1847. doi: 10.1111/ajt.13770 26932731
24. Sapir-Pichhadze R, Tinckam KJ, Laupacis A, Logan AG, Beyene J, Kim SJ. Immune sensitization and mortality in wait-listed kidney transplant candidates. J Am Soc Nephrol. 2016; 27 (2): 570-578. doi: 10.1681/ASN.2014090894 26054537
25. Ladin K, Hanto DW. Understanding disparities in transplantation: do social networks provide the missing clue? Am J Transplant. 2010; 10 (3): 472-476. doi: 10.1111/j.1600-6143.2009.02963.x 20055801
26. Hippen BE, Maddux FW. Integrating kidney transplantation into value-based care for people with renal failure. Am J Transplant. 2018; 18 (1): 43-52. doi: 10.1111/ajt.14454 28898574
27. US Department of Health and Human Services. National Data. https://optn.transplant.hrsa.gov/data/view-data-reports/national-data/#. Accessed May 10, 2018.