메뉴 건너뛰기




Volumn 31, Issue 3, 2019, Pages 285-292

Prediction of infection risk in rheumatoid arthritis patients treated with biologics: are we any closer to risk stratification?

Author keywords

anti tumour necrosis factor; biologics; infection; rheumatoid arthritis; stratification

Indexed keywords

BIOLOGICAL PRODUCT; DENOSUMAB; DISEASE MODIFYING ANTIRHEUMATIC DRUG; GLUCOCORTICOID; NARCOTIC ANALGESIC AGENT; PHARMACOLOGICAL BIOMARKER; RITUXIMAB; TOCILIZUMAB; TUMOR NECROSIS FACTOR INHIBITOR; ANTIRHEUMATIC AGENT; ETANERCEPT;

EID: 85063962633     PISSN: 10408711     EISSN: 15316963     Source Type: Journal    
DOI: 10.1097/BOR.0000000000000598     Document Type: Review
Times cited : (39)

References (47)
  • 1
    • 84997235799 scopus 로고    scopus 로고
    • Treatment preferences of patients with early rheumatoid arthritis: A discrete-choice experiment
    • Hazlewood GS, Bombardier C, Tomlinson G, et al. Treatment preferences of patients with early rheumatoid arthritis: a discrete-choice experiment. Rheumatology 2016; 55:1959-1968.
    • (2016) Rheumatology , vol.55 , pp. 1959-1968
    • Hazlewood, G.S.1    Bombardier, C.2    Tomlinson, G.3
  • 2
    • 84982728026 scopus 로고    scopus 로고
    • A large two-centre study in to rates of influenza and pneumococcal vaccination and infection burden in rheumatoid arthritis in the UK
    • Subesinghe S, Rutherford AI, Ibrahim F, et al. A large two-centre study in to rates of influenza and pneumococcal vaccination and infection burden in rheumatoid arthritis in the UK. BMC Musculoskelet Disord 2016; 17:322.
    • (2016) BMC Musculoskelet Disord , vol.17 , pp. 322
    • Subesinghe, S.1    Rutherford, A.I.2    Ibrahim, F.3
  • 3
    • 85042078890 scopus 로고    scopus 로고
    • Trends in hospitalizations for serious infections in patients with rheumatoid arthritis in the US between 1993 and 2013
    • Jinno S, Lu N, Jafarzadeh SR, et al. Trends in hospitalizations for serious infections in patients with rheumatoid arthritis in the US between 1993 and 2013. Arthritis Care Res (Hoboken) 2018; 70:652-658.
    • (2018) Arthritis Care Res (Hoboken) , vol.70 , pp. 652-658
    • Jinno, S.1    Lu, N.2    Jafarzadeh, S.R.3
  • 5
    • 40349096096 scopus 로고    scopus 로고
    • The safety of antitumour necrosis factor therapy in rheumatoid arthritis
    • Askling J, Dixon W. The safety of antitumour necrosis factor therapy in rheumatoid arthritis. Curr Opin Rheumatol 2008; 20:138-144.
    • (2008) Curr Opin Rheumatol , vol.20 , pp. 138-144
    • Askling, J.1    Dixon, W.2
  • 6
    • 79951712039 scopus 로고    scopus 로고
    • Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: Updated results from the British Society for Rheumatology Biologics Register with special EMPH
    • Galloway JB, Hyrich KL, Mercer LK, et al. Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: updated results from the British Society for Rheumatology Biologics Register with special EMPH. Rheumatology (Oxford) 2011; 50:124-131.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 124-131
    • Galloway, J.B.1    Hyrich, K.L.2    Mercer, L.K.3
  • 7
    • 84937630522 scopus 로고    scopus 로고
    • Risk of serious infection in biological treatment of patients with rheumatoid arthritis: A systematic review and meta-analysis
    • Singh JA, Cameron C, Noorbaloochi S, et al. Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis. Lancet 2015; 386:258-265.
    • (2015) Lancet , vol.386 , pp. 258-265
    • Singh, J.A.1    Cameron, C.2    Noorbaloochi, S.3
  • 8
    • 85063981737 scopus 로고    scopus 로고
    • Ten-year retrospective review of the incidence of serious infections in patients on biologic disease modifying agents for rheumatoid arthritis in three tertiary hospitals in Western Australia
    • Epub ahead of print
    • Sharma C, Keen H. Ten-year retrospective review of the incidence of serious infections in patients on biologic disease modifying agents for rheumatoid arthritis in three tertiary hospitals in Western Australia. Intern Med J 2018; doi: 10.1111/imj.14109. [Epub ahead of print]
    • (2018) Intern Med J
    • Sharma, C.1    Keen, H.2
  • 9
    • 85047417783 scopus 로고    scopus 로고
    • Opportunistic infections in rheumatoid arthritis patients exposed to biologic therapy: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
    • Rutherford AI, Patarata E, Subesinghe S, et al. Opportunistic infections in rheumatoid arthritis patients exposed to biologic therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Rheumatology 2018; 57:997-1001.
    • (2018) Rheumatology , vol.57 , pp. 997-1001
    • Rutherford, A.I.1    Patarata, E.2    Subesinghe, S.3
  • 10
    • 85042146412 scopus 로고    scopus 로고
    • Severe adverse drug reactions to biological disease-modifying antirheumatic drugs in elderly patients with rheumatoid arthritis in clinical practice
    • Leon L, Gomez A, Vadillo C, et al. Severe adverse drug reactions to biological disease-modifying antirheumatic drugs in elderly patients with rheumatoid arthritis in clinical practice. Clin Exp Rheumatol 2018; 36:29-35.
    • (2018) Clin Exp Rheumatol , vol.36 , pp. 29-35
    • Leon, L.1    Gomez, A.2    Vadillo, C.3
  • 11
    • 84903184734 scopus 로고    scopus 로고
    • Serious infections in patients with rheumatoid arthritis and other immune-mediated connective tissue diseases exposed to anti-TNF or rituximab: Data from the Spanish registry BIOBADASER 2
    • Cobo-Ibánẽz T, Descalzo MÁ, Loza-Santamara E, et al. Serious infections in patients with rheumatoid arthritis and other immune-mediated connective tissue diseases exposed to anti-TNF or rituximab: data from the Spanish registry BIOBADASER 2.0. Rheumatol Int 2014; 34:953-961.
    • (2014) 0. Rheumatol Int , vol.34 , pp. 953-961
    • Cobo-Ibánẽz, T.1    Descalzo, M.Á.2    Loza-Santamaŕa, E.3
  • 12
    • 84899901101 scopus 로고    scopus 로고
    • The safety of biologic therapies in RAassociated interstitial lung disease
    • Jani M, Hirani N, Matteson EL, et al. The safety of biologic therapies in RAassociated interstitial lung disease. Nat Rev Rheumatol 2014; 10:284-294.
    • (2014) Nat Rev Rheumatol , vol.10 , pp. 284-294
    • Jani, M.1    Hirani, N.2    Matteson, E.L.3
  • 13
    • 85047238851 scopus 로고    scopus 로고
    • Serious infection across biologic-treated patients with rheumatoid arthritis: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
    • Rutherford AI, Subesinghe S, Hyrich KL, et al. Serious infection across biologic-treated patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Ann Rheum Dis 2018; 77:905-910.
    • (2018) Ann Rheum Dis , vol.77 , pp. 905-910
    • Rutherford, A.I.1    Subesinghe, S.2    Hyrich, K.L.3
  • 14
    • 77949477575 scopus 로고    scopus 로고
    • Drug-specific risk of tuberculosis in patients with rheumatoid arthritis treated with anti-TNF therapy: Results from the British Society for Rheumatology Biologics Register (BSRBR)
    • Dixon WG, Hyrich KL, Watson KD, et al. Drug-specific risk of tuberculosis in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register (BSRBR). Ann Rheum Dis 2010; 69:522-528.
    • (2010) Ann Rheum Dis , vol.69 , pp. 522-528
    • Dixon, W.G.1    Hyrich, K.L.2    Watson, K.D.3
  • 15
    • 84867404899 scopus 로고    scopus 로고
    • You can't always get what you want, but if you try sometimes (with two tests-TST and IGRA-for tuberculosis) you get what you need
    • Winthrop KL, Weinblatt ME, Daley CL. You can't always get what you want, but if you try sometimes (with two tests-TST and IGRA-for tuberculosis) you get what you need. Ann Rheum Dis 2012; 71:1757-1760.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1757-1760
    • Winthrop, K.L.1    Weinblatt, M.E.2    Daley, C.L.3
  • 16
    • 79953018875 scopus 로고    scopus 로고
    • Adverse effects of biologics: A network meta-analysis and Cochrane overview
    • Singh JA, Wells GA, Christensen R, et al. Adverse effects of biologics: a network meta-analysis and Cochrane overview. Cochrane Database Syst Rev 2011; (2):CD008794.
    • (2011) Cochrane Database Syst Rev , vol.2 , pp. CD008794
    • Singh, J.A.1    Wells, G.A.2    Christensen, R.3
  • 17
    • 85020663615 scopus 로고    scopus 로고
    • Drug safety analyses in a rheumatoid arthritis registry: Application of different approaches regarding timing of exposure and confounder measurement
    • Solomon DH, Shadick NA, Weinblatt ME, et al. Drug safety analyses in a rheumatoid arthritis registry: application of different approaches regarding timing of exposure and confounder measurement. Arthritis Res Ther 2017; 19:130.
    • (2017) Arthritis Res Ther , vol.19 , pp. 130
    • Solomon, D.H.1    Shadick, N.A.2    Weinblatt, M.E.3
  • 18
    • 85052588666 scopus 로고    scopus 로고
    • Serious infection risk after 1 year between patients with rheumatoid arthritis treated with rituximab or with a second TNFi after initial TNFi failure: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
    • Silva-Fernández L, De Cock D, Lunt M, et al. Serious infection risk after 1 year between patients with rheumatoid arthritis treated with rituximab or with a second TNFi after initial TNFi failure: results from The British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Rheumatology 2018; 57:1533-1540.
    • (2018) Rheumatology , vol.57 , pp. 1533-1540
    • Silva-Fernández, L.1    De Cock, D.2    Lunt, M.3
  • 19
    • 84877275257 scopus 로고    scopus 로고
    • Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): A randomised, double-blind, controlled phase 4 trial
    • Gabay C, Emery P, van Vollenhoven R, et al. Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial. Lancet (London, England) 2013; 381:1541-1550.
    • (2013) Lancet (London, England) , vol.381 , pp. 1541-1550
    • Gabay, C.1    Emery, P.2    Van Vollenhoven, R.3
  • 20
    • 85009788843 scopus 로고    scopus 로고
    • Drug-specific risk and characteristics of lupus and vasculitis-like events in patients with rheumatoid arthritis treated with TNFi: Results from BSRBR-RA
    • Jani M, Dixon WG, Kearsley-Fleet L, et al. Drug-specific risk and characteristics of lupus and vasculitis-like events in patients with rheumatoid arthritis treated with TNFi: results from BSRBR-RA. RMD Open 2017; 3:e000314.
    • (2017) RMD Open , vol.3 , pp. e000314
    • Jani, M.1    Dixon, W.G.2    Kearsley-Fleet, L.3
  • 21
    • 49549124746 scopus 로고    scopus 로고
    • Use of nonbiologic diseasemodifying antirheumatic drugs and risk of infection in patients with rheumatoid arthritis
    • Lacaille D, Guh DP, Abrahamowicz M, et al. Use of nonbiologic diseasemodifying antirheumatic drugs and risk of infection in patients with rheumatoid arthritis. Arthritis Rheum 2008; 59:1074-1081.
    • (2008) Arthritis Rheum , vol.59 , pp. 1074-1081
    • Lacaille, D.1    Guh, D.P.2    Abrahamowicz, M.3
  • 22
    • 84862509594 scopus 로고    scopus 로고
    • Immediate and delayed impact of oral glucocorticoid therapy on risk of serious infection in older patients with rheumatoid arthritis: A nested case-control analysis
    • Dixon WG, Abrahamowicz M, Beauchamp ME, et al. Immediate and delayed impact of oral glucocorticoid therapy on risk of serious infection in older patients with rheumatoid arthritis: a nested case-control analysis. Ann Rheum Dis 2012; 71:1128-1133.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1128-1133
    • Dixon, W.G.1    Abrahamowicz, M.2    Beauchamp, M.E.3
  • 23
    • 85020923165 scopus 로고    scopus 로고
    • 2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty
    • Goodman SM, Springer B, Guyatt G, et al. 2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty. Arthritis Care Res 2017; 69:1111-1124.
    • (2017) Arthritis Care Res , vol.69 , pp. 1111-1124
    • Goodman, S.M.1    Springer, B.2    Guyatt, G.3
  • 24
    • 85032796496 scopus 로고    scopus 로고
    • Perioperative timing of infliximab and the risk of serious infection after elective hip and knee arthroplasty
    • George MD, Baker JF, Hsu JY, et al. Perioperative timing of infliximab and the risk of serious infection after elective hip and knee arthroplasty. Arthritis Care Res (Hoboken) 2017; 69:1845-1854.
    • (2017) Arthritis Care Res (Hoboken) , vol.69 , pp. 1845-1854
    • George, M.D.1    Baker, J.F.2    Hsu, J.Y.3
  • 25
    • 85068390178 scopus 로고    scopus 로고
    • Changing trends in opioid use among patients with rheumatoid arthritis in the United States
    • Curtis JR, Xie F, Smith C, et al. Changing trends in opioid use among patients with rheumatoid arthritis in the United States. Arthritis Rheumatol 2017; 25:553-559.
    • (2017) Arthritis Rheumatol , vol.25 , pp. 553-559
    • Curtis, J.R.1    Xie, F.2    Smith, C.3
  • 26
    • 85016436670 scopus 로고    scopus 로고
    • Opioids and the immune system: Friend or foe
    • Plein LM, Rittner HL. Opioids and the immune system: friend or foe. Br J Pharmacol 2018; 175:2717-2725.
    • (2018) Br J Pharmacol , vol.175 , pp. 2717-2725
    • Plein, L.M.1    Rittner, H.L.2
  • 27
    • 84956804355 scopus 로고    scopus 로고
    • Opioid analgesics and the risk of serious infections among patients with rheumatoid arthritis: A self-controlled case series study
    • Wiese AD, Griffin MR, Stein CM, et al. Opioid analgesics and the risk of serious infections among patients with rheumatoid arthritis: a self-controlled case series study. Arthritis Rheum 2016; 68:323-331.
    • (2016) Arthritis Rheum , vol.68 , pp. 323-331
    • Wiese, A.D.1    Griffin, M.R.2    Stein, C.M.3
  • 28
    • 85042159418 scopus 로고    scopus 로고
    • Prescription opioids and infection risk: Research and caution needed
    • Dublin S, Von Korff M. Prescription opioids and infection risk: research and caution needed. Ann Intern Med 2018; 168:444.
    • (2018) Ann Intern Med , vol.168 , pp. 444
    • Dublin, S.1    Von Korff, M.2
  • 29
    • 85042167747 scopus 로고    scopus 로고
    • Opioid analgesic use and risk for invasive pneumococcal diseases
    • Wiese AD, Griffin MR, Schaffner W, et al. Opioid analgesic use and risk for invasive pneumococcal diseases. Ann Intern Med 2018; 168:396.
    • (2018) Ann Intern Med , vol.168 , pp. 396
    • Wiese, A.D.1    Griffin, M.R.2    Schaffner, W.3
  • 30
    • 85053479068 scopus 로고    scopus 로고
    • The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: A cohort study
    • Robinson DE, van Staa TP, Dennison EM, et al. The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: a cohort study. Bone 2018; 117:83-90.
    • (2018) Bone , vol.117 , pp. 83-90
    • Robinson, D.E.1    Van Staa, T.P.2    Dennison, E.M.3
  • 31
    • 2342551979 scopus 로고    scopus 로고
    • Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate
    • Genovese MC, Cohen S, Moreland L, et al. Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate. Arthritis Rheum 2004; 50:1412-1419.
    • (2004) Arthritis Rheum , vol.50 , pp. 1412-1419
    • Genovese, M.C.1    Cohen, S.2    Moreland, L.3
  • 32
    • 69049083492 scopus 로고    scopus 로고
    • Denosumab for prevention of fractures in postmenopausal women with osteoporosis
    • Cummings SR, Martin JS, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 2009; 361:756-765.
    • (2009) N Engl J Med , vol.361 , pp. 756-765
    • Cummings, S.R.1    Martin, J.S.2    McClung, M.R.3
  • 33
    • 85041639033 scopus 로고    scopus 로고
    • Occurrence of serious infection in patients with rheumatoid arthritis treated with biologics and denosumab observed in a clinical setting
    • Lau AN, Wong-Pack M, Rodjanapiches R, et al. Occurrence of serious infection in patients with rheumatoid arthritis treated with biologics and denosumab observed in a clinical setting. J Rheumatol 2018; 45:170-176.
    • (2018) J Rheumatol , vol.45 , pp. 170-176
    • Lau, A.N.1    Wong-Pack, M.2    Rodjanapiches, R.3
  • 34
    • 84929925271 scopus 로고    scopus 로고
    • Risk of hospitalized infection among rheumatoid arthritis patients concurrently treated with a biologic agent and denosumab
    • Curtis JR, Xie F, Yun H, et al. Risk of hospitalized infection among rheumatoid arthritis patients concurrently treated with a biologic agent and denosumab. Arthritis Rheumatol 2015; 67:1456-1464.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 1456-1464
    • Curtis, J.R.1    Xie, F.2    Yun, H.3
  • 35
    • 85015311562 scopus 로고    scopus 로고
    • Clinicians' expectations of the benefits and harms of treatments, screening, and tests
    • Hoffmann TC, Del Mar C. Clinicians' expectations of the benefits and harms of treatments, screening, and tests. JAMA Intern Med 2017; 177:407.
    • (2017) JAMA Intern Med , vol.177 , pp. 407
    • Hoffmann, T.C.1    Del Mar, C.2
  • 36
    • 85057262965 scopus 로고    scopus 로고
    • Biologic prescribing decisions following serious infection: Results from the British Society for Rheumatology Biologics Register-Rheumatoid Arthritis
    • Subesinghe S, Rutherford AI, Byng-Maddick R, et al. Biologic prescribing decisions following serious infection: results from the British Society for Rheumatology Biologics Register-Rheumatoid Arthritis. Rheumatology 2018; 57:2096-2100.
    • (2018) Rheumatology , vol.57 , pp. 2096-2100
    • Subesinghe, S.1    Rutherford, A.I.2    Byng-Maddick, R.3
  • 37
    • 84865624563 scopus 로고    scopus 로고
    • Development and validation of a risk score for serious infection in patients with rheumatoid arthritis
    • Crowson CS, Hoganson DD, Fitz-Gibbon PD, et al. Development and validation of a risk score for serious infection in patients with rheumatoid arthritis. Arthritis Rheum 2012; 64:2847-2855.
    • (2012) Arthritis Rheum , vol.64 , pp. 2847-2855
    • Crowson, C.S.1    Hoganson, D.D.2    Fitz-Gibbon, P.D.3
  • 38
    • 84869160661 scopus 로고    scopus 로고
    • Use of a disease risk score to compare serious infections associated with antitumor necrosis factor therapy among highversus lower-risk rheumatoid arthritis patients
    • Curtis JR, Xie F, Chen L, et al. Use of a disease risk score to compare serious infections associated with antitumor necrosis factor therapy among highversus lower-risk rheumatoid arthritis patients. Arthritis Care Res (Hoboken) 2012; 64:1480-1489.
    • (2012) Arthritis Care Res (Hoboken) , vol.64 , pp. 1480-1489
    • Curtis, J.R.1    Xie, F.2    Chen, L.3
  • 39
    • 80053566154 scopus 로고    scopus 로고
    • Treatment benefit or survival of the fittest: What drives the time-dependent decrease in serious infection rates under TNF inhibition and what does this imply for the individual patient?
    • Strangfeld A, Eveslage M, Schneider M, et al. Treatment benefit or survival of the fittest: what drives the time-dependent decrease in serious infection rates under TNF inhibition and what does this imply for the individual patient? Ann Rheum Dis 2011; 70:1914-1920.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1914-1920
    • Strangfeld, A.1    Eveslage, M.2    Schneider, M.3
  • 40
    • 85038128070 scopus 로고    scopus 로고
    • Use of a baseline risk score to identify the risk of serious infectious events in patients with rheumatoid arthritis during certolizumab pegol treatment
    • Curtis JR,Winthrop K, O'Brien C, et al. Use of a baseline risk score to identify the risk of serious infectious events in patients with rheumatoid arthritis during certolizumab pegol treatment. Arthritis Res Ther 2017; 19:276.
    • (2017) Arthritis Res Ther , vol.19 , pp. 276
    • Curtis, J.R.1    Winthrop, K.2    O'Brien, C.3
  • 41
    • 84905196912 scopus 로고    scopus 로고
    • Evaluation of the RABBIT Risk Score for serious infections
    • Zink A, Manger B, Kaufmann J, et al. Evaluation of the RABBIT Risk Score for serious infections. Ann Rheum Dis 2014; 73:1673-1676.
    • (2014) Ann Rheum Dis , vol.73 , pp. 1673-1676
    • Zink, A.1    Manger, B.2    Kaufmann, J.3
  • 42
    • 85080854769 scopus 로고    scopus 로고
    • RABBIT risk score calculator.. [Accessed 5 December
    • RABBIT risk score calculator. http://www.biologika-register.de/en/home/riskscore/. [Accessed 5 December 2018]
    • (2018)
  • 43
    • 84938118511 scopus 로고    scopus 로고
    • Clinical utility of random anti-TNF drug level testing and measurement of antidrug antibodies on long-term treatment response in rheumatoid arthritis
    • Jani M, Chinoy H, Warren RB, et al. Clinical utility of random anti-TNF drug level testing and measurement of antidrug antibodies on long-term treatment response in rheumatoid arthritis. Arthritis Rheumatol 2015; 67:2011-2019.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 2011-2019
    • Jani, M.1    Chinoy, H.2    Warren, R.B.3
  • 44
    • 85009723388 scopus 로고    scopus 로고
    • High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegoltreated patients with rheumatoid arthritis: Results from the BRAGGSS cohort
    • Jani M, Isaacs JD, Morgan AW, et al. High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegoltreated patients with rheumatoid arthritis: results from the BRAGGSS cohort. Ann Rheum Dis 2017; 76:208-213.
    • (2017) Ann Rheum Dis , vol.76 , pp. 208-213
    • Jani, M.1    Isaacs, J.D.2    Morgan, A.W.3
  • 45
    • 85054606963 scopus 로고    scopus 로고
    • Adherence to etanercept therapy in rheumatoid arthritis patients during 3 years of follow-up
    • Vogelzang EH, Hebing RC, Nurmohamed MT, et al. Adherence to etanercept therapy in rheumatoid arthritis patients during 3 years of follow-up. PLoS One 2018; 13:e0205125.
    • (2018) PLoS One , vol.13 , pp. e0205125
    • Vogelzang, E.H.1    Hebing, R.C.2    Nurmohamed, M.T.3
  • 46
    • 85076064722 scopus 로고    scopus 로고
    • The association of biologic drug-levels with infection risk: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
    • Jani M, Dixon WG, Lunt M, et al. The association of biologic drug-levels with infection risk: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Ann Rheum Dis 2018; 77:A163.
    • (2018) Ann Rheum Dis , vol.77 , pp. A163
    • Jani, M.1    Dixon, W.G.2    Lunt, M.3
  • 47
    • 85044837738 scopus 로고    scopus 로고
    • Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimumab concentrations: An open-label, noninferiority, randomised clinical trial
    • L'ami MJ, Krieckaert CLM, Nurmohamed MT, et al. Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimumab concentrations: An open-label, noninferiority, randomised clinical trial. Ann Rheum Dis 2018; 77:484-487.
    • (2018) Ann Rheum Dis , vol.77 , pp. 484-487
    • L'Ami, M.J.1    Krieckaert, C.L.M.2    Nurmohamed, M.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.