Analytical and clinical evaluation of a point-of-care molecular diagnostic system and its influenza A/B assay for rapid molecular detection of the influenza virus

Journal of Infection and Chemotherapy

Volumn 25, Issue 8, 2019, Pages 578-583

  Akashi, Yusaku ^a   Suzuki, Hiromichi ^a   Ueda, Atsuo ^a   Hirose, Yumi ^a   Hayashi, Daisuke ^a   Imai, Hironori ^a   Ishikawa, Hiroichi ^a  

^a TSUKUBA MEDICAL CENTER HOSPITAL   (Japan)

Author keywords

Cobas Influenza A B; Cobas Liat system; Influenza; Point of care testing

Indexed keywords

ADULT; AGED; ANALYTICAL PARAMETERS; ARTICLE; ASSAY; BODY TEMPERATURE; CLINICAL EVALUATION; COUGHING; FALSE POSITIVE RESULT; FEMALE; FEVER; HUMAN; INFLUENZA A; INFLUENZA A B ASSAY; INFLUENZA B; INFLUENZA VIRUS; MAJOR CLINICAL STUDY; MALE; MOLECULAR DIAGNOSIS; NESTED POLYMERASE CHAIN REACTION; OBSERVATIONAL STUDY; POINT OF CARE TESTING; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; ADOLESCENT; GENETICS; INFLUENZA; INFLUENZA A VIRUS; INFLUENZA B VIRUS; MIDDLE AGED; NASOPHARYNX; POINT OF CARE SYSTEM; POLYMERASE CHAIN REACTION; PROCEDURES; VIROLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; FEMALE; HUMANS; INFLUENZA A VIRUS; INFLUENZA B VIRUS; INFLUENZA, HUMAN; MALE; MIDDLE AGED; MOLECULAR DIAGNOSTIC TECHNIQUES; NASOPHARYNX; POINT-OF-CARE SYSTEMS; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 85063040186     PISSN: 1341321X     EISSN: 14377780     Source Type: Journal    
DOI: 10.1016/j.jiac.2019.02.022     Document Type: Article

References (15)

1. Centers for Disease Control and Prevention, Influenza (Flu): Information for Health Professionals. https://www.cdc.gov/flu/professionals/index.htm. (Accessed 22 January 2019)
2. Oguma, T., Saito, R., Masaki, H., Hoshino, K., Zaraket, H., Suzuki, Y., et al. Molecular characteristics of outbreaks of nosocomial infection with influenza A/H3N2 virus variants. Infect Control Hosp Epidemiol 32 (2011), 267–275.
3. Chartrand, C., Leeflang, M.M.G., Minion, J., Brewer, T., Pai, M., Accuracy of rapid influenza diagnostic tests: a meta-analysis. Ann Intern Med 156 (2012), 500–511.
4. Merckx, J., Wali, R., Schiller, I., Caya, C., Gore, G.C., Chartrand, C., et al. Diagnostic accuracy of novel and traditional rapid tests for influenza infection compared with reverse transcriptase polymerase chain reaction: a systematic review and meta-analysis. Ann Intern Med 167 (2017), 394–409.
5. Mason, J., Point-of-care testing for influenza. CADTH issues in emerging health technologies, 2016, Canadian Agency for Drugs and Technologies in Health, Ottawa (ON), 149.
6. Nolte, F.S., Gauld, L., Barrett, S.B., Direct comparison of Alere i and cobas Liat influenza A and B tests for rapid detection of influenza virus infection. J Clin Microbiol 54 (2016), 2763–2766.
7. ® Influenza A/B assay and the Alere i Influenza A&B NEAR isothermal nucleic acid amplification assay for the detection of influenza using adult nasopharyngeal specimens. J Clin Virol 94 (2017), 86–90.
8. Zhang, W.D., Evans, D.H., Detection and identification of human influenza viruses by the polymerase chain reaction. J Virol Methods 33 (1991), 165–189.
9. Ip, D.K., Lau, L.L., Leung, N.H., Fang, V.J., Chan, K.H., Chu, D.K., et al. Viral shedding and transmission potential of asymptomatic and paucisymptomatic influenza virus infections in the community. Clin Infect Dis 64 (2017), 736–742.
10. Chan, K.H., To, K.K., Chan, J.F., Li, C.P., Chen, H., Yuen, K.Y., Analytical sensitivity of seven point-of-care influenza virus detection tests and two molecular tests for detection of avian origin H7N9 and swine origin H3N2 variant influenza A viruses. J Clin Microbiol 51 (2013), 3160–3161.
11. Tokuno, O., Fujiwara, M., Nakajoh, Y., Yamanouchi, S., Adachi, M., Ikeda, A., et al. Comparison of detection sensitivity in rapid-diagnosis influenza virus kits. Kansenshogaku Zasshi 83 (2009), 525–533 [In Japanese with English abstract].
12. Stellrecht, K.A., The drift in molecular testing for influenza: mutations affecting assay performance. J Clin Microbiol 56 (2018), e01531–e01537.
13. Uyeki, T.M., Bernstein, H.H., Bradley, J.S., Englund, J.A., File, T.M. Jr., Fry AM, et al. Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis 68 (2019), e1–e47.
14. Muthuri, S.G., Venkatesan, S., Myles, P.R., Leonardi-Bee, J., Al Khuwaitir, T.S., Al Mamun, A., et al. Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data. Lancet Respir Med 2 (2014), 395–404.
15. Mitamura, K., Shimizu, H., Yamazaki, M., Ichikawa, M., Nagai, K., Katada, J., et al. Clinical evaluation of highly sensitive silver amplification immunochromatography systems for rapid diagnosis of influenza. J Virol Methods 194 (2013), 123–128.