Combined aerobic exercise and high-intensity respiratory muscle training in patients surgically treated for non-small cell lung cancer: A pilot randomized clinical trial

European Journal of Physical and Rehabilitation Medicine

Volumn 55, Issue 1, 2019, Pages 113-122

  Messaggi Sartor, Monique ^a   Marco, Ester ^a,b   Martínez Téllez, Elisabeth ^c   Rodriguez Fuster, Alberto ^a   Palomares, Carolina ^c   Chiarella, Sandra ^a   Muniesa, Josep M ^a   Orozco Levi, Mauricio ^a,d   Barreiro, Esther ^a,d,e   Güell, Maria R ^c  

^a HOSPITAL DEL MAR   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^d Barcelona Biomedical Research Park   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Breathing exercises; Cardiorespiratory fitness; Lung neoplasms; Rehabilitation

Indexed keywords

IGFBP3 PROTEIN, HUMAN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

AGED; BLOOD; BREATHING EXERCISE; CONTROLLED STUDY; EXERCISE; EXERCISE TOLERANCE; FEMALE; HUMAN; KINESIOTHERAPY; LUNG RESECTION; LUNG TUMOR; MALE; METABOLISM; MIDDLE AGED; MUSCLE STRENGTH; NON SMALL CELL LUNG CANCER; PATHOPHYSIOLOGY; PILOT STUDY; PROSPECTIVE STUDY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE;

AGED; BREATHING EXERCISES; CARCINOMA, NON-SMALL-CELL LUNG; EXERCISE; EXERCISE THERAPY; EXERCISE TOLERANCE; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUSCLE STRENGTH; PILOT PROJECTS; PNEUMONECTOMY; PROSPECTIVE STUDIES; QUALITY OF LIFE; SINGLE-BLIND METHOD;

EID: 85062693796     PISSN: 19739087     EISSN: 19739095     Source Type: Journal    
DOI: 10.23736/S1973-9087.18.05156-0     Document Type: Article

References (33)

1. Rochester CL, Fairburn C, Crouch RH. Pulmonary rehabilitation for respiratory disorders other than chronic obstructive pulmonary disease. Clin Chest Med 2014;35:369–89.
2. Nagamatsu Y, Maeshiro K, Kimura NY, Nishi T, Shima I, Yamana H, et al. Long-term recovery of exercise capacity and pulmonary function after lobectomy. J Thorac Cardiovasc Surg 2007;134:1273–8.
3. Jack S, West MA, Raw D, Marwood S, Ambler G, Cope TM, et al. The effect of neoadjuvant chemotherapy on physical fitness and survival in patients undergoing oesophagogastric cancer surgery. Eur J Surg On-col 2014;40:1313–20.
4. Handy JR Jr, Asaph JW, Skokan L, Reed CE, Koh S, Brooks G, et al. What happens to patients undergoing lung cancer surgery? Outcomes and quality of life before and after surgery. Chest 2002;122:21–30.
5. Ni HJ, Pudasaini B, Yuan XT, Li HF, Shi L, Yuan P. Exercise training for patients pre- and postsurgically treated for non-small cell lung cancer: A Systematic Review and Meta-analysis. Integr Cancer Ther 2017;16:63–73.
6. Cesario A, Ferri L, Galetta D, Pasqua F, Bonassi S, Clini E, et al. Post-operative respiratory rehabilitation after lung resection for nonsmall cell lung cancer. Lung Cancer 2007;57:175–80.
7. Spruit MA, Janssen PP, Willemsen SC, Hochstenbag MM, Wouters EF. Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study. Lung Cancer 2006;52:257–60.
8. Gosselink R, De Vos J, van den Heuvel SP, Segers J, Decramer M, Kwakkel G. Impact of inspiratory muscle training in patients with COPD: what is the evidence? Eur Respir J 2011;37:416–25.
9. Crandall K, Maguire R, Campbell A, Kearney N. Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): a systematic review. Surg Oncol 2014;23:17–30.
10. Sasso JP, Eves ND, Christensen JF, Koelwyn GJ, Scott J, Jones LW. A framework for prescription in exercise-oncology research. J Cachexia Sarcopenia Muscle 2015;6:115–24.
11. Brocki BC, Andreasen JJ, Langer D, Souza DS, Westerdahl E. Postoperative inspiratory muscle training in addition to breathing exercises and early mobilization improves oxygenation in high-risk patients after lung cancer surgery: a randomized controlled trial. Eur J Cardiothorac Surg 2016;49:1483–91.
12. Han JY, Choi BG, Choi JY, Lee SY, Ju SY. The prognostic significance of pretreatment plasma levels of insulin-like growth factor (IGF)-1, IGF-2, and IGF binding protein-3 in patients with advanced non-small cell lung cancer. Lung Cancer 2006;54:227–34.
13. Chen B, Liu S, Xu W, Wang X, Zhao W, Wu J. IGF-I and IGFBP-3 and the risk of lung cancer: a meta-analysis based on nested case-control studies. J Exp Clin Cancer Res 2009;28:89.
14. Elloumi M, El Elj N, Zaouali M, Maso F, Filaire E, Tabka Z, et al. IGFBP-3, a sensitive marker of physical training and overtraining. Br J Sports Med 2005;39:604–10.
15. Turner L, Shamseer L, Altman DG, Weeks L, Peters J, Ko-ber T, et al. Consolidated standards of reporting trials (CONSORT) and the completeness of reporting of randomised controlled trials (RCTs) published in medical journals. Cochrane Database Syst Rev 2012;11:MR000030.
16. Black LF, Hyatt RE. Maximal respiratory pressures: normal values and relationship to age and sex. Am Rev Respir Dis 1969;99:696–702.
17. Morales P, Sanchis J, Cordero PJ, Díez JL. [Maximum static respiratory pressures in adults. The reference values for a Mediterranean Caucasian population]. Arch Bronconeumol 1997;33:213–9.
18. Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993;85:365–76.
19. Win T, Jackson A, Sharples L, Groves AM, Wells FC, Ritchie AJ, et al. Cardiopulmonary exercise tests and lung cancer surgical outcome. Chest 2005;127:1159–65.
20. Brunelli A, Salati M. Preoperative evaluation of lung cancer: predicting the impact of surgery on physiology and quality of life. Curr Opin Pulm Med 2008;14:275–81.
21. Jones LW, Eves ND, Peterson BL, Garst J, Crawford J, West MJ, et al. Safety and feasibility of aerobic training on cardiopulmonary function and quality of life in postsurgical nonsmall cell lung cancer patients: a pilot study. Cancer 2008;113:3430–9.
22. Edvardsen E, Skjønsberg OH, Holme I, Nordsletten L, Borchsenius F, Anderssen SA. High-intensity training following lung cancer surgery: a randomised controlled trial. Thorax 2015;70:244–50.
23. Cavalheri V, Jenkins S, Cecins N, Gain K, Phillips MJ, Sanders LH, et al. Exercise training for people following curative intent treatment for non-small cell lung cancer: a randomized controlled trial. Braz J Phys Ther 2017;21:58–68.
24. Mans CM, Reeve JC, Elkins MR. Postoperative outcomes following preoperative inspiratory muscle training in patients undergoing cardiothoracic or upper abdominal surgery: a systematic review and meta analysis. Clin Rehabil 2015;29:426–38.
25. Hinz A, Singer S, Brähler E. European reference values for the quality of life questionnaire EORTC QLQ-C30: results of a German investigation and a summarizing analysis of six European general population normative studies. Acta Oncol 2014;53:958–65.
26. Cavalheri V, Tahirah F, Nonoyama M, Jenkins S, Hill K. Exercise training for people following lung resection for non-small cell lung cancer - a Cochrane systematic review. Cancer Treat Rev 2014;40:585–94.
27. Arbane G, Tropman D, Jackson D, Garrod R. Evaluation of an early exercise intervention after thoracotomy for non-small cell lung cancer (NSCLC), effects on quality of life, muscle strength and exercise tolerance: randomised controlled trial. Lung Cancer 2011;71:229–34.
28. Wang Z, Wang Z, Liang Z, Liu J, Shi W, Bai P, et al. Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer. Onco-Targets Ther 2013;6:1437–44.
29. Meneses-Echávez JF, Jiménez EG, Río-Valle JS, Correa-Bautista JE, Izquierdo M, Ramírez-Vélez R. The insulin-like growth factor system is modulated by exercise in breast cancer survivors: a systematic review and meta-analysis. BMC Cancer 2016;16:682.
30. Weisz JR, Doss AJ, Hawley KM. Youth psychotherapy outcome research: a review and critique of the evidence base. Annu Rev Psychol 2005;56:337–63.
31. Kenny C, Gilheaney Ó, Walsh D, Regan J. Oropharyngeal dysphagia evaluation tools in adult with solid malignancies outside the head and neck and upper GI tract: a systematic review. Dysphagia 2018;33:303–20. [[Epub ahead of print]]
32. Williams MT, Lewis LK, McKeough Z, Holland AE, Lee A, McNamara R, et al. Reporting of exercise attendance rates for people with chronic obstructive pulmonary disease: a systematic review. Respirology 2014;19:30–7.
33. Marco E, Ramírez-Sarmiento AL, Coloma A, Sartor M, Comin-Co-let J, Vila J, et al. High-intensity vs. sham inspiratory muscle training in patients with chronic heart failure: a prospective randomized trial. Eur J Heart Fail 2013;15:892–901.