A Comparative Analysis of Sepsis Identification Methods in an Electronic Database

Critical Care Medicine

Volumn 46, Issue 4, 2018, Pages 494-499

  Johnson, Alistair E W ^a,b   Aboab, Jerome ^a,c   Raffa, Jesse D ^a   Pollard, Tom J ^a,b   Deliberato, Rodrigo O ^a,d   Celi, Leo A ^a,b   Stone, David J ^a,e  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^d HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

critical care; organ failure; sepsis

Indexed keywords

ADULT; AGED; ALL CAUSE MORTALITY; AREA UNDER THE CURVE; ARTICLE; ARTIFICIAL VENTILATION; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DATA BASE; DEMOGRAPHICS; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE CONTROL; ELECTRONIC HEALTH RECORD; FEMALE; HOSPITAL ADMISSION; HOSPITAL COST; HOSPITAL MORTALITY; HUMAN; ICD-9; IN-HOSPITAL MORTALITY; INCIDENCE; INTENSIVE CARE UNIT; LENGTH OF STAY; MALE; MASSACHUSETTS; MULTIPLE ORGAN FAILURE; OUTCOME ASSESSMENT; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SEPSIS; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TEACHING HOSPITAL; TERTIARY CARE CENTER; AGE; ALGORITHM; CODING; EPIDEMIOLOGY; FACTUAL DATABASE; MIDDLE AGED; MORTALITY; ORGAN DYSFUNCTION SCORE; SEVERITY OF ILLNESS INDEX; SEX FACTOR; SOCIOECONOMICS; STATISTICS AND NUMERICAL DATA; VERY ELDERLY;

AGE FACTORS; AGED; AGED, 80 AND OVER; ALGORITHMS; BOSTON; CLINICAL CODING; DATABASES, FACTUAL; FEMALE; HOSPITAL MORTALITY; HOSPITALS, TEACHING; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; MALE; MIDDLE AGED; ORGAN DYSFUNCTION SCORES; RETROSPECTIVE STUDIES; ROC CURVE; SEPSIS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SOCIOECONOMIC FACTORS; TERTIARY CARE CENTERS;

EID: 85062544125     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000002965     Document Type: Article

References (19)

1. Torio CM, Andrews RM: National Inpatient Hospital Costs: The Most Expensive Conditions by Payer, 2011. Rockville, MD, Agency for Healthcare Research and Quality, 2013
2. Torio CM, Moore BJ: National Inpatient Hospital Costs: The Most Expensive Conditions by Payer, 2013. Rockville, MD, Agency for Healthcare Research and Quality, 2016
3. Singer M, Deutschman CS, Seymour CW, et al: The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016; 315:801–810
4. Seymour CW, Liu VX, Iwashyna TJ, et al: Assessment of clinical criteria for sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016; 315: 762–774
5. Raith EP, Udy AA, Bailey M, et al; Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE): Prognostic accuracy of the SOFA Score, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit. JAMA 2017; 317:290–300
6. Sprung CL, Reinhart K: Definitions for sepsis and septic shock. JAMA 2016; 316:456–457
7. Henry J, Pylypchuk Y, Searcy T, et al: Adoption of Electronic Health Record Systems Among US Non-Federal Acute Care Hospitals: 2008–2015. ONC Data Brief, no. 35. The Office of National Coordinator for Health Information Technology, 2016
8. Angus DC, Linde-Zwirble WT, Lidicker J, et al: Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29:1303–1310
9. Martin GS, Mannino DM, Eaton S, et al: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348:1546–1554
10. Johnson AE, Pollard TJ, Shen L, et al: MIMIC-III, a freely accessible critical care database. Sci Data 2016; 3:160035
11. Vincent JL, Moreno R, Takala J, et al: The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996; 22:707–710
12. Centers for Medicare and Medicaid Services: Implementation of Severe Sepsis and Septic Shock: Management Bundle Measure (NQF# 0500). National Quality Forum, 2012
13. Seymour CW, Coopersmith CM, Deutschman CS, et al: Application of a framework to assess the usefulness of alternative sepsis criteria. Crit Care Med 2016; 44:e122–e130
14. Johnson AEW, Pollard TJ: alistairewj/sepsis3-mimic: Sepsis-3 Study v0.1.0. Available at: http://doi.org/10.5281/zenodo.844931. Accessed August 17, 2017
15. Iwashyna TJ, Odden A, Rohde J, et al: Identifying patients with severe sepsis using administrative claims: Patient-level validation of the Angus implementation of the international consensus conference definition of severe sepsis. Med Care 2014; 52:e39–e43
16. Angus DC, Seymour CW, Coopersmith CM, et al: A framework for the development and interpretation of different sepsis definitions and clinical criteria. Crit Care Med 2016; 44:e113–e121
17. Dong PV, Cremer OL: Limitations of the use of the Glasgow Coma Scale in intensive care patients with non-neurological primary disease: A search for alternatives. Crit Care 2011; 15:P506
18. Aboab J, Louis B, Jonson B, et al: Relation between PaO2/FIO2 ratio and FIO2: A mathematical description. Intensive Care Med 2006; 32:1494–1497
19. Vincent JL, Martin GS, Levy MM: qSOFA does not replace SIRS in the definition of sepsis. Crit Care 2016; 20:210