Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: A novel mechanism for an old drug

Cardiovascular Research

Volumn 115, Issue 3, 2019, Pages 625-636

  Bibli, Sofia Iris ^a,b,c   Papapetropoulos, Andreas ^a   Iliodromitis, Efstathios K ^d   Daiber, Andreas ^c,e   Randriamboavonjy, Voahanginirina ^b,c   Steven, Sebastian ^e   Brouckaert, Peter ^f,g   Chatzianastasiou, Athanasia ^a   Kypreos, Kyriakos E ^h   Hausenloy, Derek J ^i,j,k,l,m,n   Fleming, Ingrid ^b,c   Andreadou, Ioanna ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b GOETHE UNIVERSITY   (Germany)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^d NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^e UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^f GHENT UNIVERSITY   (Belgium)

^g DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^h UNIVERSITY OF PATRAS   (Greece)

ⁱ DUKE NUS MEDICAL SCHOOL   (Singapore)

^j DEPARTMENT OF CARDIOLOGY   (Singapore)

^k NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^l UNIVERSITY COLLEGE LONDON   (United Kingdom)

^m UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

ⁿ ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

more..

Author keywords

Cardioprotection; CypD nitros(yl)ation; eNOS; Nitroglycerine

Indexed keywords

ARGININE; CITRULLINE; CYCLOPHILIN D; DIMER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYCERYL TRINITRATE; NITRIC OXIDE; NITRITE; CYCLOPHILIN; ENZYME INHIBITOR; NITRIC OXIDE DONOR; NOS3 PROTEIN, HUMAN; NOS3 PROTEIN, MOUSE; PPID PROTEIN, HUMAN;

ACUTE HEART INFARCTION; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DIMERIZATION; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; FEMALE; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART PROTECTION; HEMODYNAMIC PARAMETERS; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LOW DRUG DOSE; MALE; MOUSE; NITROSATION; NONHUMAN; PRIORITY JOURNAL; REPERFUSION; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; ANIMAL; APOLIPOPROTEIN E KNOCKOUT MOUSE; C57BL MOUSE; CARDIAC MUSCLE CELL; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; GENETICS; HEART INFARCTION; METABOLISM; MIDDLE AGED; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NECROSIS; PATHOLOGY; SIGNAL TRANSDUCTION;

ADULT; AGED; ANIMALS; CYCLOPHILINS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT, APOE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NECROSIS; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE TYPE III; NITROGLYCERIN; NITROSATION; SIGNAL TRANSDUCTION;

EID: 85061990932     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvy222     Document Type: Article

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