Characterisation of a type II functionally-deficient variant of alpha-1-antitrypsin discovered in the general population

PLoS ONE

Volumn 14, Issue 1, 2019, Pages

  Laffranchi, Mattia ^a   Elliston, Emma L K ^b   Gangemi, Fabrizio ^a   Berardelli, Romina ^a   Lomas, David A ^b   Irving, James A ^b   Fra, Annamaria ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; ENZYME ANTIBODY; LEUKOCYTE ELASTASE; MUTANT PROTEIN;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; DISEASE CLASSIFICATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE IDENTIFICATION; GENE STRUCTURE; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CHEMISTRY; GENETIC VARIATION; GENETICS; METABOLISM; POPULATION GENETICS; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE;

ALPHA 1-ANTITRYPSIN; AMINO ACID SEQUENCE; GENETIC VARIATION; GENETICS, POPULATION; HUMANS; MODELS, BIOLOGICAL; MOLECULAR DYNAMICS SIMULATION; MUTANT PROTEINS; PROTEIN DOMAINS; PROTEIN STRUCTURE, SECONDARY;

EID: 85059836372     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0206955     Document Type: Article

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