메뉴 건너뛰기




Volumn 7, Issue 1, 2019, Pages 1-12

Initiation, Continuation, Switching, and Withdrawal of Heart Failure Medical Therapies During Hospitalization

Author keywords

heart failure; medical decision making; medication adherence; medication discontinuation

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; CARVEDILOL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; EPLERENONE; METOPROLOL; METOPROLOL SUCCINATE; MINERALOCORTICOID ANTAGONIST; SACUBITRIL PLUS VALSARTAN; SPIRONOLACTONE; AMINOBUTYRIC ACID DERIVATIVE; SACUBITRIL-VALSARTAN; TETRAZOLE DERIVATIVE;

EID: 85059496909     PISSN: 22131779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchf.2018.06.011     Document Type: Review
Times cited : (124)

References (40)
  • 1
    • 84885457377 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines
    • Yancy, C.W., Jessup, M., Bozkurt, B., et al. 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. J Am Coll Cardiol 62 (2013), 1495–1539.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 1495-1539
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3
  • 2
    • 79957930328 scopus 로고    scopus 로고
    • Patterns and predictors of evidence-based medication continuation among hospitalized heart failure patients (from Get with the Guidelines-Heart Failure)
    • Krantz, M.J., Ambardekar, A.V., Kaltenbach, L., et al. Patterns and predictors of evidence-based medication continuation among hospitalized heart failure patients (from Get with the Guidelines-Heart Failure). Am J Cardiol 107 (2011), 1818–1823.
    • (2011) Am J Cardiol , vol.107 , pp. 1818-1823
    • Krantz, M.J.1    Ambardekar, A.V.2    Kaltenbach, L.3
  • 3
    • 2342424462 scopus 로고    scopus 로고
    • Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure: results of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy in Heart Failure (IMPACT-HF) trial
    • Gattis, W.A., O'Connor, C.M., Gallup, D.S., et al. Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure: results of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy in Heart Failure (IMPACT-HF) trial. J Am Coll Cardiol 43 (2004), 1534–1541.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1534-1541
    • Gattis, W.A.1    O'Connor, C.M.2    Gallup, D.S.3
  • 4
    • 43049173389 scopus 로고    scopus 로고
    • Inpatient initiation of β-blockade plus nurse management in vulnerable heart failure patients: a randomized study
    • Krantz, M.J., Havranek, E.P., Haynes, D.K., Smith, I., Bucher-Bartelson, B., Long, C.S., Inpatient initiation of β-blockade plus nurse management in vulnerable heart failure patients: a randomized study. J Card Fail 14 (2008), 303–309.
    • (2008) J Card Fail , vol.14 , pp. 303-309
    • Krantz, M.J.1    Havranek, E.P.2    Haynes, D.K.3    Smith, I.4    Bucher-Bartelson, B.5    Long, C.S.6
  • 5
    • 58149097941 scopus 로고    scopus 로고
    • Clinical effectiveness of beta-blockers in heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) Registry
    • Hernandez, A.F., Hammill, B.G., O'Connor, C.M., Schulman, K.A., Curtis, L.H., Fonarow, G.C., Clinical effectiveness of beta-blockers in heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) Registry. J Am Coll Cardiol 53 (2009), 184–192.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 184-192
    • Hernandez, A.F.1    Hammill, B.G.2    O'Connor, C.M.3    Schulman, K.A.4    Curtis, L.H.5    Fonarow, G.C.6
  • 6
    • 33845330923 scopus 로고    scopus 로고
    • Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: an analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)
    • Fonarow, G.C., Abraham, W.T., Albert, N.M., et al. Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: an analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). Am Heart J 153 (2007), 82.e1–82.e11.
    • (2007) Am Heart J , vol.153 , pp. 82.e1-82.e11
    • Fonarow, G.C.1    Abraham, W.T.2    Albert, N.M.3
  • 7
    • 46449116410 scopus 로고    scopus 로고
    • Influence of beta-blocker continuation or withdrawal on outcomes in patients hospitalized with heart failure: findings from the OPTIMIZE-HF program
    • Fonarow, G.C., Abraham, W.T., Albert, N.M., et al. Influence of beta-blocker continuation or withdrawal on outcomes in patients hospitalized with heart failure: findings from the OPTIMIZE-HF program. J Am Coll Cardiol 52 (2008), 190–199.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 190-199
    • Fonarow, G.C.1    Abraham, W.T.2    Albert, N.M.3
  • 8
    • 0037066022 scopus 로고    scopus 로고
    • Tolerability of beta-blocker initiation and titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)
    • Gottlieb, S.S., Fisher, M.L., Kjekshus, J., et al. Tolerability of beta-blocker initiation and titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). Circulation 105 (2002), 1182–1188.
    • (2002) Circulation , vol.105 , pp. 1182-1188
    • Gottlieb, S.S.1    Fisher, M.L.2    Kjekshus, J.3
  • 9
    • 0037433183 scopus 로고    scopus 로고
    • Effects of initiating carvedilol in patients with severe chronic heart failure: results from the COPERNICUS Study
    • Krum, H., Roecker, E.B., Mohacsi, P., et al. Effects of initiating carvedilol in patients with severe chronic heart failure: results from the COPERNICUS Study. JAMA 289 (2003), 712–718.
    • (2003) JAMA , vol.289 , pp. 712-718
    • Krum, H.1    Roecker, E.B.2    Mohacsi, P.3
  • 10
    • 85016017429 scopus 로고    scopus 로고
    • Initiation, continuation, or withdrawal of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers and outcomes in patients hospitalized with heart failure with reduced ejection fraction
    • pii:e004675
    • Gilstrap, L.G., Fonarow, G.C., Desai, A.S., et al. Initiation, continuation, or withdrawal of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers and outcomes in patients hospitalized with heart failure with reduced ejection fraction. J Am Heart Assoc, 6, 2017 pii:e004675.
    • (2017) J Am Heart Assoc , vol.6
    • Gilstrap, L.G.1    Fonarow, G.C.2    Desai, A.S.3
  • 11
    • 84990058428 scopus 로고    scopus 로고
    • Renin-angiotensin system inhibition and lower 30-day all-cause readmission in Medicare beneficiaries with heart failure
    • Sanam, K., Bhatia, V., Bajaj, N.S., et al. Renin-angiotensin system inhibition and lower 30-day all-cause readmission in Medicare beneficiaries with heart failure. Am J Med 129 (2016), 1067–1073.
    • (2016) Am J Med , vol.129 , pp. 1067-1073
    • Sanam, K.1    Bhatia, V.2    Bajaj, N.S.3
  • 12
    • 85061886503 scopus 로고    scopus 로고
    • Use of ACE inhibitors or angiotensin receptor blockers is associated with a significantly lower risk of 30-day all-cause and heart failure readmissions and all-cause mortality in older Medicare beneficiaries hospitalized for heart failure developing acute kidney injury (abstr)
    • Siddiqui, M., Sanders, P.W., Arora, G., et al. Use of ACE inhibitors or angiotensin receptor blockers is associated with a significantly lower risk of 30-day all-cause and heart failure readmissions and all-cause mortality in older Medicare beneficiaries hospitalized for heart failure developing acute kidney injury (abstr). Circulation, 132, 2015, A19094.
    • (2015) Circulation , vol.132 , pp. A19094
    • Siddiqui, M.1    Sanders, P.W.2    Arora, G.3
  • 13
    • 22844437062 scopus 로고    scopus 로고
    • Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure
    • Pitt, B., White, H., Nicolau, J., et al. Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure. J Am Coll Cardiol 46 (2005), 425–431.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 425-431
    • Pitt, B.1    White, H.2    Nicolau, J.3
  • 16
    • 34247157767 scopus 로고    scopus 로고
    • Spironolactone reduced arrhythmia and maintained magnesium homeostasis in patients with congestive heart failure
    • Gao, X., Peng, L., Adhikari, C.M., Lin, J., Zuo, Z., Spironolactone reduced arrhythmia and maintained magnesium homeostasis in patients with congestive heart failure. J Card Fail 13 (2007), 170–177.
    • (2007) J Card Fail , vol.13 , pp. 170-177
    • Gao, X.1    Peng, L.2    Adhikari, C.M.3    Lin, J.4    Zuo, Z.5
  • 17
    • 85032636181 scopus 로고    scopus 로고
    • Efficacy and safety of spironolactone in acute heart failure: the ATHENA-HF randomized clinical trial
    • Butler, J., Anstrom, K.J., Felker, G.M., et al. Efficacy and safety of spironolactone in acute heart failure: the ATHENA-HF randomized clinical trial. JAMA Cardiol 2 (2017), 950–958.
    • (2017) JAMA Cardiol , vol.2 , pp. 950-958
    • Butler, J.1    Anstrom, K.J.2    Felker, G.M.3
  • 18
    • 84908372824 scopus 로고    scopus 로고
    • Effect of spironolactone on 30-day death and heart failure rehospitalization (from the COACH Study)
    • Maisel, A., Xue, Y., van Veldhuisen, D.J., et al. Effect of spironolactone on 30-day death and heart failure rehospitalization (from the COACH Study). Am J Cardiol 114 (2014), 737–742.
    • (2014) Am J Cardiol , vol.114 , pp. 737-742
    • Maisel, A.1    Xue, Y.2    van Veldhuisen, D.J.3
  • 19
    • 78650191506 scopus 로고    scopus 로고
    • Spironolactone use at discharge was associated with improved survival in hospitalized patients with systolic heart failure
    • Hamaguchi, S., Kinugawa, S., Tsuchihashi-Makaya, M., et al. Spironolactone use at discharge was associated with improved survival in hospitalized patients with systolic heart failure. Am Heart J 160 (2010), 1156–1162.
    • (2010) Am Heart J , vol.160 , pp. 1156-1162
    • Hamaguchi, S.1    Kinugawa, S.2    Tsuchihashi-Makaya, M.3
  • 20
    • 85005965459 scopus 로고    scopus 로고
    • Lack of evidence of lower 30-day all-cause readmission in Medicare beneficiaries with heart failure and reduced ejection fraction discharged on spironolactone
    • Lam, P.H., Dooley, D.J., Inampudi, C., et al. Lack of evidence of lower 30-day all-cause readmission in Medicare beneficiaries with heart failure and reduced ejection fraction discharged on spironolactone. Int J Cardiol 227 (2017), 462–466.
    • (2017) Int J Cardiol , vol.227 , pp. 462-466
    • Lam, P.H.1    Dooley, D.J.2    Inampudi, C.3
  • 21
    • 84869840351 scopus 로고    scopus 로고
    • Associations between aldosterone antagonist therapy and risks of mortality and readmission among patients with heart failure and reduced ejection fraction
    • Hernandez, A.F., Mi, X., Hammill, B.G., et al. Associations between aldosterone antagonist therapy and risks of mortality and readmission among patients with heart failure and reduced ejection fraction. JAMA 308 (2012), 2097–2107.
    • (2012) JAMA , vol.308 , pp. 2097-2107
    • Hernandez, A.F.1    Mi, X.2    Hammill, B.G.3
  • 22
    • 84880077072 scopus 로고    scopus 로고
    • Transitional adherence and persistence in the use of aldosterone antagonist therapy in patients with heart failure
    • Curtis, L.H., Mi, X., Qualls, L.G., et al. Transitional adherence and persistence in the use of aldosterone antagonist therapy in patients with heart failure. Am Heart J 165 (2013), 979–986.e1.
    • (2013) Am Heart J , vol.165 , pp. 979-986.e1
    • Curtis, L.H.1    Mi, X.2    Qualls, L.G.3
  • 23
    • 77955466458 scopus 로고    scopus 로고
    • Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF)
    • Fonarow, G.C., Albert, N.M., Curtis, A.B., et al. Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF). Circulation 122 (2010), 585–596.
    • (2010) Circulation , vol.122 , pp. 585-596
    • Fonarow, G.C.1    Albert, N.M.2    Curtis, A.B.3
  • 24
    • 33744967948 scopus 로고    scopus 로고
    • Beta-blocker use and outcomes among hospitalized heart failure patients
    • Butler, J., Young, J.B., Abraham, W.T., et al. Beta-blocker use and outcomes among hospitalized heart failure patients. J Am Coll Cardiol 47 (2006), 2462–2469.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 2462-2469
    • Butler, J.1    Young, J.B.2    Abraham, W.T.3
  • 25
    • 36049002112 scopus 로고    scopus 로고
    • Prospective evaluation of beta-blocker use at the time of hospital discharge as a heart failure performance measure: results from OPTIMIZE-HF
    • Fonarow, G.C., Abraham, W.T., Albert, N.M., et al. Prospective evaluation of beta-blocker use at the time of hospital discharge as a heart failure performance measure: results from OPTIMIZE-HF. J Card Fail 13 (2007), 722–731.
    • (2007) J Card Fail , vol.13 , pp. 722-731
    • Fonarow, G.C.1    Abraham, W.T.2    Albert, N.M.3
  • 26
    • 85017185039 scopus 로고    scopus 로고
    • Discontinuation/dose reduction of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers during acute decompensated heart failure in African-American patients with reduced left-ventricular ejection fraction
    • Kane, J.A., Kim, J.K., Haidry, S.A., Salciccioli, L., Lazar, J., Discontinuation/dose reduction of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers during acute decompensated heart failure in African-American patients with reduced left-ventricular ejection fraction. Cardiology 137 (2017), 121–125.
    • (2017) Cardiology , vol.137 , pp. 121-125
    • Kane, J.A.1    Kim, J.K.2    Haidry, S.A.3    Salciccioli, L.4    Lazar, J.5
  • 27
    • 84907087561 scopus 로고    scopus 로고
    • Angiotensin-neprilysin inhibition versus enalapril in heart failure
    • McMurray, J.J., Packer, M., Desai, A.S., et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med 371 (2014), 993–1004.
    • (2014) N Engl J Med , vol.371 , pp. 993-1004
    • McMurray, J.J.1    Packer, M.2    Desai, A.S.3
  • 28
    • 84979929924 scopus 로고    scopus 로고
    • Influence of sacubitril/valsartan (LCZ696) on 30-Day readmission after heart failure hospitalization
    • Desai, A.S., Claggett, B.L., Packer, M., et al. Influence of sacubitril/valsartan (LCZ696) on 30-Day readmission after heart failure hospitalization. J Am Coll Cardiol 68 (2016), 241–248.
    • (2016) J Am Coll Cardiol , vol.68 , pp. 241-248
    • Desai, A.S.1    Claggett, B.L.2    Packer, M.3
  • 29
    • 84957452223 scopus 로고    scopus 로고
    • Comparing LCZ696 with enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores: an analysis of mortality and morbidity in PARADIGM-HF
    • Simpson, J., Jhund, P.S., Silva Cardoso, J., et al. Comparing LCZ696 with enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores: an analysis of mortality and morbidity in PARADIGM-HF. J Am Coll Cardiol 66 (2015), 2059–2071.
    • (2015) J Am Coll Cardiol , vol.66 , pp. 2059-2071
    • Simpson, J.1    Jhund, P.S.2    Silva Cardoso, J.3
  • 30
    • 85016561109 scopus 로고    scopus 로고
    • Early adoption of sacubitril/valsartan for patients with heart failure with reduced ejection fraction: insights from Get With the Guidelines–Heart Failure (GWTG-HF)
    • Luo, N., Fonarow, G.C., Lippmann, S.J., et al. Early adoption of sacubitril/valsartan for patients with heart failure with reduced ejection fraction: insights from Get With the Guidelines–Heart Failure (GWTG-HF). J Am Coll Cardiol HF 5 (2017), 305–309.
    • (2017) J Am Coll Cardiol HF , vol.5 , pp. 305-309
    • Luo, N.1    Fonarow, G.C.2    Lippmann, S.J.3
  • 31
    • 85037147731 scopus 로고    scopus 로고
    • Potential mortality reduction with optimal implementation of angiotensin receptor neprilysin inhibitor therapy in heart failure
    • Fonarow, G.C., Hernandez, A.F., Solomon, S.D., Yancy, C.W., Potential mortality reduction with optimal implementation of angiotensin receptor neprilysin inhibitor therapy in heart failure. JAMA Cardiol 1 (2016), 714–717.
    • (2016) JAMA Cardiol , vol.1 , pp. 714-717
    • Fonarow, G.C.1    Hernandez, A.F.2    Solomon, S.D.3    Yancy, C.W.4
  • 32
    • 85042182529 scopus 로고    scopus 로고
    • Rationale and design of the comParIson Of sacubitril/valsartaN versus Enalapril on Effect on nt-pRo-bnp in patients stabilized from an acute Heart Failure episode (PIONEER-HF) trial
    • Velazquez, E.J., Morrow, D.A., DeVore, A.D., et al. Rationale and design of the comParIson Of sacubitril/valsartaN versus Enalapril on Effect on nt-pRo-bnp in patients stabilized from an acute Heart Failure episode (PIONEER-HF) trial. Am Heart J 198 (2018), 145–151.
    • (2018) Am Heart J , vol.198 , pp. 145-151
    • Velazquez, E.J.1    Morrow, D.A.2    DeVore, A.D.3
  • 33
    • 59749099461 scopus 로고    scopus 로고
    • Acute heart failure syndromes
    • Gheorghiade, M., Pang, P.S., Acute heart failure syndromes. J Am Coll Cardiol 53 (2009), 557–573.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 557-573
    • Gheorghiade, M.1    Pang, P.S.2
  • 34
    • 84942910003 scopus 로고    scopus 로고
    • Contemporary drug development in heart failure: call for hemodynamically neutral therapies
    • Vaduganathan, M., Butler, J., Pitt, B., Gheorghiade, M., Contemporary drug development in heart failure: call for hemodynamically neutral therapies. Circ Heart Fail 8 (2015), 826–831.
    • (2015) Circ Heart Fail , vol.8 , pp. 826-831
    • Vaduganathan, M.1    Butler, J.2    Pitt, B.3    Gheorghiade, M.4
  • 35
    • 56349089733 scopus 로고    scopus 로고
    • Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure)
    • Fonarow, G.C., Abraham, W.T., Albert, N.M., et al. Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure). Am J Cardiol 102 (2008), 1524–1529.
    • (2008) Am J Cardiol , vol.102 , pp. 1524-1529
    • Fonarow, G.C.1    Abraham, W.T.2    Albert, N.M.3
  • 36
    • 84856112414 scopus 로고    scopus 로고
    • Determinants and consequences of renal function variations with aldosterone blocker therapy in heart failure patients post myocardial infarction: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS)
    • Rossignol, P., Cleland, J.G., Bhandari, S., et al. Determinants and consequences of renal function variations with aldosterone blocker therapy in heart failure patients post myocardial infarction: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS). Circulation 125 (2012), 271–279.
    • (2012) Circulation , vol.125 , pp. 271-279
    • Rossignol, P.1    Cleland, J.G.2    Bhandari, S.3
  • 37
    • 85039164574 scopus 로고    scopus 로고
    • 2017 ACC Expert consensus decision pathway for optimization of heart failure treatment: answers to 10 pivotal issues about heart failure with reduced ejection fraction: a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways
    • Yancy, C.W., Januzzi, J.L. Jr., Allen, L.A., et al. 2017 ACC Expert consensus decision pathway for optimization of heart failure treatment: answers to 10 pivotal issues about heart failure with reduced ejection fraction: a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. J Am Coll Cardiol 71 (2018), 201–230.
    • (2018) J Am Coll Cardiol , vol.71 , pp. 201-230
    • Yancy, C.W.1    Januzzi, J.L.2    Allen, L.A.3
  • 38
    • 85021434566 scopus 로고    scopus 로고
    • Clinical trials in acute heart failure: beginning of the end or end of the beginning?
    • Ambrosy, A.P., Butler, J., Gheorghiade, M., Clinical trials in acute heart failure: beginning of the end or end of the beginning?. Eur J Heart Fail 19 (2017), 1358–1360.
    • (2017) Eur J Heart Fail , vol.19 , pp. 1358-1360
    • Ambrosy, A.P.1    Butler, J.2    Gheorghiade, M.3
  • 39
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt, B., Remme, W., Zannad, F., et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 348 (2003), 1309–1321.
    • (2003) N Engl J Med , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3
  • 40
    • 84985994088 scopus 로고    scopus 로고
    • Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens
    • Senni, M., McMurray, J.J., Wachter, R., et al. Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens. Eur Heart J Fail 18 (2016), 1193–1202.
    • (2016) Eur Heart J Fail , vol.18 , pp. 1193-1202
    • Senni, M.1    McMurray, J.J.2    Wachter, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.