Detecting gene mutations in Japanese Alzheimer's patients by semiconductor sequencing

Neurobiology of Aging

Volumn 35, Issue 7, 2014, Pages 1780.e1-1780.e5

  Yagi, Ryoichi ^a,b   Miyamoto, Ryosuke ^a,c   Morino, Hiroyuki ^a   Izumi, Yuishin ^c   Kuramochi, Masahito ^a   Kurashige, Takashi ^d   Maruyama, Hirofumi ^a   Mizuno, Noriyoshi ^b   Kurihara, Hidemi ^b   Kawakami, Hideshi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Alzheimer's disease; APOE; Ion sequencing technology; Mutations; PSEN1; PSEN2

Indexed keywords

PROTON;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; AMPLICON; APOE EPSILON 4 GENE; ARTICLE; CLINICAL FEATURE; FAMILY HISTORY; FEMALE; GENE; GENE DUPLICATION; GENE IDENTIFICATION; GENE MUTATION; GENETIC ANALYSIS; GENETIC PROCEDURES; GENETIC VARIABILITY; HETEROZYGOSITY; HUMAN; HUMAN CELL; ION SEQUENCING TECHNOLOGY; JAPANESE; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; ONSET AGE; PRIORITY JOURNAL; PSEN1 GENE; SEMICONDUCTOR; SEQUENCE ANALYSIS; VERY ELDERLY;

ALZHEIMER'S DISEASE; APOE; ION SEQUENCING TECHNOLOGY; MUTATIONS; PSEN1; PSEN2;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC ASSOCIATION STUDIES; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; MUTATION, MISSENSE; PRESENILIN-1; PRESENILIN-2; PROTONS; SEMICONDUCTORS; SEQUENCE ANALYSIS, DNA;

EID: 85058205886     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.01.023     Document Type: Article

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